Amisulpride (71675-85-9),Amisulpride (71675-85-9) Manufacturers & Suppliers,Synthesis,MSDS

Basic information

Name:
Amisulpride
CAS No.:
71675-85-9
Molecular Structure:
Formula:
C₁₇H₂₇N₃O₄S
Molecular Weight:
369.48
Synonyms:
4-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-o-anisamide;Aminosultopride;4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxy-benzamide;Amisulprida [INN-Spanish];Benzamide, 4-amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-methoxy-;Benzamide,4-amino-N-[(1-ethyl-2- pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2- methoxy-;4-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-anisamid;4-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-methoxybenzamide;Amisulpridum [INN-Latin];Solian;DAN 2163;Methyl ammonia mosapride;
EINECS:
275-831-7
Density:
1.2 g/cm³
Melting Point:
124-128 °C
Boiling Point:
558.9 °C at 760 mmHg
Flash Point:
291.8 °C
Solubility:
DMSO: ≥5 mg/mL
Appearance:
Off-white solid
Hazard Symbols:
Xn
Risk Codes:
22
Safety Description:
22-24/25 Details

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Chemistry

Molecular Structure:

Molecular Formula: C₁₇H₂₇N₃O₄S
Molecular Weight: 369.479
IUPAC Name: 4-Amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxybenzamide
Synonyms of Amisulpride (CAS NO.71675-85-9): Amisulpride [INN] ; Sultopride ; 4-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-anisamid ; 4-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-methoxybenzamide ; 4-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-o-anisamide ; Aminosultopride ; Amisulprida ; Amisulprida [INN-Spanish] ; Amisulpridum ; Amisulpridum [INN-Latin] ; DAN 2163 ; EINECS 275-831-7 ; Solian ; Sulpitac ; UNII-8110R61I4U ; Benzamide, 4-amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-methoxy-
CAS NO: 71675-85-9
Classification Code: Drug / Therapeutic Agent
Melting Point: 124-128 °C
Index of Refraction: 1.545
Molar Refractivity: 97.43 cm³
Molar Volume: 307.7 cm³
Surface Tension: 44.9 dyne/cm
Density: 1.2 g/cm³
Flash Point: 291.8 °C
Enthalpy of Vaporization: 84.11 kJ/mol
Boiling Point: 558.9 °C at 760 mmHg
Vapour Pressure: 1.59E-12 mmHg at 25°C

Uses

Amisulpride (CAS NO.71675-85-9) is a neuroleptic agent and an analogue of sulpiride. Amisulpride is used as an antipsychotic. It is a DOPAMINE receptor antagonist.

Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Source
mouse	LD50	intraperitoneal	175mg/kg (175mg/kg)	United States Patent Document. Vol. #4401822,
mouse	LD50	intravenous	56mg/kg (56mg/kg)	United States Patent Document. Vol. #4401822,
mouse	LD50	oral	1024mg/kg (1024mg/kg)	United States Patent Document. Vol. #4401822,
mouse	LD50	subcutaneous	224mg/kg (224mg/kg)	United States Patent Document. Vol. #4401822,

Safety Profile

Hazard Codes of Amisulpride (CAS NO.71675-85-9): Harmful Xn
Risk Statements: 22
R22: Harmful if swallowed.
Safety Statements: 22-24/25
S22: Do not breathe dust.
S24/25: Avoid contact with skin and eyes.
WGK Germany: 3
RTECS: CV2308701