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Bacampicillin Hydrochloride

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Name

Bacampicillin Hydrochloride

EINECS N/A
CAS No. 37661-08-8 Density N/A
PSA 162.56000 LogP 3.12690
Solubility N/A Melting Point 171-176° (dec)
Formula C21H27 N3 O7 S . Cl H Boiling Point 695.4°C at 760 mmHg
Molecular Weight 501.988 Flash Point 374.3°C
Transport Information N/A Appearance N/A
Safety Poison by intraperitoneal and intravenous routes. Mildly toxic by ingestion and subcutaneous routes. When heated to decomposition it emits very toxic fumes of NOx, SOx, and HCl. Risk Codes N/A
Molecular Structure Molecular Structure of 37661-08-8 (BACAMPICILLIN HYDROCHLORIDE) Hazard Symbols N/A
Synonyms

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[(aminophenylacetyl)amino]-3,3-dimethyl-7-oxo-,1-[(ethoxycarbonyl)oxy]ethyl ester, monohydrochloride, [2S-[2a,5a,6b(S*)]]-; 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[(2R)-aminophenylacetyl]amino]-3,3-dimethyl-7-oxo-,1-[(ethoxycarbonyl)oxy]ethyl ester, monohydrochloride, (2S,5R,6R)- (9CI);Ambacamp; Ambaxin; Bacacil; Bacampicillin-hydrochloride; Bacampicine;Becampicillin hydrochloride; Penglobe; Spectrobid

Article Data 3

Bacampicillin Hydrochloride Chemical Properties

Chemistry informtion about Bacampicillin Hydrochloride(CAS NO.37661-08-8) is:
IUPAC Name: 1-ethoxycarbonyloxyethyl (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate hydrochloride
Synonyms: Ambacamp ; Ambaxin ; Bacacil ; Bapc ; Becampicillin ; O)-3,3-Dimethyl-7-Oxo-,1-((Ethoxycarbonyl)Oxy)Ethylester,Hydrochloride ; Penglobe ; Bacampicillin Hydrochloride
MF: C21H28ClN3O7S
MW: 501.98
EINECS: 253-580-4 
Flash Point: 364.1 °C
Enthalpy of Vaporization: 99.57 kJ/mol
Boiling Point: 678.4 °C at 760 mmHg
Vapour Pressure: 2.92E-18 mmHg at 25°C
Following is the molecular structure of Bacampicillin Hydrochloride(CAS NO.37661-08-8) is:

Bacampicillin Hydrochloride Uses

Bacampicillin Hydrochloride(CAS NO.37661-08-8) is a semisynthetic penicillin that is effective against gram-negative and gram-positive bacteria and is used to treat infections of the intestinal, urinary, and respiratory tracts.

Bacampicillin Hydrochloride Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 176mg/kg (176mg/kg) BEHAVIORAL: EXCITEMENT

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Chemotherapy Vol. 27(Suppl,
mouse LD50 intravenous 184mg/kg (184mg/kg) BEHAVIORAL: EXCITEMENT

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Chemotherapy Vol. 27(Suppl,
mouse LD50 oral 8529mg/kg (8529mg/kg) BEHAVIORAL: EXCITEMENT

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Chemotherapy Vol. 27(Suppl,
mouse LD50 subcutaneous 9475mg/kg (9475mg/kg) BEHAVIORAL: EXCITEMENT

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Chemotherapy Vol. 27(Suppl,
rat LD50 intravenous 176mg/kg (176mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Chemotherapy Vol. 27(Suppl,
rat LD50 oral 10gm/kg (10000mg/kg)   Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 23, Pg. 1735, 1981.
rat LD50 subcutaneous 10gm/kg (10000mg/kg)   Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 23, Pg. 1735, 1981.

Bacampicillin Hydrochloride Safety Profile

Poison by intraperitoneal and intravenous routes. Mildly toxic by ingestion and subcutaneous routes. When heated to decomposition it emits very toxic fumes of NOx, SOx, and HCl.

Bacampicillin Hydrochloride Specification

Bacampicillin Hydrochloride(CAS NO.37661-08-8) is a semisynthetic penicillin with the same activity and uses as ampicillin, but better absorbed on oral administration.

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