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Name	2-(Trifluoromethyl)phenothiazine	EINECS	202-145-7
CAS No.	92-30-8	Density	1.369 g/cm³
PSA	37.33000	LogP	5.05160
Solubility	N/A	Melting Point	188-190 °C(lit.)
Formula	C₁₃H₈F₃NS	Boiling Point	361.1 °C at 760 mmHg
Molecular Weight	267.274	Flash Point	172.2 °C
Transport Information	N/A	Appearance	yellow to green powder
Safety	36	Risk Codes	20/21/22
Molecular Structure		Hazard Symbols	Xn,Xi
Synonyms	Phenothiazine,2-(trifluoromethyl)- (6CI,7CI,8CI);NSC 50438;	Article Data	19

2-(Trifluoromethyl)phenothiazine Chemical Properties

IUPAC Name: 2-(trifluoromethyl)-10H-phenothiazine
MF: C₁₃H₈F₃NS
MW: 267.27
EINECS: 202-145-7
Appearance:Light yellow-green powder
Melting point: 188-190 °C(lit.)
Boiling Point: 361.1 °C at 760 mmHg
Flash Point: 172.2 °C
Density: 1.369 g/cm³
Vapour Pressure: 2.12E-05 mmHg at 25°C
Following is the Molecular Structure of 2-(Trifluoromethyl)phenothiazine (92-30-8):

2-(Trifluoromethyl)phenothiazine Uses

2-(Trifluoromethyl)phenothiazine (92-30-8) can be used as Intermediates of Trifluoperazine hydrochloride .

2-(Trifluoromethyl)phenothiazine Production

2-(Trifluoromethyl)phenothiazine (92-30-8) can be produced as following: With 2-carboxy-3-(trifluoromethyl) diphenylamine (synthetic antibacterial agent Montelukast acid) by the high-temperature catalytic decarboxylation (200 ° C, iron powder), generating 3-(Trifluoromethyl) diphenylamine . Then take the 3-(Trifluoromethyl) diphenylamine heating with sulfur with the participation of iodine . After the cyclization,can obtain 2-(Trifluoromethyl)phenothiazine (92-30-8).

2-(Trifluoromethyl)phenothiazine Toxicity Data With Reference

1.		orl-mus LD50:520 mg/kg		TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Sciences. 12 (1971),110.
2.		ivn-mus LD50:32 mg/kg		CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) NX#07426 .

2-(Trifluoromethyl)phenothiazine Consensus Reports

Reported in EPA TSCA Inventory.

2-(Trifluoromethyl)phenothiazine Safety Profile

Poison by intravenous route. Moderately toxic by ingestion. When heated to decomposition it emits toxic vapors of NO_x and F⁻.

Other safty informations about
Hazard Codes :Xn(Harmful),Xi (Irritant)
Risk Statements :20/21/22
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements :36
S36:Wear suitable protective clothing
WGK Germany :3
RTECS: SP5620000

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