NTP 10th Report on Carcinogens. IARC Cancer Review: Group 2A IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 , 1987,p. 204.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 15 , 1977,p. 195.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . NCI Carcinogenesis Bioassay (gavage); Clear Evidence: mouse, rat NCITR*    National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-86 ,1978. ; NTP Carcinogenesis Bioassay (inhalation); Clear Evidence: mouse, rat NTPTR*    National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No. NTP-TR-210 ,1982. . EPA Genetic Toxicology Program. Community Right-To-Know List. Reported in EPA TSCA Inventory.

OSHA PEL: TWA 20 ppm; CL 30 ppm; Pk 50 ppm/5M/8H
ACGIH TLV: Animal Carcinogen
DFG MAK: DFG TRK: Animal Carcinogen, Suspected Human Carcinogen
NIOSH REL: (EDB) 0.045 ppm; CL 1 mg/m³/15M
DOT Classification:  6.1; Label: Poison

For occupational chemical analysis use OSHA: #02 or NIOSH: Ethylene Dibromide, 1008.

The IUPAC name of 1,2-Dibromoethane is 1,2-dibromoethane. With the CAS registry number 106-93-4, it is also named as Aadibroom; Celmide. The product's categories are organics and bromine chemicals. It is colorless to light yellow liquid with a sweetish odor. And it is slightly soluble in water, and soluble in most organic solvents and thinners. In addition, this chemical slowly decomposes in the presence of light and heat, so it may turn brown upon exposure to light. It is corrosive to iron and other metals and may decompose upon contact with alkalis. Furthermore, it is incompatible with oxidizing agents. Reacts with sodium, potassium, calcium, powdered aluminum, zinc, magnesium and liquid ammonia.

The other characteristics of 1,2-Dibromoethanecan be summarized as: 
(1)ACD/LogP: 2.08; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.08; (4)ACD/LogD (pH 7.4): 2.08; (5)ACD/BCF (pH 5.5): 22.42; (6)ACD/BCF (pH 7.4): 22.42; (7)ACD/KOC (pH 5.5): 322.43; (8)ACD/KOC (pH 7.4): 322.43; (9)#H bond acceptors: 0; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 1; (12)Index of Refraction: 1.521; (13)Molar Refractivity: 26.77 cm³; (14)Molar Volume: 87.9 cm³; (15)Polarizability: 10.61×10^-24 cm³; (16)Surface Tension: 36.4 dyne/cm; (17)Enthalpy of Vaporization: 34.77 kJ/mol; (18)Vapour Pressure: 12 mmHg at 25°C; (19)Rotatable Bond Count: 1; (20)Exact Mass: 187.865929; (21)MonoIsotopic Mass: 185.867975; (22)Heavy Atom Count: 4.

Preparation of 1,2-Dibromoethane:
It can be obtained by ethene petroleum ether and bromine under Geschwindigkeit der Reaktion at -80 - -100°C.


Uses of 1,2-Dibromoethane: 
It can be used as ethyl reagents and solvents.In agriculture, it is used as a nematicide and synthetic plant growth regulator. And it is also used as intermediate in synthesis of diethyl-bromophenyl acetonitrile, and fire retardant of vinyl bromide in medicine. In addition, it is used in gasoline to eliminate lead in seismic liquid agent, metal surface treatment agent and fire-fighting agent. It reacts with 2,4,5-tribromo-1H-imidazole to get 2,4,5-tribromo-1-vinylimidazole. This reaction needs reagent aq. tetrabutylammonium bromide and aq. NaOH by heating. The reaction time is 3 hours. The yield is 90 %.


Safety informationg of 1,2-Dibromoethane:
When you are using this chemical, please be cautious about it as the following:It is highly flammable, so it is toxic by inhalation, in contact with skin and if swallowed. And it is irritating to eyes, respiratory system and skin. In addition, this chemical may cause cancer and is toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. If you want to contact this product, you must wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 

People can use the following data to convert to the molecule structure. 
(1)SMILES:BrCCBr;
(2)Std. InChI:InChI=1S/C2H4Br2/c3-1-2-4/h1-2H2;
(3)Std. InChIKey:PAAZPARNPHGIKF-UHFFFAOYSA-N.

The following are the toxicity data of 1,2-Dibromoethane:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
chicken	LD50	oral	79mg/kg (79mg/kg)		AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 6, Pg. 158, 1952.
guinea pig	LCLo	inhalation	400ppm/3H (400ppm)		AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 6, Pg. 158, 1952.
guinea pig	LCLo	inhalation	400ppm/3H (400ppm)	LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), ZONAL"	AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 6, Pg. 158, 1952.
guinea pig	LD50	oral	110mg/kg (110mg/kg)		AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 6, Pg. 158, 1952.
man	TDLo	oral	43uL/kg (0.043mL/kg)	LIVER: "JAUNDICE, OTHER OR UNCLASSIFIED" KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"	Human & Experimental Toxicology. Vol. 19, Pg. 152, 2000.
mouse	LD50	intraperitoneal	220mg/kg (220mg/kg)		Journal fuer Praktische Chemie. Vol. 320, Pg. 133, 1978.
mouse	LD50	unreported	146mg/kg (146mg/kg)		"Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 38, 1971.
mouse	LDLo	oral	250mg/kg (250mg/kg)		Toxicology and Applied Pharmacology. Vol. 23, Pg. 288, 1972.
quail	LD50	oral	130mg/kg (130mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	British Poultry Science. Vol. 22, Pg. 355, 1981.
rabbit	LD50	oral	55mg/kg (55mg/kg)		AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 6, Pg. 158, 1952.
rabbit	LD50	skin	300mg/kg (300mg/kg)		AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 6, Pg. 158, 1952.
rabbit	LD50	skin	300mg/kg (300mg/kg)	SKIN AND APPENDAGES (SKIN): CORROSIVE: AFTER TOPICAL EXPOSURE	AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 6, Pg. 158, 1952.
rabbit	LDLo	rectal	2500mg/kg (2500mg/kg)	LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE"	Journal of Pharmacology and Experimental Therapeutics. Vol. 34, Pg. 223, 1928.
rat	LC50	inhalation	14300mg/m3/30 (14300mg/m3)	PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Farmakologiya i Toksikologiya Vol. 8, Pg. 140, 1973.
rat	LD50	oral	108mg/kg (108mg/kg)		Special Publication of the Entomological Society of America. Vol. 78-1, Pg. 17, 1978.
rat	LD50	skin	300mg/kg (300mg/kg)		"Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel," Perkow, W., Berlin, Verlag Paul Parey, 1971-1976Vol. -, Pg. -, 1971/1976.
women	LDLo	oral	90mg/kg (90mg/kg)	GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" GASTROINTESTINAL: NAUSEA OR VOMITING KIDNEY, URETER, AND BLADDER: URINE VOLUME DECREASED	"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 257, 1969.