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Biguanide

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Name

Biguanide

EINECS 200-251-8
CAS No. 56-03-1 Density 1.8 g/cm3
PSA 111.77000 LogP 0.35390
Solubility N/A Melting Point 130°
Formula C2H7 N5 Boiling Point 189.3 °C at 760 mmHg
Molecular Weight 101.111 Flash Point 68.3 °C
Transport Information N/A Appearance solid
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 56-03-1 (Biguanide) Hazard Symbols N/A
Synonyms

Biguanide(6CI,8CI); Biguanides; Diguanide; Guanidine, (aminoiminomethyl)-;Guanylguanidine; Isobiguanide

Article Data 35

Biguanide Synthetic route

50-01-1

guanidine hydrochloride

56-03-1

BIGUANIDE

Conditions
ConditionsYield
at 180 - 185℃;
byproducts: NH3; heating for a few minutes at 180-185°C;
56-03-1

BIGUANIDE

Conditions
ConditionsYield
With sodium methylate at 50℃;
With sodium ethanolate at 50℃;
56-03-1

BIGUANIDE

Conditions
ConditionsYield
With sodium methylate at 50℃;
With sodium ethanolate at 50℃;
With barium dihydroxide
With ethanol; sodium
With sodium hydroxide; ammonia
420-04-2

CYANAMID

113-00-8

guanidine nitrate

56-03-1

BIGUANIDE

17356-08-0

thiourea

A

2114-02-5

amidinothiocarbamide

B

56-03-1

BIGUANIDE

Conditions
ConditionsYield
With phosphorus pentachloride
With thiophosgene
127099-85-8, 780722-26-1

N-Cyanoguanidine

56-03-1

BIGUANIDE

Conditions
ConditionsYield
With ammonium iodide at 173℃;
With ethanol; ammonium chloride at 105℃; in geschlossenem Rohr;
With ammonium chloride at 160℃;
76766-53-5

6,6-Diethyl-1,6-dihydro-1,3,5-triazin-2,4-diamin

A

16439-79-5

2-ureidomelamine

B

56-03-1

BIGUANIDE

Conditions
ConditionsYield
In ethanol; water Heating; Yield given. Title compound not separated from byproducts;

ammonium chloride

127099-85-8, 780722-26-1

N-Cyanoguanidine

56-03-1

BIGUANIDE

127099-85-8, 780722-26-1

N-Cyanoguanidine

ammoniacal copper

ammoniacal copper

56-03-1

BIGUANIDE

Conditions
ConditionsYield
at 100℃; unter Druck;
biguanide nitrate

biguanide nitrate

56-03-1

BIGUANIDE

Conditions
ConditionsYield
With sodium hydroxide; iso-butanol at 50℃;

Biguanide Chemical Properties

Empirical Formula of Biguanide (CAS NO.56-03-1): C2H7N5
Molecular Weight of Biguanide (CAS NO.56-03-1): 101.11 g/mol
EINECS: 200-251-8 
Index of Refraction: 1.733
Density: 1.8 g/cm3
Flash Point: 68.3 °C
Appearance: Solid
Enthalpy of Vaporization: 42.55 kJ/mol
Boiling Point: 189.3 °C at 760 mmHg
Vapour Pressure: 0.573 mmHg at 25 °C
Structure of Biguanide (CAS NO.56-03-1):
              
IUPAC Name: 1-(Diaminomethylidene)guanidine

Biguanide Specification

 Biguanide , its cas register number is 56-03-1. It also can be called 1-(Diaminomethylidene)guanidine ; Hepatitis B hyperimmune globulin ; and HBIG .

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