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Name |
2-Amino-1,3-thiazole-5-carboxylic acid |
EINECS | N/A |
CAS No. | 40283-46-3 | Density | 1.657 g/cm3 |
PSA | 104.45000 | LogP | 1.00470 |
Solubility | N/A | Melting Point |
214-216 °C |
Formula | C4H4N2O2S | Boiling Point | 415 °C at 760 mmHg |
Molecular Weight | 144.154 | Flash Point | 204.8 °C |
Transport Information | N/A | Appearance | N/A |
Safety | Risk Codes | N/A | |
Molecular Structure | Hazard Symbols | Xi | |
Synonyms |
2-Amino-5-thiazolecarboxylicacid;NSC 239729; |
Article Data | 6 |
2-amino-thiazole-5-carboxylic acid ethyl ester
2-aminothiazole-5-carboxylic acid
Conditions | Yield |
---|---|
With sodium hydroxide In tetrahydrofuran; water Reflux; | 86% |
With sodium hydroxide | |
With barium dihydroxide | |
With potassium hydroxide In methanol |
methyl 2-aminothiazole-5-carboxylate
2-aminothiazole-5-carboxylic acid
Conditions | Yield |
---|---|
With sodium hydroxide Ambient temperature; | 74% |
2-acetylamino-thiazole-5-carbonitrile
2-aminothiazole-5-carboxylic acid
Conditions | Yield |
---|---|
With hydrogenchloride |
2-aminothiazole-5-carboxylic acid
acetic anhydride
2-(acetylamino)thiazole-5-carboxylic acid
Conditions | Yield |
---|---|
With pyridine at 20 - 130℃; | 71% |
2-aminothiazole-5-carboxylic acid
5-fluoro-1,3-thiazol-2-amine hydrochloride
Conditions | Yield |
---|---|
Stage #1: 2-aminothiazole-5-carboxylic acid With potassium phosphate In 1,4-dioxane; methanol; toluene at 20℃; for 2h; Stage #2: With 1-(chloromethyl)-4-fluoro-1,4-diazabicyclo[2.2.2]octane-1,4-diium tetrafluoroborate In 1,4-dioxane; methanol; toluene at 20℃; for 0.5h; Stage #3: With hydrogenchloride In 1,4-dioxane; methanol; toluene Product distribution / selectivity; | 69% |
Conditions | Yield |
---|---|
In ethanol for 6h; Reflux; | 44% |
2-aminothiazole-5-carboxylic acid
dibenzylamine
Conditions | Yield |
---|---|
Stage #1: 2-aminothiazole-5-carboxylic acid With 4-methyl-morpholine; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate In N,N-dimethyl-formamide at 0℃; for 0.5h; Stage #2: dibenzylamine In N,N-dimethyl-formamide at 20℃; | 41% |
2-aminothiazole-5-carboxylic acid
(aminomethyl)cyclopropane hydrochloride
N-cyclopropylmethyl-2-aminothiazole-5-carboxamide
Conditions | Yield |
---|---|
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine In N,N-dimethyl-formamide at 20℃; |
2-aminothiazole-5-carboxylic acid
1-cyclopentylethyl amine hydrochloride
N-(1-cyclopentylethyl)-2-aminothiazole-5-carboxamide
Conditions | Yield |
---|---|
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine In N,N-dimethyl-formamide at 20℃; |
2-aminothiazole-5-carboxylic acid
N-cyclopentylmethyl-2-aminothiazole-5-carboxamide
Conditions | Yield |
---|---|
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine In N,N-dimethyl-formamide at 20℃; |
IUPAC Name: 2-Amino-1,3-thiazole-5-carboxylic acid
Systematic of 5-Thiazolecarboxylicacid, 2-amino- (CAS NO.40283-46-3): 2-Amino-5-thiazolecarboxylic acid ; 2-Aminothiazole-5-carboxylic acid ; 2-Aminothiazol-5-ylcarboxylic acid ; Rarechem al be 1263 ; 2-Amino-1,3-thiazole-5-carboxylic acid ; 2-Amino-1,3-thiazole-5-carboxylic acid 98%
CAS NO: 40283-46-3
Molecular Formula of 5-Thiazolecarboxylicacid, 2-amino- (CAS NO.40283-46-3): C4H4N2O2S
Molecular Weight: 144.1518
Molecular Structure:
Melting Point: 214-216°C
ProductCategories: Amines ; blocks ; Carboxes ; Thiazoles
H bond acceptors: 4
H bond donors: 3
Freely Rotating Bonds: 1
Polar Surface Area: 70.67 Å2
Index of Refraction: 1.707
Molar Refractivity: 33.89 cm3
Molar Volume: 86.9 cm3
Surface Tension: 96.5 dyne/cm
Density of 5-Thiazolecarboxylicacid, 2-amino- (CAS NO.40283-46-3): 1.657 g/cm3
Flash Point: 204.8 °C
Enthalpy of Vaporization: 70.43 kJ/mol
Boiling Point: 415 °C at 760 mmHg
Vapour Pressure: 1.25E-07 mmHg at 25°C
Hazard Codes: Xi
Hazard Note: Irritant/Keep Cold