Welcome to LookChem.com Sign In | Join Free   Post buying lead  Chemical Tools
Post Buying Lead

Basic information

  • Name:

  • Meropenem

  • CAS No.:

  • 96036-03-2

  • Formula:
  • C17H25N3O5S
  • Synonyms:
  • 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylicacid,3-[[(3S,5S)-5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-,(4R,5S,6S)-;1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylicacid,3-[[5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-,[4R-[3(3S*,5S*),4a,5b,6b(R*)]]-;Antibiotic SM 7338;ICI 194660;Mepem;Meronem;Meropen;Merrem;Merrem IV;SM 7338;

Related products

Other Products

Home > Hot Product_List > Meropenem
Supplier Location:
China (Mainland)(58)United States(5)Brazil(1)Hong Kong(1)India(1)Russian Federation(1)
Business Type:
Importer/Exporter(53)Lab/Research institutions(3)Other(1)
Certificates:
ISO(1)Production License(0)

Please post your buying leads,so that our qualified suppliers will soon contact you!
*Required Fields

Chemistry

IUPAC name: (4R,5S,6S)-3-[(3S,5S)-5-(Dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
Molecular Formula: C17H25N3O5S
Molecular Weight: 383.46 g/mol
Index of Refraction: 1.639
Surface Tension: 68.4 dyne/cm
Density: 1.42 g/cm3
Flash Point: 333.2 °C
Enthalpy of Vaporization: 106.42 kJ/mol
Boiling Point: 627.4 °C at 760 mmHg
Vapour Pressure: 2.27E-18 mmHg at 25 °C 
Product Category of Meropenem (CAS NO.96036-03-2): Active Pharmaceutical Ingredients;Antibacterial;Cnbio;pharmaceutical intermediates
Following is the structure of Meropenem (CAS NO.96036-03-2): 
      

Uses

 Meropenem (CAS NO.96036-03-2) is an ultra-broad spectrum injectable antibiotic used to treat a wide variety of infections, including meningitis and pneumonia. It is a beta-lactam and belongs to the subgroup of carbapenem, similar to imipenem and ertapenem .

Toxicity Data With Reference

 

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo intravenous 2gm/kg (2000mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA		 Chemotherapy Vol. 40(Suppl,
mouse LD50 intravenous 2650mg/kg (2650mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
BEHAVIORAL: ATAXIA		 Chemotherapy Vol. 40(Suppl,
mouse LD50 oral > 5gm/kg (5000mg/kg)   Chemotherapy Vol. 40(Suppl,
mouse LD50 subcutaneous > 5gm/kg (5000mg/kg)   Chemotherapy Vol. 40(Suppl,
rat LD50 intravenous 2850mg/kg (2850mg/kg) PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE
BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
LUNGS, THORAX, OR RESPIRATION: DYSPNEA		 Chemotherapy Vol. 40(Suppl,
rat LD50 oral > 5gm/kg (5000mg/kg)   Chemotherapy Vol. 40(Suppl,
rat LD50 subcutaneous > 5gm/kg (5000mg/kg)   Chemotherapy Vol. 40(Suppl,

Safety Profile

Hazard Codes: IrritantXi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-37/39 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S37/39:Wear suitable gloves and eye/face protection.

Specification

 Meropenem , its cas register number is 96036-03-2. It also can be called Meropenemum ; and Merrem .
 Meropenem (CAS NO.96036-03-2) was originally developed by Sumitomo Pharmaceuticals. It is marketed outside Japan by AstraZeneca with the brand names Merrem and Meronem . Other brand names include Mepem (Taiwan) , Meropen (Japan, Korea) and Neopenem (India) . It gained FDA approval in July 1996. It penetrates well into many tissues and body fluids including the cerebrospinal fluid, bile, heart valves, lung, and peritoneal fluid.

©2008 LookChem.com,License:ICP NO.：Zhejiang10014259

[Hangzhou]86-571-85317600,85317603,85317620