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Amphetamine hydrochloride

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Name

Amphetamine hydrochloride

EINECS N/A
CAS No. 2706-50-5 Density g/cm3
PSA 26.02000 LogP 3.07860
Solubility N/A Melting Point 127-129 C
Formula C9H13 N . Cl H Boiling Point 201.5°Cat760mmHg
Molecular Weight 171.67 Flash Point 87.4°C
Transport Information N/A Appearance N/A
Safety Poison by subcutaneous, intravenous, and intraperitoneal routes. When heated to decomposition it emits very toxic fumes of HCl and NOx. See other amphetamine entries. Risk Codes 25
Molecular Structure Molecular Structure of 2706-50-5 (rac AMphetaMine Hydrochloride) Hazard Symbols T
Synonyms

Benzeneethanamine,a-methyl-, hydrochloride (9CI);Benzeneethanamine, a-methyl-, hydrochloride, (?à)-;Phenethylamine, a-methyl-, hydrochloride, (?à)- (8CI);(?à)-Amphetaminehydrochloride;(?à)-a-Methylphenethylaminehydrochloride;1-Phenyl-2-propylamine hydrochloride;Amphetamine hydrochloride;Psychedrine;Psychedrine hydrochloride;dl-Amphetamine hydrochloride;a-Methylbenzeneethanaminehydrochloride;a-Methylphenethylaminehydrochloride;b-Phenylisopropylaminehydrochloride;

Article Data 10

Amphetamine hydrochloride Chemical Properties

IUPAC Name: 1-Phenylpropan-2-amine hydrochloride
Synonyms of Amphetamine hydrochloride (CAS NO.2706-50-5): (+-)-Amphetamine hydrochloride ; (+-)-alpha-Methylphenethylamine hydrochloride ; 1-Phenyl-2-propylamine hydrochloride ; Psychedrine ; Psychedrine hydrochloride ; alpha-Methylbenzeneethanamine hydrochloride ; dl-alpha-Methyl-phenethylamine hydrochloride ; Benzeneethanamine, alpha-methyl-, hydrochloride ; Phenethylamine, alpha-methyl-, hydrochloride, (+-)-
CAS NO: 2706-50-5
Molecular Formula: C9H14ClN
Molecular Weight : 171.6672
Molecular Structure:
H bond acceptors: 1
H bond donors: 2
#Freely Rotating Bonds: 3
Polar Surface Area: 3.24Å2
Flash Point: 87.4 °C
Enthalpy of Vaporization: 43.77 kJ/mol
Boiling Point: 201.5 °C at 760 mmHg
Vapour Pressure: 0.307 mmHg at 25°C

Amphetamine hydrochloride Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LDLo subcutaneous 52mg/kg (52mg/kg) SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE

BEHAVIORAL: TREMOR

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Journal of Pharmacology and Experimental Therapeutics. Vol. 47, Pg. 339, 1933.
mouse LD50 intraperitoneal 40mg/kg (40mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

VASCULAR: BP ELEVATION NOT CHARACTERIZED IN AUTONOMIC SECTION
Journal of Medicinal Chemistry. Vol. 8, Pg. 100, 1965.
mouse LD50 oral 45mg/kg (45mg/kg)   Journal of the American Chemical Society. Vol. 64, Pg. 533, 1942.
rabbit LD50 intravenous 15mg/kg (15mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 79, Pg. 187, 1943.

Amphetamine hydrochloride Safety Profile

Poison by subcutaneous, intravenous, and intraperitoneal routes. When Amphetamine hydrochloride (CAS NO.2706-50-5)is heated to decomposition, it emits very toxic fumes of HCl and NOx. See other amphetamine entries.

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