Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

Benzopinacole

Related Products

Hot Products

Name

Benzopinacole

EINECS 207-356-8
CAS No. 464-72-2 Density 1.198 g/cm3
PSA 40.46000 LogP 4.85860
Solubility insoluble in water Melting Point 171-173 °C(lit.)
Formula C26H22O2 Boiling Point 506.9 °C at 760 mmHg
Molecular Weight 366.459 Flash Point 224.9 °C
Transport Information N/A Appearance white crystalline powder
Safety 22-24/25-36-26 Risk Codes 20/21/22-36/37/38
Molecular Structure Molecular Structure of 464-72-2 (Benzopinacole) Hazard Symbols IrritantXi; HarmfulXn
Synonyms

Benzopinacol(6CI);1,1,2,2-Tetraphenyl-1,2-ethanediol;Benzophenone pinacol;Benzpinacol;Tetraphenyl-1,2-ethanediol;Tetraphenylethylene glycol;a,a'-Bibenzhydrol;

Article Data 357

Benzopinacole Synthetic route

119-61-9

benzophenone

464-72-2

tetraphenylethane-1,2-diol

Conditions
ConditionsYield
With hydrogen sulfide; phosphorous acid trimethyl ester In diethylene glycol dimethyl ether for 2.75h; Product distribution; Irradiation; variation of solvents, reagents and conditions;100%
With hydrogen sulfide; phosphorous acid trimethyl ester In diethylene glycol dimethyl ether for 2.75h; Irradiation;100%
With iodine; magnesium In diethyl ether; benzene for 0.5h; pinacol coupling; sonication;99%

2C13H10O(1-)*2Na(1+)*4C6H18N3OP

464-72-2

tetraphenylethane-1,2-diol

Conditions
ConditionsYield
With hydrogenchloride100%

(naphthalene)Yb(THF)3

A

ytterbium hydroxide

B

464-72-2

tetraphenylethane-1,2-diol

Conditions
ConditionsYield
With benzophenone; hydrogen cation In tetrahydrofuran addn. of benzophenone in THF to the Yb-compd., hydrolysis; pptn. of Yb(OH)3, benzpinacol detd. in the THF soln. by LSC;A 100%
B 67%
119-61-9

benzophenone

A

91-01-0

1,1-Diphenylmethanol

B

464-72-2

tetraphenylethane-1,2-diol

Conditions
ConditionsYield
With LiCrH4*2LiCl*2THF In tetrahydrofuran at 25℃; for 12h;A 98%
B 2%
With triethylamine; cadmium(II) sulphide In methanol for 6h; Irradiation;A 88%
B 11%
With sodium tetrahydroborate; nickel dichloride In tetrahydrofuran at 20℃; for 0.25h;A 88%
B 4%

2C13H10O(1-)*3C6H18N3OP*Ca(2+)

464-72-2

tetraphenylethane-1,2-diol

Conditions
ConditionsYield
With hydrogenchloride98%
With hydrogenchloride98%
119-61-9

benzophenone

109-73-9

N-butylamine

464-72-2

tetraphenylethane-1,2-diol

Conditions
ConditionsYield
In benzene for 20h; Product distribution; Quantum yield; Irradiation;96%
3808-00-2

α-acetoxy-α-phenylbenzeneacetic acid

A

464-72-2

tetraphenylethane-1,2-diol

B

108-24-7

acetic anhydride

Conditions
ConditionsYield
With triethylamine In acetonitrile Ambient temperature; electrolysis;A 93%
B n/a
With triethylamine In acetonitrile Product distribution; Ambient temperature; electrolysis;A 93%
B n/a
119-61-9

benzophenone

141-97-9

ethyl acetoacetate

464-72-2

tetraphenylethane-1,2-diol

Conditions
ConditionsYield
In benzene for 48h; Irradiation;92%
626-61-9

4-Chloropyridine

119-61-9

benzophenone

A

15031-78-4

2-(4-pyridyl)propan-2-ol

B

1620-30-0

diphenyl(pyridin-4-yl)methanol

C

464-72-2

tetraphenylethane-1,2-diol

Conditions
ConditionsYield
In water; isopropyl alcohol for 24h; Product distribution; Mechanism; Irradiation; conc. H2SO4 added;A 19%
B 6%
C 90%
119-61-9

benzophenone

33966-50-6

SEC-BUTYLAMINE

110-66-7

n-pentanethiol

75-64-9

tert-butylamine

A

38836-40-7

N-2-butylidene-2-aminobutane

B

464-72-2

tetraphenylethane-1,2-diol

Conditions
ConditionsYield
In benzene for 20h; Product distribution; Quantum yield; Irradiation;A 76%
B 90%

