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| CAS No.: | 5704-04-1 |
|---|---|
| Name: | Tricine |
| Article Data: | 4 |
| Molecular Structure: | |
|
|
|
| Formula: | C6H13NO5 |
| Molecular Weight: | 179.173 |
| Synonyms: | N-[2-Hydroxy-1,1-bis(hydroxymethyl)ethyl]glycine;N-[Tris(hydroxymethyl)methyl]glycine;NSC 369995; |
| EINECS: | 227-193-6 |
| Density: | 1.449 g/cm3 |
| Melting Point: | 186-188 °C (dec.) |
| Boiling Point: | 500.9 °C at 760 mmHg |
| Flash Point: | 256.7 °C |
| Solubility: | water: 4 M at 20 °C, clear, colorless |
| Appearance: | White/clear crystalline powder |
| Hazard Symbols: |
 Xi
|
| Risk Codes: | 36/37/38 |
| Safety: | 26-36-36/37/39 |
| PSA: | 110.02000 |
| LogP: | -2.23280 |
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| Conditions | Yield |
|---|---|
| With hydrogenchloride; tin(ll) chloride In water at 100℃; for 0.166667h; pH=5.0; Succinate buffer; | 95% |
- 5704-04-1
N-[tris(hydroxymethyl)methyl]glycine
| Conditions | Yield |
|---|---|
| With hydrogenchloride; tin(ll) chloride In ethanol; water at 100℃; for 0.166667h; pH=5.0; | 95% |
- 5704-04-1
N-[tris(hydroxymethyl)methyl]glycine
| Conditions | Yield |
|---|---|
| With hydrogenchloride; tin(ll) chloride In water at 100℃; for 0.25h; pH=5.0; Succinate buffer; | 95% |
- 5704-04-1
N-[tris(hydroxymethyl)methyl]glycine
- 27668-52-6
octadecyldimethyl[3-(trimethoxysilyl)propyl]ammonium chloride
| Conditions | Yield |
|---|---|
| Stage #1: N-[tris(hydroxymethyl)methyl]glycine; octadecyldimethyl[3-(trimethoxysilyl)propyl]ammonium chloride In N,N-dimethyl-formamide at 145℃; Stage #2: With sodium methylate In N,N-dimethyl-formamide | 89% |
| Conditions | Yield |
|---|---|
| In water Re(CO)3(H2O)3Br (0.371 mmol), tricine (0.0445 mmol), NEt3 (1.12 mmol) inH2O refluxed (0.5 h); solvent removed; washed with acetone; elem. anal.; | 88% |
- 5704-04-1
N-[tris(hydroxymethyl)methyl]glycine
| Conditions | Yield |
|---|---|
| In water at 130℃; for 12h; | 88% |
| Conditions | Yield |
|---|---|
| With KOH In ethanol Co-salt in H2O added slowly to tricine in EtOH with stirring, mercapto-comp. in EtOH added dropwise with stirring, pH ajusted to 8 with 0.1 M KOH, refluxed for 5 h; evapd., cooled, filtered, washed with H2O and EtOH, dried in vac. over P4H10, elem. anal.; | 55% |
| Conditions | Yield |
|---|---|
| With KOH In ethanol Ni-salt in H2O added slowly to tricine in EtOH with stirring, mercapto-comp. in EtOH added dropwise with stirring, pH ajusted to 8 with 0.1 M KOH, refluxed for 5 h; evapd., cooled, filtered, washed with H2O and EtOH, dried in vac. over P4H10, elem. anal.; | 53% |
- 5704-04-1
N-[tris(hydroxymethyl)methyl]glycine
- 134469-07-1
Benzimidazol-2-thiol
| Conditions | Yield |
|---|---|
| With KOH In ethanol Cu-salt in H2O added slowly to tricine in EtOH with stirring, mercapto-comp. in EtOH added dropwise with stirring, pH ajusted to 8 with 0.1 M KOH, refluxed for 5 h; evapd., cooled, filtered, washed with H2O and EtOH, dried in vac. over P4H10, elem. anal.; | 52% |
| Conditions | Yield |
|---|---|
| With KOH In ethanol; water soln. of nitrate salt in water added slowly to soln. of tricine in C2H5OH with stirring, soln. of hydroxyquinoline in C2H5OH added dropwise withstirring, adjusting pH to 8 by aq. KOH, mixt. refluxed for 5 h; mixt. evapd., cooled, ternary complex filtered off, washed (H2O, C2H5OH), dried (vac., P4O10); elem. anal.; | 51% |
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Chemistry
IUPAC Name: 2-[[1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl]amino]acetic acid
Synonyms: N-[1,3-Dihydroxy-2-(hydroxymethyl)-2-propanyl]glycine ; N-[1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl]glycine ; N-[2-Hydroxy-1,1-bis(hydroxymethyl)ethyl]glycine ; Glycine, N-(2-hydroxy-1,1-bis(hydroxymethyl)ethyl)- ; N-(2-hydroxy-1,1-bis[hydroxymethyl]ethyl)glycine ; N-(tri(hydroxymethyl)methyl)glycine ; N-(Trishydroxymethylmethyl)glycine
The Molecular Formula of Tricine (5704-04-1):C6H13NO5
The Molecular Weight of Tricine (5704-04-1):179.1711 g/mol
The Molecular Structure of Tricine (5704-04-1):
Index of Refraction: 1.553
Molar Refractivity: 39.57 cm3
Molar Volume: 123.5 cm3
Surface Tension: 76.8 dyne/cm
Density: 1.449 g/cm3
Flash Point: 256.7 °C
Enthalpy of Vaporization: 88.63 kJ/mol
Boiling Point: 500.9 °C at 760 mmHg
Vapour Pressure: 3.92E-12 mmHg at 25°C
Uses
1. Tricine (5704-04-1) is an organic compound that is used in buffer solution.
2.It is also used in resuspension of cell pellet.
Safety Profile
Hazard Codes: 
Xi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements :26-36-36/37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany: 3
F: 3