Reference

Determination of lower halogenated hydrocarbons by the water-xylene extraction method

Determination of lower halogenated hydrocarbons by the water-xylene extraction method. Inoko, Masanori; Tsuchiya, Masatoshi; Matsuno, Takeo (Inst. Environ. Sci. Technol., Yokohama Natl. Univ., Yokohama, Japan). Environ. Pollut., Ser. B, 7(2), 129-40 (English) 1984. CODEN: EPSPDH. ISSN: 0143-148X. DOCUMENT TYPE: Journal CA Section: 61 (Water) Section cross-reference(s): 80 A modified liq. extn. method for detg. trace amts. of lower halogenated hydrocarbons in drinking water has been studied. A 45 mL sample soln. contg. 35 mg/L of CHCl3 [67-66-3], CHBrCl2 [79-01-6], CHClBr2 [124-48-1], CHBr3 [75-25-2] and CCl2:CCl2 [127-18-4] and 0.4 mg/L of CCl4 [56-23-5] was extd. with 5 mL of xylene [1330-20-7]. The equil. concns. of lower halogenated hydrocarbons in the xylene phase were detd.In this experiment, several chemicals are used like 67-66-3 and 124-48-1 by a gas chromatog. equipped with an electron capture detector and using a column which consists of tricresylphosphate, squalane, and silicon DC 200. Lower halogenated hydrocarbons in drinking water were detd. successfully. .

Vestibulo-ocular disturbances in rats exposed to organic solvents

Vestibulo-ocular disturbances in rats exposed to organic solvents. Tham, R.; Bunnfors, I.; Eriksson, B.; Larsby, B.; Lindgren, S.; Odkvist, L. M. (Dep. Otorhinolaryngol., Linkoping Univ., Linkoping S-581 85, Swed.).Several reagents with their cas registry numbers 60-29-7 and 127-18-4 are used here. Acta Pharmacol. Toxicol., 54(1), 58-63 (English) 1984. CODEN: APTOA6. ISSN: 0001-6683. DOCUMENT TYPE: Journal CA Section: 4 (Toxicology) The influence of different kinds of industrial solvents on the vestibular function of rats was studied by recording nystagmus, induced by accelerated rotation. The effect was related to the blood levels of the solvents. One group of solvents, including halogenated satd. hydrocarbons like dichloromethane [75-09-2], caused depression of the vestibulo-oculomotor reflex (VOR). Another group, including benzene compds. like o-xylene [95-47-6], toluene [108-88-3], styrene [100-42-5], and cumene [98-82-8] and halogenated unsatd. hydrocarbons like 1,2-trichloroethylene [79-01-6], caused an excitation of the VOR. The most striking chem. similarity between the different solvents in the last group is the occurrence of double bonds. If the animals were exposed simultaneously to solvents from both groups, the excitatory effect prevailed and was even potentiated. Apparently, solvents cause depression or excitation of the VOR by interaction with central pathways in the reticular formation and the cerebellum. .