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1-ACETYL-2-ISONICOTINOYLHYDRAZINE

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Name

1-ACETYL-2-ISONICOTINOYLHYDRAZINE

EINECS N/A
CAS No. 1078-38-2 Density 1.231g/cm3
PSA 74.58000 LogP 1.09370
Solubility N/A Melting Point 158-159°C
Formula C8H9 N3 O2 Boiling Point 458.4°Cat760mmHg
Molecular Weight 179.20 Flash Point 231.1°C
Transport Information N/A Appearance N/A
Safety Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. Risk Codes N/A
Molecular Structure Molecular Structure of 1078-38-2 ((N)1-acetylisoniazid) Hazard Symbols N/A
Synonyms

Hydrazine,1-acetyl-2-isonicotinoyl- (7CI,8CI); Hydrazine, 1-acetyl-2-isonicotinyl- (6CI);1-Acetyl-2-isonicotinoylhydrazine; Acetylisoniazid; Acetylisoniazide;N-Acetyl-N'-isonicotinoylhydrazine; N-Acetylisoniazid;N-Acetylisonicotinylhydrazide; N-Monoacetylisoniazid; NSC 36084

Article Data 10

1-ACETYL-2-ISONICOTINOYLHYDRAZINE Chemical Properties

Molecular Formulat: C8H9N3O2
Molecular Weight: 179.17596 [g/mol]  
H-Bond Donort: 2
H-Bond Acceptot: 3
Rotatable Bond Countt: 1
Tautomer Countt: 5
Exact Masst of 1-ACETYL-2-ISONICOTINOYLHYDRAZINE (1078-38-2): 179.069477
MonoIsotopic Masst: 179.069477
Topological Polar Surface Areat: 71.1
Heavy Atom Countt: 13
Complexityt of 1-ACETYL-2-ISONICOTINOYLHYDRAZINE (1078-38-2): 200
Covalently-Bonded Unit Countt: 1

1-ACETYL-2-ISONICOTINOYLHYDRAZINE Toxicity Data With Reference

1.   

dni-mus-ipr 1 g/kg

   IJEBA6    Indian Journal of Experimental Biology. 19 (1981),939.
2. TYPE OF TEST: TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE: Oral
SPECIES OBSERVED: Rodent - mouse
DOSE/DURATION: 380 gm/kg/68W-C
TOXIC EFFECTS: Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors
REFERENCE: EJCAAH European Journal of Cancer.  (Oxford, UK)  V.1-17(6), 1965-1981. For publisher information, see EJCODS. Volume(issue)/page/year: 9,285,1973

1-ACETYL-2-ISONICOTINOYLHYDRAZINE Consensus Reports

EPA Genetic Toxicology Program.

1-ACETYL-2-ISONICOTINOYLHYDRAZINE Safety Profile

Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. When heated to decomposition 1-ACETYL-2-ISONICOTINOYLHYDRAZINE (1078-38-2) emits toxic fumes of NOx.
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