Basic information
- Name:
L-Tyrosine
- CAS No.:
60-18-4
- Molecular Structure:
- Formula:
- C9H11NO3
- Molecular Weight:
- 181.19
- Deleted CAS:
- 55520-40-6|46209-14-7|1991-85-1|140-43-2
- Synonyms:
- (-)-alpha-Amino-p-hydroxyhydrocinnamic acid;Benzenepropanoic acid, alpha-amino-4-hydroxy-, (S)-;beta-(p-Hydroxyphenyl)alanine;4-Hydroxy-L-phenylalanine;Propanoic acid, 2-amino-3-(4-hydroxyphenyl)-(S)-;alpha-Amino-beta-(4-hydroxyphenyl)propionic acid;Benzenepropanoic acid, .alpha.-amino-4-hydroxy-, (S)-;Tyrosine (USP);2-Amino-3-(4-hydroxyphenyl)propanoic acid-(S)-;Tyrosinum [Latin];L-2-Amino-3-p-hydroxyphenylpropanoic acid;Tirosina [Spanish];Tyrosine, L-;alpha-Amino-p-hydroxyhydrocinnamic acid, (-)-;Tyrosine, L- (8CI);2-Amino-3-(p-hydroxyphenyl)propionic acid;L-Tyrosine (JAN);3-(p-Hydroxyphenyl)alanine;2-Amino-3-(4-hydroxyphenyl)propanoic acid, (S)-;(2S)-2-azaniumyl-3-(4-hydroxyphenyl)propanoate;(S)-2-Amino-3-(p-hydroxyphenyl)propionic acid;(S)-3-(p-Hydroxyphenyl)alanine;(S)-alpha-Amino-4-hydroxybenzenepropanoic acid;Tyrosine [USAN:INN];Propanoic acid, 2-amino-3-(4-hydroxyphenyl)-, (S)-;L-Tyrosine (9CI);(2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid;3-(4-Hydroxyphenyl)-L-alanine;H-Tyr-OH;
- EINECS:
- 200-460-4
- Density:
- 1.334 g/cm3
- Melting Point:
- >300 °C (dec.)(lit.)
- Boiling Point:
- 385.163 °C at 760 mmHg
- Flash Point:
- 186.74 °C
- Solubility:
- 0.45 g/L (25 °C) in water
- Appearance:
- White to off-white powder
- Hazard Symbols:
Xi- Risk Codes:
- 36/37/38-40
- Safety Description:
- 26-36-37/39-22 Details
- particular:
- particular
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Chemistry
Structure of L-Tyrosine (CAS NO.60-18-4):
IUPAC Name: (2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid
Empirical Formula: C9H11NO3
Molecular Weight: 181.1885
EINECS: 200-460-4
Index of Refraction: 1.614
Molar Refractivity: 47.37 cm3
Molar Volume: 135.8 cm3
Polarizability: 18.78×10-24cm3
Surface Tension: 65.7 dyne/cm
Density: 1.333 g/cm3
Flash Point: 186.7 °C
Enthalpy of Vaporization: 66.87 kJ/mol
Melting Point: >300 °C (dec.)(lit.)
Boiling Point: 385.2 °C at 760 mmHg
Vapour Pressure: 1.27E-06 mmHg at 25°C
Water Solubility: 0.45 g/L (25 ºC)
Stability: Stable. Incompatible with strong oxidizing agents, strong reducing agents.
Physical Appearance: White to off-white powder
Product Categories: Food and Feed Additive;Tyrosine [Tyr, Y];Amino Acids;Amino Acids and Derivatives;alpha-Amino Acids;Biochemistry;Nutritional Supplements;L-Amino Acids;Amino Acids
Synonyms of L-Tyrosine (CAS NO.60-18-4): (-)-alpha-Amino-p-hydroxyhydrocinnamic acid ; (S)-Tyrosine ; (S)-alpha-Amino-4-hydroxybenzenepropanoic acid ; 2-Amino-3-(4-hydroxyphenyl)propanoic acid, (S)- ; 4-Hydroxy-L-phenylalanine ;
L-2-Amino-3-p-hydroxyphenylpropanoic acid ; L-Phenylalanine, 4-hydroxy- ; L-p-Tyrosine ; Propanoic acid, 2-amino-3-(4-hydroxyphenyl)-, (S)- ; Tirosina ; Tyrosine ; Tyrosinum ; alpha-Amino-4-hydroxybenzenepropanoic acid, (S)- ; alpha-Amino-beta-(4-hydroxyphenyl)propionic acid ; alpha-Amino-p-hydroxyhydrocinnamic acid, (-)- ; beta-(p-Hydroxyphenyl)alanine ; p-Tyrosine .
Uses
L-Tyrosine (CAS NO.60-18-4) appears to be a successful addition to conventional treatment for COCAINE abuse and withdrawal. It may be used in conjunction with other amino acids such as tryptophan. It can be used as biochemical reagents. It is used for the treatment of THYROID hyperTHYROIDism. It can also be used as a nutrition agent for old and children.
Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | > 1450mg/kg (1450mg/kg) | Yakugaku Zasshi. Journal of Pharmacy. Vol. 97, Pg. 1117, 1977. |
Safety Profile
Hazard Codes: 
Xi
Risk Statements: 36/37/38-40
R36/37/38: Irritating to eyes, respiratory system and skin.
R40: Limited evidence of a carcinogenic effect.
Safety Statements: 26-36-37/39-22
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36: Wear suitable protective clothing.
S37/39: Wear suitable gloves and eye/face protection.
S22: Do not breathe dust.
WGK Germany: 3
RTECS: YP2275600
HS Code: 29225000