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Name	2-Amino-5-diethylaminopentane	EINECS	205-435-1
CAS No.	140-80-7	Density	0.817
PSA	29.26000	LogP	2.15590
Solubility	N/A	Melting Point	37.5°C (estimate)
Formula	C9H22 N2	Boiling Point	200.5 °C at 760 mmHg
Molecular Weight	158.287	Flash Point	155 ºF
Transport Information	UN 2946	Appearance	Colorless clear liquid
Safety	Poison by intravenous route. When heated to decomposition it emits toxic vapors of NO_x.	Risk Codes	R34
Molecular Structure		Hazard Symbols
Synonyms	1-(Diethylamino)-4-aminopentane;1-Methyl-4-(diethylamino)butylamine;2-Amino-5-(diethylamino)pentane;2-Amino-5-diethylamino-n-pentane;4-(Diethylamino)-1-methylbutylamine;4-Amino-1-(diethylamino)pentane;5-(Diethylamino)-2-pentanamine;5-(Diethylamino)-2-pentylamine;N,N-Diethyl-1,4-pentanediamine;N1,N1-Diethyl-1,4-pentanediamine;N5,N5-Diethyl-2,5-pentanediamine;NSC 2606;Novoldiamine;d-(Diethylamino)-a-methylbutylamine;

2-Amino-5-diethylaminopentane Synthetic route

: 67459-50-1
(R)-(-)-4-amino-1-(diethylamino)pentane

: 140-80-7
5-diethylamino-2-pentylamine

Conditions

Conditions	Yield
With nickel In toluene at 70℃; for 12h;	97.2%

: 5412-69-1
5-diethylaminopentan-2-ol

: 140-80-7
5-diethylamino-2-pentylamine

Conditions

Conditions	Yield
With ammonia; nickel at 200℃; unter Druck;
With ammonia; nickel at 200℃; unter Druck;

: 39749-10-5
diethyl-(4-chloro-pentyl)-amine

A: 344325-82-2
N1,N1-diethyl-1-methyl-butanediyldiamine

B: 140-80-7
5-diethylamino-2-pentylamine

Conditions

Conditions	Yield
With potassium phthalide; xylene at 150 - 160℃; anschl. Erwaermen mit HCl;

: 105-14-6
5-diethylamino-2-pentanone

: 140-80-7
5-diethylamino-2-pentylamine

Conditions

Conditions	Yield
With methanol; ammonia; nickel at 95 - 96℃; under 36775.4 Torr; Hydrogenation;
With ethanol; ammonia at 40℃;
Multi-step reaction with 2 steps 1: ethanol; Raney nickel; NH3 / Hydrogenation 2: methanol; nickel catalyst; hydrogen; NH3 / 14710.2 Torr View Scheme
With methanol; ammonia; nickel at 70 - 80℃; Hydrogenation.unter Druck;

: 105-14-6
5-diethylamino-2-pentanone

A: 101881-56-5
bis-(4-diethylamino-1-methyl-butyl)-amine

B: 140-80-7
5-diethylamino-2-pentylamine

Conditions

Conditions	Yield
With ethanol; ammonia at 20℃;
With ethanol; ammonia; nickel Hydrogenation;

: 5426-96-0
5-diethylamino-pentan-2-one oxime

: 140-80-7
5-diethylamino-2-pentylamine

Conditions

Conditions	Yield
With ethanol; sodium

: 101881-56-5
bis-(4-diethylamino-1-methyl-butyl)-amine

: 140-80-7
5-diethylamino-2-pentylamine

Conditions

Conditions	Yield
With methanol; ammonia; hydrogen; nickel under 14710.2 Torr;

: 7647-01-0
hydrogenchloride

: 491-92-9
pamaquine

: 7732-18-5
water

NaNO2: NaNO2

A: 477601-28-8
6-methoxy-quinolin-8-ol

B: 140-80-7
5-diethylamino-2-pentylamine

Conditions

Conditions	Yield
anschl. mit methanol. KOH;

...Expand

: 67-56-1
methanol

: 101881-56-5
bis-(4-diethylamino-1-methyl-butyl)-amine

: 7664-41-7
ammonia

hydrogen: hydrogen

nickel catalyst: nickel catalyst

: 140-80-7
5-diethylamino-2-pentylamine

Conditions

Conditions	Yield
under 14710.2 Torr;

...Expand

: 105-14-6
5-diethylamino-2-pentanone

: 7664-41-7
ammonia

nickel: nickel

: 140-80-7
5-diethylamino-2-pentylamine

Conditions

Conditions	Yield
Hydrogenation;

2-Amino-5-diethylaminopentane Chemical Properties

Molecular Formula: C₉H₂₂N₂
Molecular Weight: 158.28
EINECS: 205-435-1
Boiling point: 101 °C / 37mmHg
Density: 0.817 g/mL at 25 °C(lit.)
Refractive index: n20/D 1.4429(lit.)
Flash point: 155 °F
Merck: 6723
N,N-Diethyl-4-Methyltetramethylene-Diamine's(140-80-7) Synonyms: 1-(Diethylamino)-4-aminopentane;1-Diethylamino-4-aminopentane;1-Methyl-4-(diethylamino)butylamine;1-Methyl-4-dietylaminobutylamine;4-(Diethylamino)-1-methylbutylamine;4-Pentanediamine,N’,N’-diethyl-1;5-(Diethylamino)-2-pentylamine;delta-(Diethylamino)-alpha-methylbutylamine
N,N-Diethyl-4-Methyltetramethylene-Diamine's(140-80-7) structural formula:

2-Amino-5-diethylaminopentane Toxicity Data With Reference

ivn-mus LD50:180 mg/kg

CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) NX#05228 .

2-Amino-5-diethylaminopentane Consensus Reports

Reported in EPA TSCA Inventory.

2-Amino-5-diethylaminopentane Safety Profile

Poison by intravenous route. When heated to decomposition it emits toxic vapors of NO_x.

Safety Information for N,N-Diethyl-4-Methyltetramethylene-Diamine(140-80-7)
Hazard Codes C
Risk Statements 34
Safety Statements 26-36/37/39-45
RIDADR UN 2946 6.1/PG 3
WGK Germany 1
RTECS XE1900000
HazardClass 8
PackingGroup III

2-Amino-5-diethylaminopentane Specification

Accidental Release Measures for N,N-Diethyl-4-Methyltetramethylene-Diamine(140-80-7)
【Small spills/leaks】Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Attempt to stop leak if without undue personnel hazard.

N,N-Diethyl-4-Methyltetramethylene-Diamine's(140-80-7) Stability and Reactivity
【Incompatibilities】Incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides.
【Combustion Products】Fire may produce irritating, corrosive and/or toxic gases.

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