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140-82-9

Basic Information
CAS No.: 140-82-9
Name: 2-(2-(Diethylamino)ethoxy)ethanol
Article Data: 13
Cas Database
Molecular Structure:
Molecular Structure of 140-82-9 (2-(2-(Diethylamino)ethoxy)ethanol)
Formula: C8H19NO2
Molecular Weight: 161.244
Synonyms: Ethanol,2-(b-diethylaminoethoxy)- (3CI);2-(b-Diethylamino)ethoxyethanol;2-[2-(Diethylamino)ethoxy]ethanol;2-[2-(N,N-Diethylamino)ethoxy]ethanol;Diethyl[2-(2-hydroxyethoxy)ethyl]amine;NSC 163322;
EINECS: 205-436-7
Density: 0.939 g/cm3
Melting Point: N/A
Boiling Point: 234.7 °C at 760 mmHg
Flash Point: 95.8 °C
Solubility: N/A
Appearance: colorless or light yellow liquid
Hazard Symbols: C
Risk Codes: 34
Safety: 23-24/25
Transport Information: N/A
PSA: 32.70000
LogP: 0.33710
Synthetic route
118591-58-5

5-tosyloxy-3-oxapentanol

109-89-7

diethylamine

140-82-9

2-[2-(diethylamino)ethoxy] ethanol

Conditions
ConditionsYield
With potassium carbonate In 1,4-dioxane at 70℃;42%
75-21-8

oxirane

100-37-8

2-(Diethylamino)ethanol

140-82-9

2-[2-(diethylamino)ethoxy] ethanol

Conditions
ConditionsYield
at 100℃;
at 100℃;
628-89-7

2-(2-Chloroethoxy)ethanol

109-89-7

diethylamine

140-82-9

2-[2-(diethylamino)ethoxy] ethanol

14258-40-3

2-(2-chloroethoxy)ethyl ethanoate

109-89-7

diethylamine

140-82-9

2-[2-(diethylamino)ethoxy] ethanol

Conditions
ConditionsYield
With ethanol at 125℃;
114188-38-4

Methyl-N,N-diethyldiglycollamat

140-82-9

2-[2-(diethylamino)ethoxy] ethanol

Conditions
ConditionsYield
With lithium aluminium tetrahydride
100-37-8

2-(Diethylamino)ethanol

107-07-3

2-chloro-ethanol

140-82-9

2-[2-(diethylamino)ethoxy] ethanol

Conditions
ConditionsYield
With sodium
100-35-6

2-(diethylamino)ethyl chloride

monosodium compound of ethylene glycol

monosodium compound of ethylene glycol

140-82-9

2-[2-(diethylamino)ethoxy] ethanol

Conditions
ConditionsYield
With benzene

A

5465-28-1

α-Ethyl-α-phenylbutyric acid

B

140-82-9

2-[2-(diethylamino)ethoxy] ethanol

Conditions
ConditionsYield
With sodium hydroxide at 100℃; for 3h;
75-07-0

acetaldehyde

929-06-6

2-(2-Aminoethoxy)ethanol

140-82-9

2-[2-(diethylamino)ethoxy] ethanol

Conditions
ConditionsYield
With NaBH3CN In methanol; water
With NaBH3CN In methanol; water
52835-16-2

2-Heptadecafluorooctyl-oxirane

140-82-9

2-[2-(diethylamino)ethoxy] ethanol

99679-36-4

N,N-diethyl hydroxy-8 F-octyl-8 dioxa-3,6 octylamine

Conditions
ConditionsYield
With sodium at 80 - 100℃;60%
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Chemistry

Chemical Name: 6-Ethyl-3-oxa-6-azaoctanol
IUPAC NAME: 2-(2-diethylaminoethyloxy)ethanol
CAS No.: 140-82-9
EINECS: 205-436-7
Molecular Formula: C8H19NO2
Molecular Weight: 161.24 g/mol
Density: 0.939 g/cm3
Melting Point: 101°C
Flash Point: 95.8 °C
Boiling Point: 234.7 °C at 760 mmHg
Following is the structure of 2-(2-(DIETHYLAMINO)ETHOXY)ETHANOL(140-82-9):

                 
The chemical synonymous of 2-(2-(DIETHYLAMINO)ETHOXY)ETHANOL(140-82-9) are 2-(2-(diethylamino)ethoxy)-ethano;2-(beta-(diethylamino)ethoxy)ethanol;2-[2-(diethylamino)ethoxy]-ethano;2-beta-Diethylaminoethoxyethanol;beta-(Diethylamino ethoxy)ethanol;Diethylaminoethoxyethanol;diethylaminoethoxyethanol,[combustibleliquidlabel];diethylaminoethoxyethanol,[flammableliquidlabel].

Uses

2-(2-(DIETHYLAMINO)ETHOXY)ETHANOL(140-82-9) is mainly used for the production of antitussives carbetapentane.

Production

Product Categories about 2-(2-(DIETHYLAMINO)ETHOXY)ETHANOL(140-82-9) are Alkohols;Ethylene Glycols & Monofunctional Ethylene Glycols;Monofunctional Ethylene Glycols.

Toxicity Data With Reference

1.    

skn-rbt 10 µL MLD open

    NTIS**    National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) OTS0535166 .
2.    

eye-rbt 5 µL/24H SEV

    NTIS**    National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) OTS0535166 .
     

 

     
     

 

     
rabbit LD50 skin 2020uL/kg (2.02mL/kg) GASTROINTESTINAL: OTHER CHANGES

LIVER: OTHER CHANGES

SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
National Technical Information Service. Vol. OTS0535166,
rat LD50 oral 2590uL/kg (2.59mL/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

GASTROINTESTINAL: OTHER CHANGES
National Technical Information Service. Vol. OTS0535166,

Safety Profile

A poison by ingestion and skin contact. A severe eye and mild skin irritant. When heated to decomposition it emits toxic vapors of NOx.
Safety Statements about 2-(2-(DIETHYLAMINO)ETHOXY)ETHANOL(140-82-9):
    S23 Do not breathe vapour.
    S24/25: Avoid contact with skin and eyes.
Health Hazard: Inhalation or contact with material may irritate or burn skin and eyes. Fire may produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control may cause pollution.
Fire Hazard: HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

Specification

Reactivity Profile: 6-Ethyl-3-oxa-6-azaoctanol is an amine and alcohol. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.