Detail of "2592-95-2"

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CAS Number:
2592-95-2
Name:
1-Hydroxybenzotriazole
Molecular Structure:
Formula:
C₆H₅N₃O
Molecular Weight:
135.14
Synonyms:
1H-Benzotriazole,1-hydroxy-;1-Hydroxybenzotriazole(HOBt);HOBT, anhydrous;Benzotriazol-1-ol;1-Hydroxybenzotriazole anhydrous (HOBt);1-Hydroxybenzotrizole;HOBT (1-Hydroxybenzotrizole);1-Hydroxybenzotriazole (HOBT);1-Hydroxy Benzotrizole;Benzazimidol;HOBt anhydrous;1-Hydroxybenzotriazole anhydrous (HOBT anh.);
EINECS:
219-989-7
Density:
1.51 g/cm³
Melting Point:
156-159 °C
Boiling Point:
344.6 °C at 760 mmHg
Flash Point:
162.2 °C
Appearance:
white to light yellow powder
Hazard Symbols:
F,Xi,T
Risk Codes:
11-5-36/38-36/37/38-36-20/21-61
Safety:
16-33-7/9-26-45-53-15 Details

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CAS No.2592-95-2 1-Hydroxybenzotriazole

1-Hydroxybenzotriazole

Supplier:Shanghai Unifavor Chemical Co., Ltd[ China (Mainland)]

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Reference

Nucleic acid base grafted macromolecules: their synthesis and interactions: Nucleic acid base grafted macromolecules: their synthesis and interactions. Gunn, V. E.; Overberger, C. G. (Macromol. Res. Cent., Univ. Michigan, Ann Arbor, MI 48109, USA). Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.), 25(2), 25-6 (English) 1984. CODEN: ACPPAY. ISSN: 0032-3934. DOCUMENT TYPE: Journal CA Section: 35 (Chemistry of Synthetic High Polymers) Section cross-reference(s): 63 Linear poly(trimethylenimines) (I) having varying mol. wts. were acylated (optionally in the presence of acylation catalysts) with thymine-substituted propionic acids. I were prepd. by carbocationic ring-opening polymn. of 2-phenyl-2-oxazine (II) using a variety of catalysts followed by hydrolysis. A 1:1 mixt. of MeI [74-88-4]/BF3.OEt2 [109-63-7] was the best catalyst system for the ring-opening polymn. of II. The mol. wts. of I were directly proportional to the II-initiator ratio. The use of N-(phenylphosphoryl)-5-norbornene-2,3-dicarboximide [94196-30-2] catalyst was the most efficient means of prepg. racemic I derivs. Optically active I derivs. were obtained by acylating I with the corresponding optically active 2-(thymin-1-yl)propionic acid [62031-78-1] in the presence of 1-hydroxybenzotriazole [2592-95-2] and dicyclohexylcarbodiimide [538-75-0]. The nucleic acid base-substituted I derivs. show potential antiviral and antitumor properties.

Determination of steroid hormone glucuronides: Determination of steroid hormone glucuronides. March, Steven Carl (Abbott Laboratories, USA). Eur. Pat. Appl. EP 114614 A2 1 Aug 1984, 18 pp. DESIGNATED STATES: R: BE, DE, FR, GB, IT. (English). (European Patent Organization). CODEN: EPXXDW. CLASS: IC: G01N033-74; G01N033-54. APPLICATION: EP 84-100249 12 Jan 1984. PRIORITY: US 83-460739 25 Jan 1983. DOCUMENT TYPE: Patent CA Section: 2 (Mammalian Hormones) An enzyme immunoassay for urinary pregnanediol glucuronide (I) is described. Anti-I antibodies raised in a goat are used and the prepn. of the I tracer soln. comprising I covalently attached to alk. phosphatase is described. Thus, I is treated with N-hydroxysuccinimide [6066-82-6], 1-hydroxybenztriazole [2592-95-2], and N,N-dicyclohexylcarbodiimide [538-75-0] in DMF to form the I active ester which is then reacted with alk. phosphatase in DMF in M ratios of , , (I/alk. phosphatase). In the assay procedure a urine sample is mixed with a portion of the I tracer soln. and a std. vol. of I-antibody soln. and incubated at 37° for 10 min. A double-antibody precipitin suspension comprising normal goat serum and porcine antigoat serum is then added and the mixt. is incubated an addnl. 10 min. After centrifugation aliquots of the supernatant are treated with an alk. phosphatase reagent incubated at room temp. for 15 min and the absorbance of the sample is read at a wavelength suitable for p-nitrophenol and compared to a std. curve.

Detail of "2592-95-2"

1-Hydroxybenzotriazole

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CAS No.2592-95-2 1-Hydroxybenzotriazole

CAS No.2592-95-2 1-Hydroxybenzotriazole

CAS No.2592-95-2 1-Hydroxybenzotriazole

CAS No.2592-95-2 1-Hydroxybenzotriazole

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CAS No.2592-95-2 1-Hydroxybenzotriazole

CAS No.2592-95-2 1-Hydroxybenzotriazole

CAS No.2592-95-2 1-Hydroxybenzotriazole

CAS No.2592-95-2 1-Hydroxybenzotriazole

CAS No.2592-95-2 1-Hydroxybenzotriazole

CAS No.2592-95-2 1-Hydroxybenzotriazole

CAS No.2592-95-2 1-Hydroxybenzotriazole

CAS No.2592-95-2 1-Hydroxybenzotriazole

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CAS No.2592-95-2 1-Hydroxybenzotriazole

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CAS No.2592-95-2 1-Hydroxybenzotriazole

CAS No.2592-95-2 1-Hydroxybenzotriazole

CAS No.2592-95-2 1-Hydroxybenzotriazole

CAS No.2592-95-2 1-Hydroxybenzotriazole

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CAS No.2592-95-2 1-Hydroxybenzotriazole

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Reference