Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

4-Piperidinopiperidine
Related Products

Hot Products

Basic Information Post buying leads Suppliers Cas Database
Name

4-Piperidinopiperidine

 EINECS 225-522-8
CAS No. 4897-50-1 Density 0.969 g/cm3
PSA 15.27000 LogP 1.49100
Solubility N/A Melting Point 64-66 °C(lit.)
Formula C10H20N2 Boiling Point 251.4 °C at 760 mmHg
Molecular Weight 168.282 Flash Point 99.9 °C
Transport Information N/A Appearance light yellow to yellow-brown crystalline solid
Safety 24/25-26-36 Risk Codes 36/37/38
Molecular Structure Molecular Structure of 4897-50-1 (4-Piperidinopiperidine) Hazard Symbols IrritantXi
Synonyms

1,4-Bipiperidyl;1,4'-bipiperidine;1-(3,4,5,6-tetrahydro-2H-pyridin-4-yl)-3,4,5,6-tetrahydro-2H-pyridine;4-(1-piperidinyl)piperidine;[1,4']Bipiperidinyl;4-(1-Piperidino)piperidine;1-(4-piperidyl)piperidine;

Article Data 6

4-Piperidinopiperidine Synthetic route

110-89-4

piperidine

79099-07-3

N-tert-butyloxycarbonylpiperidin-4-one

4897-50-1

4-piperidinopiperidin

Conditions
ConditionsYield
With sodium tris(acetoxy)borohydride; acetic acid In dichloromethane at 0 - 20℃; for 16h;80%
383865-57-4

4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl-amine

A

4897-50-1

4-piperidinopiperidin

B

[1,4']Bipiperidinyl-1'-carboxylic acid (4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide

Conditions
ConditionsYield
A n/a
B 35%
97682-44-5, 130144-33-1

irinotecan

A

4897-50-1

4-piperidinopiperidin

B

86639-52-3, 110714-48-2, 130144-34-2

7-ethyl-10-hydroxycamptothecin

Conditions
ConditionsYield
With carboxylesterase at 37℃; for 0.0833333h; pH=7.4;
944411-93-2

[1,4']bipiperidinyl-1'-carboxylic acid (4-bromo-phenyl)amide

A

4897-50-1

4-piperidinopiperidin

B

[1,4']bipiperidinyl-1'-carboxylic acid (3'-acetylamino-biphenyl-4-yl)amide

C

1608129-84-5

C14H14N2O

D

106-40-1

4-bromo-aniline

Conditions
ConditionsYield
Suzuki-Miyaura Coupling;
79099-07-3

N-tert-butyloxycarbonylpiperidin-4-one

4897-50-1

4-piperidinopiperidin

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: acetic acid; sodium tris(acetoxy)borohydride / dichloromethane / 16 h / 0 - 20 °C
2: hydrogenchloride / methanol / 12 h / 40 °C
View Scheme
125541-12-0

tert-butyl 1,4’-bipiperidine-1’-carboxylate

4897-50-1

4-piperidinopiperidin

Conditions
ConditionsYield
With hydrogenchloride In methanol at 40℃; for 12h;2.04 g
4897-50-1

4-piperidinopiperidin

2369-11-1

5-fluoro-2-nitroaniline

900506-32-3

2-nitro-5-(4-(piperidin-1-yl)piperidin-1-yl)benzenamine

Conditions
ConditionsYield
With triethylamine In 1-methyl-pyrrolidin-2-one at 100℃; for 2.5h;100%
With N-ethyl-N,N-diisopropylamine In 1-methyl-pyrrolidin-2-one at 120℃; for 4h;75%
4897-50-1

4-piperidinopiperidin

5147-80-8

[Bis(methylthio)methylene]malononitrile

904677-87-8

[(methylthio)(4-piperidinopiperidino)methylene]malononitrile

Conditions
ConditionsYield
In tetrahydrofuran at 0 - 20℃; for 0.25h;100%
4897-50-1

4-piperidinopiperidin

185321-62-4

2-tert-butyloxycarbonylamino-3-(3,4-dichlorophenyl)propionic acid

C24H35Cl2N3O3

Conditions
ConditionsYield
With benzotriazol-1-ol; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide100%
4897-50-1

4-piperidinopiperidin

215595-66-7

N6-Boc-N2-Cbz-lysine

C29H46N4O5

Conditions
ConditionsYield
100%

4-Piperidinopiperidine Specification

The 4-Piperidinopiperidine, with the CAS registry number 4897-50-1, is also known as 1,4'-Bipiperidin. It belongs to the product categories of Nitrogen Cyclic Compounds; Pharmaceutical Intermediates; Heterocycles; Piperidine; Heterocyclic Compounds; Piperidine Series; Piperidines. Its EINECS registry number is 225-522-8. This chemical's molecular formula is C10H20N2 and molecular weight is 168.2792. Its IUPAC name is called 1-piperidin-4-ylpiperidine. What's more, the product should be sealed and stored in cool and dry place.

Physical properties of 4-Piperidinopiperidine: (1)ACD/LogP: 1.53; (2)ACD/LogD (pH 5.5): -2.57; (3)ACD/LogD (pH 7.4): -2.18; (4)ACD/BCF (pH 5.5): 1; (5)ACD/BCF (pH 7.4): 1; (6)ACD/KOC (pH 5.5): 1; (7)ACD/KOC (pH 7.4): 1; (8)#H bond acceptors: 2; (9)#H bond donors: 1; (10)#Freely Rotating Bonds: 1; (11)Index of Refraction: 1.5; (12)Molar Refractivity: 51.07 cm3; (13)Molar Volume: 173.6 cm3; (14)Surface Tension: 35.5 dyne/cm; (15)Density: 0.969 g/cm3; (16)Flash Point: 99.9 °C; (17)Enthalpy of Vaporization: 48.88 kJ/mol; (18)Boiling Point: 251.4 °C at 760 mmHg; (19)Vapour Pressure: 0.0205 mmHg at 25°C.

Uses of 4-Piperidinopiperidine: it can be used to produce 4-Oxo-4-phenyl-2-(4-piperidinopiperidino)-butansaeure with 4-oxo-4-phenyl-but-2-enoic acid. This reaction will need solvents toluene and ethanol. The yield is about 68%.

4-Piperidinopiperidine can be used to produce 4-Oxo-4-phenyl-2-(4-piperidinopiperidino)-butansaeure with 4-oxo-4-phenyl-but-2-enoic acid

When you are using this chemical, please be cautious about it as the following:
This chemical may cause inflammation to the skin or other mucous membranes. It is irritating to eyes, respiratory system and skin. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. Whenever you will contact it, please wear suitable protective clothing.

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: C1CCN(CC1)C2CCNCC2
(2)InChI: InChI=1S/C10H20N2/c1-2-8-12(9-3-1)10-4-6-11-7-5-10/h10-11H,1-9H2
(3)InChIKey: QDVBKXJMLILLLB-UHFFFAOYSA-N

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 4897-50-1