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Acetamide, N-ethenyl-

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Name

Acetamide, N-ethenyl-

EINECS 225-989-8
CAS No. 5202-78-8 Density 0.89g/cm3
PSA 29.10000 LogP 0.65690
Solubility Soluble in water Melting Point 51-54 °C(lit.)
Formula C4H7NO Boiling Point 207.7 °C at 760 mmHg
Molecular Weight 85.1057 Flash Point 103.6 °C
Transport Information N/A Appearance N/A
Safety 26-36 Risk Codes 22-36/38
Molecular Structure Molecular Structure of 5202-78-8 (N-VINYLACETAMIDE  97) Hazard Symbols HarmfulXn
Synonyms

Acetamide,N-vinyl- (6CI,7CI,8CI);N-Vinylacetamide;NVA;Vinylacetamide;N-Ethenylacetamide;

Article Data 24

Acetamide, N-ethenyl- Synthetic route

142-26-7

2-acetylaminoethanol

5202-78-8

acetylaminoethylene

Conditions
ConditionsYield
With succinic acid anhydride at 40 - 75℃; for 15h; Time; Inert atmosphere;82.2%
55204-51-8

N-(1-methoxyethyl)acetamide

5202-78-8

acetylaminoethylene

Conditions
ConditionsYield
at 550℃;70%
at 440℃; under 100 Torr;
69773-71-3

2-methyl-4-methyl-4H-oxazolin-5-one

5202-78-8

acetylaminoethylene

Conditions
ConditionsYield
at 550℃; under 0.1 - 0.2 Torr;32%
7355-58-0

N-(2-chloro-ethyl)-acetamide

5202-78-8

acetylaminoethylene

Conditions
ConditionsYield
With sodium hydroxide; hexane
With sodium hydroxide; hexane
With sodium hydroxide; hexane
5335-91-1

1,1-bis-acetylamino-ethane

5202-78-8

acetylaminoethylene

Conditions
ConditionsYield
at 220℃;
19861-71-3

N-(1-cyanoethyl)acetamide

5202-78-8

acetylaminoethylene

Conditions
ConditionsYield
at 450℃; under 13 Torr;
58286-92-3

C18H17NO

A

5202-78-8

acetylaminoethylene

B

120-12-7

anthracene

Conditions
ConditionsYield
In diphenylether at 250℃; Rate constant;
60-35-5

acetamide

542-10-9

ethylidene diacetate

A

5335-91-1

1,1-bis-acetylamino-ethane

B

625-77-4

N-acetylacetamide

C

5202-78-8

acetylaminoethylene

Conditions
ConditionsYield
With caesium carbonate In acetonitrile at 50℃; for 3h;A 12.1 % Chromat.
B 17.2 % Chromat.
C 23.8 % Chromat.
60-35-5

acetamide

542-10-9

ethylidene diacetate

A

5335-91-1

1,1-bis-acetylamino-ethane

B

625-77-4

N-acetylacetamide

C

5202-78-8

acetylaminoethylene

D

N-(1-Acetylamino-ethyl)-N-vinyl-acetamide

Conditions
ConditionsYield
With caesium carbonate In acetonitrile at 50℃; for 3h; Product distribution; reactions in presence of further bases or Lewis acids;A 12.1 % Chromat.
B 17.2 % Chromat.
C 23.8 % Chromat.
D 1.6 % Chromat.

N-(α-isopropoxyethyl)acetamide

5202-78-8

acetylaminoethylene

Acetamide, N-ethenyl- Specification

The Acetamide, N-ethenyl-, with CAS registry number 5202-78-8,  has the systematic name of N-ethenylacetamide. Besides this, it is also called N-Vinylacetamide 97. And the chemical formula of this chemical is C4H7NO. What's more, its EINECS is 225-989-8.

Physical properties of Acetamide, N-ethenyl-: (1)ACD/LogP: 0.00; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0; (4)ACD/LogD (pH 7.4): 0; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 23.81; (8)ACD/KOC (pH 7.4): 23.81; (9)#H bond acceptors: 2; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 1; (12)Polar Surface Area: 20.31 Å2; (13)Index of Refraction: 1.414; (14)Molar Refractivity: 23.93 cm3; (15)Molar Volume: 95.5 cm3; (16)Polarizability: 9.48×10-24cm3; (17)Surface Tension: 24.7 dyne/cm; (18)Density: 0.89 g/cm3; (19)Flash Point: 103.6 °C; (20)Enthalpy of Vaporization: 44.4 kJ/mol; (21)Boiling Point: 207.7 °C at 760 mmHg; (22)Vapour Pressure: 0.222 mmHg at 25°C.

Preparation: this chemical can be prepared by N-(1-methoxy-ethyl)-acetamide. This reaction temperature is 550 ℃. The yield is about 70%.

 Acetamide, N-ethenyl- can be prepared by N-(1-methoxy-ethyl)-acetamide

When you are using this chemical, please be cautious about it as the following:
The Acetamide, N-ethenyl- irritates to eyes, respiratory system and skin. And this chemical is harmful if swallowed. When use it, wear suitable protective clothing, gloves and eye/face protection. If contact with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1)SMILES: O=C(N\C=C)C
(2)InChI: InChI=1/C4H7NO/c1-3-5-4(2)6/h3H,1H2,2H3,(H,5,6)
(3)InChIKey: RQAKESSLMFZVMC-UHFFFAOYAE
(4)Std. InChI: InChI=1S/C4H7NO/c1-3-5-4(2)6/h3H,1H2,2H3,(H,5,6)
(5)Std. InChIKey: RQAKESSLMFZVMC-UHFFFAOYSA-N

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