Reference

Effect of parasympathetic agents on renin secretion in vitro

Effect of parasympathetic agents on renin secretion in vitro. Fedorov, V. I. (Novosibirsk Med. Inst., Novosibirsk, USSR). Byull. Eksp. Biol. Med., 97(3), 305-7 (Russian) 1984. CODEN: BEBMAE. ISSN: 0365-9615. DOCUMENT TYPE: Journal CA Section: 2 (Mammalian Hormones) Section cross-reference(s): 1 The nicotinic cholinominectis (N-cholinomimetics) nicotine [54-11-5] and cytiton [485-35-8] markedly inhibited renin [9015-94-5] secretion by rat kidney sections after a- and b-adrenergic receptor blockade. Spasmolytin and benzohexonium (N-cholinolytic and ganglion blocker, resp.) dose dependently stimulated (10-20-fold) renin secretion. The muscarinic cholinomimetics (M-cholinomimetic) arecolidine [57680-57-6] and proserine [51-60-5] and quateron [3818-40-4] increased renin secretion 3-5-fold independently of the dose. Pilocarpine and the M-cholinolytics atropine and pratyphylline, decreased renin secretion 2-fold, also independently of the dose. Apparently, the kidney cortex contains N-cholinoreactive systems that have a direct or mediated action on renin secretion and M-cholinoreactive systems that modulate the activity of the former system.

Pharmacological characterization of acetylcholine and L-glutamate receptors of the subpharyngeal ganglion of the mollusk Zachrysia guanensis

Pharmacological characterization of acetylcholine and L-glutamate receptors of the subpharyngeal ganglion of the mollusk Zachrysia guanensis. Martines-Soler, R.; Menenuss, R.; Geratex, A.; Demushkin, V. P.; Plyashkevich, Yu. G. (Brain Inst., Acad. Sci. Cuba, Cuba). Byull. Eksp. Biol. Med., 98(9), 312-15 (Russian) 1984. CODEN: BEBMAE. ISSN: 0365-9615. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) Section cross-reference(s): 12 The presence of acetylcholine and L-glutamate receptors sensitive to the cholinoreceptor-specific ligands cytisine [485-35-8] and tubocurarine [57-94-3] was demonstrated by means of microapplication of acetylcholine and L-glutamate to the central parietal zone of the subpharyngeal ganglion of the mollusk Z. guanensis. N-(p-Azidophenacyl)cytisine [82438-75-3] inhibited the function of the acetylcholine receptor but did not affect the glutamate receptor.