Reference

Hydrolysis of nitriles

Hydrolysis of nitriles. Alkaline hydrolysis of some unsaturated alpha-beta-nitriles; derivatives of benzylidene-p-chlorophenylacetonitrile. Zavoianu, Dinu; Moga Gheorghe, Spiridon; Cuza, Olga (Inst. Politeh., Fac. 93986-80-2 and 140-53-4 are cas registry numbers. These chemicals are also mentioned in this article. Technol. Chim., Bucharest, Rom.). Rev. Chim. (Bucharest), 37(6), 461-4 (Romanian) 1986. CODEN: RCBUAU. DOCUMENT TYPE: Journal CA Section: 22 (Physical Organic Chemistry) Rate consts. and activation parameters for the alk. hydrolyses of nitriles [I; R = H, 2-, 3-, or 4-Cl or -NO2, 4-MeO, 3,4-(OCH2O), Me2N] were measured. .

Azolylmethylcycloalkanes and their use

Azolylmethylcycloalkanes and their use. Janssen, Bernd; Meyer, Norbert; Kohlmann, Friedrich Wilhelm; Wesenberg, Walter; Heberle, Wolfgang (BASF A.-G. , Fed. 140-53-4 which is the cas registry number is also used here. Rep. Ger.). Ger. Offen. DE 3307479 A1 13 Sep 1984, 20 pp. (German). (Germany). CODEN: GWXXBX. CLASS: IC: C07D249-08; C07D233-56; A61K031-41; A61K031-415. APPLICATION: DE 83-3307479 3 Mar 1983. DOCUMENT TYPE: Patent CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Section cross-reference(s): 1, 10 The title compds. [I; R, R1 = H, halo; R2, R3 = H, naphthyl, heteroaryl, biphenylyl, (un)substituted alkyl, Ph; Z = CH, N; n = 0-2; m = 1-4] were prepd. Thus, 1-(4-chlorophenyl)cyclobutanecarboxylic acid was reduced with LiAlH4 to give the hydroxymethyl deriv., which was esterified with MeSO2Cl and treated with 1H-1,2,4-triazole to give cyclobutylmethyltriazole II. I are effective fungicides against dermatophytes with min. inhibitory concns. 0.5-16 mg/mL. .