Detail of > 93106-60-6
- CAS Number:
- 93106-60-6
- Name:
Enrofloxacin
- Formula:
- C19H22FN3O3
- Molecular Structure:
- Synonyms:
- 1-Cyclopropyl-6-fluoro-7-(4-ethyl-1-piperazinyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylicacid;Alsir;BAY-Vp 2674;Baytril;Biofloxavet;CFPQ;Enrocin;Enrofan;Enrogil;Enroxil;N-Ethylciprofloxacin;N'-Ethylciprofloxacin;3-Quinolinecarboxylicacid, 1-cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-;
- Molecular Weight:
- 359.40
- Density:
- 1.385 g/cm3
- Melting Point:
- 225 °C
- Boiling Point:
- 560.5 °C at 760 mmHg
- Flash Point:
- 292.8 °C
- Appearance:
- Pale yellow crystals
- Hazard Symbols:
Xi- Risk Codes:
- 36/37/38
- Safety:
- 26-36/37Details
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Reference
- Preparation of quinolone and naphthylidinone N-oxides as antibacterials
- Preparation of quinolone and naphthylidinone N-oxides as antibacterials. Rast, Hubert; Scheer, Martin; Hallenbach, Werner (Bayer A.-G., Germany). Ger. Offen. DE 19519822 A1 5 Dec 1996, 14 pp. (German). (Germany). CODEN: GWXXBX. CLASS: ICM: C07D519-00. ICS: C07D241-52; C07D401-04; C07D295-24; C07D215-56; A61K031-47; A61K031-645. ICI: C07D519-00, C07D471-04, C07D471-08; C07D519-00, C07D471-04, C07D487-08; C07D519-00, C07D498-04, C07D487-08; C07D401-04, C07D215-56, C07D241-52; C07D471-04. 13721-01-2 and 93106-60-6 are also in the experiment. APPLICATION: DE 1995-19519822 31 May 1995. DOCUMENT TYPE: Patent CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Section cross-reference(s): 1, 5 Title compds. [I, II; X = H, halo, alkyl, alkoxy, NH2; Y = Q1-Q4; R1 = alkyl, cyclopropyl, 2-fluoroethyl, MeO, 4-fluorophenyl, 2,4-difluorophenyl, MeNH; R2 = H, (substituted) alkyl, cyclohexyl, PhCH2, 2-oxopropyl, phenacyl, EtO2CCH2, Me3CCO2CH2; R3 = H, Me, Et; R4 = (substituted) alkyl, cyclopropyl, acyl; R5 = H, Me, Ph, thienyl, pyridyl; R6-R8 = H, alkyl; A = N, CH, CMe, COMe, CX1; X1 = halo; B = O, (substituted) N, CH2; Z = CH, N], were prepd. Thus, enrofloxacin was refluxed 3-4 h with H2O2 in H2O to give 92.7% enrofloxacin N-oxide. This at 5 mg/kg in drinking water gave a fully effective blood level of enrofloxacin in calves. .
- Tissue distribution and depletion of enrofloxacin in rabbit
- Tissue distribution and depletion of enrofloxacin in rabbit.In this study，93106-60-6 is also used. Cagnardi, P.; Villa, R.; Sonzogni, O.; Carli, S. (Department of Veterinary Sciences and Technologies for Food Safety (VSA), Milan, Italy). Journal of Veterinary Pharmacology and Therapeutics, 26(Suppl. 1), 284 (English) 2003 Blackwell Publishing Ltd. CODEN: JVPTD9. ISSN: 0140-7783. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) Tissue distribution and depletion of enrofloxacin were studied in rabbits. The results indicated that a 48-h withdrawal time can be considered adequate. .
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