Basic information
- Name:
Glutaraldehyde
- CAS No.:
111-30-8
- Molecular Structure:

- Formula:
- C5H8O2
- Synonyms:
- Sterihyde L (TN);Bactrocera oleaeOlive fruit fly is also indexed at this headingBactron K 31;Glutaric dialdehyde;Ucarcide 250;Glutaclean;Ucarcide;Panavirocide;Sonacide;Cidex-Dialyzer;Glutarex 28;Glutaraldehyd;1,5-Pentanedial;Glutaraldehyde Solution BP;Pentanedial;Glutaradehyde;1,5 -Pentanedial; Glutaral; Glutaric dialdehyde;Glutaricdialdehyde;glutaraldehyde(25%、50%);glutaraldehyded 50%;Glutaraldehyde25%;Glutarol;Aldesan;Sterihyde L;1,5-Pentanedione;Glutaric acid dialdehyde;Relugan GT;Sporicidin;Floperm 665X1;1,3-Diformylpropane;Pentanedial;Glutaric aldehyde;Glutaraldehude;
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Chemistry
The Molecular Structure of Glutaraldehyde (CAS NO.111-30-8):

Empirical Formula: C5H8O2
Molecular Weight: 100.1158
IUPAC Name: pentanedial
Appearance: Light yellow liquid
Nominal Mass: 100 Da
Average Mass: 100.1158 Da
Monoisotopic Mass: 100.052429 Da
Index of Refraction: 1.399
Molar Refractivity: 25.58 cm3
Molar Volume: 105.7 cm3
Surface Tension: 30.7 dyne/cm
Density: 0.947 g/cm3
Flash Point: 66 °C
Enthalpy of Vaporization: 42.52 kJ/mol
Boiling Point: 189 °C at 760 mmHg
Melting point: -5 ºC
Vapour Pressure: 0.583 mmHg at 25°C
Storage temp: 2-8°C
Water Solubility: miscible
InChI
InChI=1/C5H8O2/c6-4-2-1-3-5-7/h4-5H,1-3H2
Smiles
C(CC=O)CC=O
Product Categories: Pharmaceutical Intermediates;INORGANIC & ORGANIC CHEMICALS;Biocide;Alphabetical Listings;Flavors and Fragrances;G-H
Synonyms of Glutaraldehyde (CAS NO.111-30-8): 1,5-Pentanedial.Pentanedial ; Glutardialdehyde ; Glutaric aldehyde ; Glutaric dialdehyde ; Glutaric acid dialdehyde
Uses
Glutaraldehyde (CAS NO.111-30-8) is used to disinfect medical and dental equipment. It is also used for industrial water treatment and as a chemical preservative. Besides, it is also used in biological electron microscopy as a fixative and used in SDS-PAGE to fix proteins and peptides prior to staining.
Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| duck | LD50 | oral | 820mg/kg (820mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: FOOD INTAKE (ANIMAL) | National Technical Information Service. Vol. OTS0526410-1, |
| guinea pig | LD50 | oral | 50mg/kg (50mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: EXCITEMENT | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 52(3), Pg. 77, 1987. |
| mouse | LD50 | intraperitoneal | 13900ug/kg (13.9mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 10, Pg. 232, 1979. | |
| mouse | LD50 | intravenous | 15400ug/kg (15.4mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 19, Pg. 503, 1980. | |
| mouse | LD50 | oral | 100mg/kg (100mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 19, Pg. 503, 1980. | |
| mouse | LD50 | skin | > 5840mg/kg (5840mg/kg) | SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" | Oyo Yakuri. Pharmacometrics. Vol. 12, Pg. 11, 1976. |
| mouse | LD50 | subcutaneous | > 590mg/kg (590mg/kg) | Drugs in Japan Vol. -, Pg. 395, 1995. | |
| rabbit | LD50 | skin | 560uL/kg (0.56mL/kg) | Union Carbide Data Sheet. Vol. 11/4/1971, | |
| rat | LC50 | inhalation | 480mg/m3/4H (480mg/m3) | United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. Vol. 8EHQ-1290-1008, | |
| rat | LD50 | intraperitoneal | 17900ug/kg (17.9mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 10, Pg. 232, 1979. | |
| rat | LD50 | intravenous | 9800ug/kg (9.8mg/kg) | United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. Vol. 8EHQ-1290-1008, | |
| rat | LD50 | oral | 134mg/kg (134mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 19, Pg. 503, 1980. | |
| rat | LD50 | skin | > 2500mg/kg (2500mg/kg) | SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" | Oyo Yakuri. Pharmacometrics. Vol. 12, Pg. 11, 1976. |
| rat | LD50 | subcutaneous | > 750mg/kg (750mg/kg) | Drugs in Japan Vol. -, Pg. 395, 1995. |
Consensus Reports
Reported in EPA TSCA Inventory.
Safety Profile
Poison by ingestion, intravenous, and intraperitoneal routes. Moderately toxic by inhalation, skin contact, and subcutaneous routes. Experimental teratogenic and reproductive effects. A severe eye and human skin irritant. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes. See also ALDEHYDES.
Hazard Codes:
T,
Xn,
N
Risk Statements: 36/37/38-42/43-34-50-23/25-41-20/22
R36/37/38: Irritating to eyes, respiratory system and skin
R42/43: May cause sensitization by inhalation and skin contact
R34: Causes burns
R50: Very toxic to aquatic organisms
R23/25: Toxic by inhalation and if swallowed
R41: Risk of serious damage to the eyes
R20/22: Harmful by inhalation and if swallowed
Safety Statements: 23-26-45-36/37/39-61
S23: Do not breathe vapour
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection
S61: Avoid release to the environment. Refer to special instructions / safety data sheets
RIDADR: UN 2922 8/PG 2
WGK Germany: 3
RTECS: MA2450000
F: 8-10-23
HazardClass: 8
PackingGroup: II
Standards and Recommendations
OSHA PEL: CL 0.2 ppm
ACGIH TLV: CL 0.05 ppm (skin, sensitizer); Not Classifiable as a Human Carcinogen
DFG MAK: 0.1 ppm (0.42 mg/m3)
Analytical Methods
For occupational chemical analysis use OSHA: #ID-64 or NIOSH: Glutaraldehyde 2531.
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