Benzopinacole Consensus Reports

Reported in EPA TSCA Inventory.

Benzopinacole Specification

The CAS registry number of 1,1,2,2-Tetraphenylethylene glycol is 464-72-2. Its EINECS registry number is 207-356-8. The IUPAC name is 1,1,2,2-tetraphenylethane-1,2-diol. In addition, the molecular formula is C26H22O2 and the molecular weight is 366.45. What's more, it is a kind of white crystalline powder and belongs to the class of Pharmaceutical Intermediates. It is incompatible with strong oxidizing agents. And it should be stored in a cool and dry place.

Physical properties about this chemical are: (1)ACD/LogP: 5.88; (2)# of Rule of 5 Violations: 1; (3)ACD/LogD (pH 5.5): 5.88; (4)ACD/LogD (pH 7.4): 5.88; (5)ACD/BCF (pH 5.5): 17300.12; (6)ACD/BCF (pH 7.4): 17300.04; (7)ACD/KOC (pH 5.5): 37599.53; (8)ACD/KOC (pH 7.4): 37599.37; (9)#H bond acceptors: 2; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 7; (12)Polar Surface Area: 18.46 Å2; (13)Index of Refraction: 1.648; (14)Molar Refractivity: 111.29 cm3; (15)Molar Volume: 305.8 cm3; (16)Polarizability: 44.12 ×10-24cm3; (17)Surface Tension: 52 dyne/cm; (18)Density: 1.198 g/cm3; (19)Flash Point: 224.9 °C; (20)Enthalpy of Vaporization: 81.8 kJ/mol; (21)Boiling Point: 506.9 °C at 760 mmHg; (22)Vapour Pressure: 4.26E-11 mmHg at 25°C.

Preparation of 1,1,2,2-Tetraphenylethylene glycol: it can be prepared by benzophenone. This reaction will need reagents Mg and chlorotrimethylsilane, catalyst InCl3 and solvent tetrahydrofuran. The reaction time is 24 hours at reaction temperature of 20 °C. The yield is about 49%.

1,1,2,2-Tetraphenylethylene glycol can be prepared by benzophenone.

Uses of 1,1,2,2-Tetraphenylethylene glycol: it can be used as organic synthesis intermediates. In addition, it can be used to get tetraphenylethene. This reaction will need reagent titanium slurry and solvent tetrahydrofuran. The reaction time is 20 hours by heating. The yield is about 85%.

1,1,2,2-Tetraphenylethylene glycol can be used to get tetraphenylethene

When you are using this chemical, please be cautious about it as the following:
This chemical is harmful by inhalation, in contact with skin and if swallowed. It is irritating to eyes, respiratory system and skin. During using it, wear suitable protective clothing and avoid contact with skin and eyes. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. In addition, you should not breathe dust.

You can still convert the following datas into molecular structure:
(1)SMILES: OC(c1ccccc1)(c2ccccc2)C(O)(c3ccccc3)c4ccccc4
(2)InChI: InChI=1/C26H22O2/c27-25(21-13-5-1-6-14-21,22-15-7-2-8-16-22)26(28,23-17-9-3-10-18-23)24-19-11-4-12-20-24/h1-20,27-28H
(3)InChIKey: MFEWNFVBWPABCX-UHFFFAOYAP

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal > 8gm/kg (8000mg/kg)   European Journal of Toxicology and Environmental Hygiene. Vol. 9, Pg. 99, 1976.
mouse LD50 oral > 10gm/kg (10000mg/kg)   European Journal of Toxicology and Environmental Hygiene. Vol. 9, Pg. 99, 1976.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 464-72-2