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1-Ethoxy-2-propanol

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Name

1-Ethoxy-2-propanol

EINECS 216-374-5
CAS No. 1569-02-4 Density 0.903 g/cm3
PSA 29.46000 LogP 0.40370
Solubility soluble Melting Point -100 °C
Formula C5H12O2 Boiling Point 131 °C at 760 mmHg
Molecular Weight 104.149 Flash Point 45.9 °C
Transport Information N/A Appearance Clear colorless liquid
Safety 24 Risk Codes 67-10
Molecular Structure Molecular Structure of 1569-02-4 (1-Ethoxy-2-propanol) Hazard Symbols R10:; R67:;
Synonyms

Ethyl Proxitol;NSC 2404;

Article Data 31

1-Ethoxy-2-propanol Synthetic route

64-17-5

ethanol

75-56-9, 16033-71-9

methyloxirane

1569-02-4

propylene glycol monoethyl ether

Conditions
ConditionsYield
With Al2O3/MgO composite at 120℃; Inert atmosphere;37.2%
With sodium ethanolate
With sodium hydroxide
64-67-5

diethyl sulfate

57-55-6

propylene glycol

1569-02-4

propylene glycol monoethyl ether

Conditions
ConditionsYield
at 90 - 100℃; in alkal.Loesung;
With sodium hydroxide at 100℃;
With sodium hydroxide at 100℃;
64-17-5

ethanol

75-56-9, 16033-71-9

methyloxirane

A

19089-47-5

2-ethoxy-1-propanol

B

1569-02-4

propylene glycol monoethyl ether

Conditions
ConditionsYield
With H+-Zeolite X at 35℃; for 24h; Product distribution; Mechanism; other 2-substituted epoxides; other alcohols, thiols and amine as nucleophiles; var. solid-catalysts; also H2SO4 as catalyst; var. temp.;
With sulfuric acid
With boron trifluoride
64-17-5

ethanol

141-52-6

sodium ethanolate

75-56-9, 16033-71-9

methyloxirane

1569-02-4

propylene glycol monoethyl ether

141-52-6

sodium ethanolate

75-56-9, 16033-71-9

methyloxirane

1569-02-4

propylene glycol monoethyl ether

Conditions
ConditionsYield
In ethanol
3054-95-3

acrylaldehyde diethyl acetal

A

16777-87-0

3,3-diethoxypropan-1-ol

B

1569-02-4

propylene glycol monoethyl ether

Conditions
ConditionsYield
With sodium hydroxide; dihydrogen peroxide; bis-(1,2-dimethylpropyl)borane Product distribution; 1)THF, 0 deg C, 7 h;A 90.5 % Chromat.
B 1 % Chromat.
64-17-5

ethanol

75-56-9, 16033-71-9

methyloxirane

A

1569-02-4

propylene glycol monoethyl ether

B

58797-30-1

di(propylene glycol) ethyl ether

Conditions
ConditionsYield
With sodium hydroxide Heating; Yield given. Yields of byproduct given;
64-17-5

ethanol

75-56-9, 16033-71-9

methyloxirane

sodium hydroxide

sodium hydroxide

1569-02-4

propylene glycol monoethyl ether

64-67-5

diethyl sulfate

57-55-6

propylene glycol

A

1569-02-4

propylene glycol monoethyl ether

B

propylene glycol-diethyl ether

propylene glycol-diethyl ether

23465-32-9

1-bromo-2-ethoxy-propane

A

19089-47-5

2-ethoxy-1-propanol

B

1569-02-4

propylene glycol monoethyl ether

Conditions
ConditionsYield
at 100℃;

1-Ethoxy-2-propanol Chemical Properties

Structure of 2-Propanol, 1-ethoxy- (CAS NO.1569-02-4):

IUPAC Name: 1-ethoxypropan-2-ol 
Empirical Formula: C5H12O2
Molecular Weight: 104.1476 
EINECS: 216-374-5 
Index of Refraction: 1.408
Molar Refractivity: 28.45 cm3
Molar Volume: 115.3 cm3
Polarizability: 11.27×10-24cm3
Surface Tension: 27.8 dyne/cm
Density: 0.903 g/cm3
Flash Point: 45.9 °C
Enthalpy of Vaporization: 42.95 kJ/mol 
Melting Point: -100 °C
Boiling Point: 131 °C at 760 mmHg
Vapour Pressure: 4.21 mmHg at 25°C 
Water Solubility: soluble 
Physical Appearance: Clear colorless liquid
Synonyms of 2-Propanol, 1-ethoxy- (CAS NO.1569-02-4): 1-Ethoxy-2-propanol ; 4-01-00-02471 (Beilstein Handbook Reference) ; Propylene glycol ethyl ether

1-Ethoxy-2-propanol Uses

  2-Propanol, 1-ethoxy- (CAS NO.1569-02-4) is used in coatings, inks, photosensitive plastic etc.

1-Ethoxy-2-propanol Toxicity Data With Reference

1.    

orl-rat LD50:4400 mg/kg

    NPIRI*    Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. 1 (1974),104.
2.    

skn-rbt LD50:8100 mg/kg

    NPIRI*    Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. 1 (1974),104.

1-Ethoxy-2-propanol Consensus Reports

Glycol ether compounds are on the Community Right-To-Know List.

1-Ethoxy-2-propanol Safety Profile

Mildly toxic by ingestion and skin contact. A combustible liquid. When heated to decomposition it emits acrid smoke and irritating fumes. See also GLYCOL ETHERS.
Risk Statements: 67-10 
R67:Vapours may cause drowsiness and dizziness. 
R10:Flammable.
Safety Statements: 24 
S24:Avoid contact with skin.
RIDADR: 1987
RTECS: UB5250000
HazardClass: 3
PackingGroup: III

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