1-Ethoxy-2-propanol

Base Information

• Chemical Name: 1-Ethoxy-2-propanol
• CAS No.: 1569-02-4
• Molecular Formula: C5H12O2
• Molecular Weight: 104.149
• Hs Code.: 29094990
• European Community (EC) Number: 216-374-5
• ICSC Number: 1573
• NSC Number: 2404
• UN Number: 1993
• UNII: ROT9EQO32E
• DSSTox Substance ID: DTXSID1041267
• Nikkaji Number: J13.130J
• Wikidata: Q27288224
• ChEMBL ID: CHEMBL3188294
• Mol file: 1569-02-4.mol

Synonyms:Ethyl Proxitol;NSC 2404;

Chemical Property of 1-Ethoxy-2-propanol

Chemical Property:

• Appearance/Colour: Clear colorless liquid
• Vapor Pressure: 4.21mmHg at 25°C
• Melting Point: -100 °C
• Refractive Index: 1.405-1.409
• Boiling Point: 131 °C at 760 mmHg
• PKA: 14.51±0.20(Predicted)
• Flash Point: 45.9 °C
• PSA: 29.46000
• Density: 0.903 g/cm³
• LogP: 0.40370
• Storage Temp.: Flammables area
• Solubility.: Chloroform (Sparingly), Ethyl Acetate (Slightly)
• Water Solubility.: soluble
• XLogP3: 0.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 104.083729621
• Heavy Atom Count: 7
• Complexity: 37.1

Purity/Quality:

99.0% ^*data from raw suppliers

1-Ethoxy-2-propanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R10:; R67:
• Hazard Codes: R10:; R67:
• Statements: 67-10
• Safety Statements: 24

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Solvents -> Glycol Ethers (P Series)
• Canonical SMILES: CCOCC(C)O
• Inhalation Risk: No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20 °C.
• Effects of Short Term Exposure: The substance is mildly irritating to the eyes.
• Uses: 1-Ethoxy-2-propanol is used as a solvent for a wide variety of resins such as epoxies, acrylic, alkyds, polyesters, nitrocellulose, and polyurethanes. It is also used in the surface coating and printing industries, thereby it regulate the flow, levelling, and coalescence of both surface coatings. It acts as an intermediate in the production of agro-chemicals and de-icing, and anti-icing formulations. It finds application as to make cleaning products, as grease and paint remover.

Technology Process of 1-Ethoxy-2-propanol

There total 13 articles about 1-Ethoxy-2-propanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.2%

ethanol (64-17-5) + methyloxirane (75-56-9,16033-71-9) → propylene glycol monoethyl ether (1569-02-4)

Guidance literature:

With Al₂O₃/MgO composite; at 120 ℃; Inert atmosphere;

DOI:10.1016/j.apcata.2011.09.010

Reference yield:

ethanol (64-17-5) + isopropyl alcohol (67-63-0,8013-70-5) + methyloxirane (75-56-9,16033-71-9) + tert-butyl alcohol (75-65-0) → propylene glycol monoethyl ether (1569-02-4) + 1-isopropoxy-2-propanol (3944-36-3) + 1-tert-butoxy-2-propanol (57018-52-7)

Guidance literature:

Trimethyl borate; hydrogen fluoride; In water; for 0.5h;

Reference yield:

1-ethoxy-2-propanyl formate → formic acid (64-18-6) + propylene glycol monoethyl ether (1569-02-4)

Guidance literature:

With water; at 80 ℃; for 24h; Equilibrium constant; Sealed tube;

upstream raw materials:

diethyl sulfate

propylene glycol

ethanol

methyloxirane

Downstream raw materials:

2-acetoxy-1-ethoxypropane

Thiophosphoric acid O-(2-ethoxy-1-methyl-ethyl) ester O'-methyl ester O''-(4-methylsulfanyl-phenyl) ester

Thiophosphoric acid O-(2-ethoxy-1-methyl-ethyl) ester O'-methyl ester O''-(3-methyl-4-methylsulfanyl-phenyl) ester

Thiophosphoric acid O-(2-ethoxy-1-methyl-ethyl) ester O'-ethyl ester O''-(4-methylsulfanyl-phenyl) ester