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1-BROMO-4-(2,2,2-TRIFLUOROETHOXY)BENZENE is a brominated organic compound characterized by the molecular formula C8H6BrF3O. It features a benzene ring with a bromine atom at the 1 position and a trifluoroethoxy group at the 4 position. 1-BROMO-4-(2,2,2-TRIFLUOROETHOXY)BENZENE is utilized in various chemical reactions and organic synthesis processes, and serves as a building block in the production of pharmaceuticals, agrochemicals, and specialty chemicals. Due to its potentially hazardous nature, it is crucial to handle 1-BROMO-4-(2,2,2-TRIFLUOROETHOXY)BENZENE with care to avoid skin and eye irritation, and to prevent ingestion or inhalation.

106854-77-7

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106854-77-7 Usage

Uses

Used in Chemical Reactions and Organic Synthesis:
1-BROMO-4-(2,2,2-TRIFLUOROETHOXY)BENZENE is used as a reactant in various chemical reactions and organic synthesis processes, contributing to the formation of new compounds with diverse applications.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 1-BROMO-4-(2,2,2-TRIFLUOROETHOXY)BENZENE is used as a building block for the development of new drugs. Its unique structure allows for the creation of molecules with specific therapeutic properties.
Used in Agrochemical Production:
1-BROMO-4-(2,2,2-TRIFLUOROETHOXY)BENZENE is also utilized in the agrochemical industry, where it serves as a precursor for the synthesis of various agrochemicals, such as pesticides and herbicides, to enhance crop protection and yield.
Used in Specialty Chemicals Production:
1-BROMO-4-(2,2,2-TRIFLUOROETHOXY)BENZENE is employed in the production of specialty chemicals, which are used in a wide range of applications, including coatings, adhesives, and materials for various industrial processes. Its unique properties make it a valuable component in the development of these specialized products.

Check Digit Verification of cas no

The CAS Registry Mumber 106854-77-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,6,8,5 and 4 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 106854-77:
(8*1)+(7*0)+(6*6)+(5*8)+(4*5)+(3*4)+(2*7)+(1*7)=137
137 % 10 = 7
So 106854-77-7 is a valid CAS Registry Number.

106854-77-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-BROMO-4-(2,2,2-TRIFLUOROETHOXY)BENZENE

1.2 Other means of identification

Product number -
Other names 4-bromophenyl 2,2,2-trifluoroethyl ether

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:106854-77-7 SDS

106854-77-7Relevant articles and documents

HETEROCYCLIC COMPOUNDS AS DELTA-5 DESATURASE INHIBITORS AND METHODS OF USE

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Page/Page column 97, (2021/06/04)

The present disclosure provides compounds useful for the inhibition of Delta-5 Desaturase ("D5D"). The compounds have a general Formula (I) wherein the variables of Formula (I) are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a metabolic or cardiovascular disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula (I).

HETEROCYCLIC COMPOUNDS AS DELTA-5 DESATURASE INHIBITORS AND METHODS OF USE

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Page/Page column 150-151, (2021/06/04)

The present disclosure provides compounds useful for the inhibition of Delta-5 Desaturase ("D5D"). The compounds have a general Formula (I): wherein the variables of Formula (I) are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a metabolic or cardiovascular disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula (I).

Synthesis of trifluoroethyl aromatic compounds

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Paragraph 0049-0053, (2019/05/20)

The invention discloses a three-alkoxides the reference compound (A) synthetic method, is to potassium persulphate (B), trifluoro ethylsulfinate sodium sulfonate (C) and aromatic compound (D) as the raw material, in order to silver nitrate as the catalyst

Fungal lanosterol 14α-demethylase (CYP51) inhibitor Treatment of recurrent vulvovaginal candidiasis Treatment of onychomycosis

Chopra, S.,Dasgupta, A.,Thakare, R.

, p. 855 - 868 (2020/01/21)

Developing a rationally designed, more selective azole antifungal agent that specifically targets the fungal CYP51 over the host CYP51 is a severe unmet need considering a massive shortfall in novel antifungal agents. In this context, oteseconazole (VT-1161) represents a very exciting new development targeting serious fungal infections caused by a wide variety of fungal pathogens including multidrug-resistant Candida responsible for recurrent vulvovaginal candidiasis. This monograph details the various in vitro and in vivo properties exhibited by oteseconazole as well as its current status in clinical trials.

Copper-catalyzed oxidative trifluoroethoxylation of aryl boronic acids with CF3CH2OH

Zhang, Ke,Xu, Xiu-Hua,Qing, Feng-Ling

, p. 24 - 31 (2017/04/14)

A mild and efficient copper-catalyzed oxidative trifluoroethoxylation of aryl and heteroaryl boronic acids with CF3CH2OH has been developed. This protocol tolerates a range of functional groups, allowing access to a variety of aryl and heteroaryl trifluoroethyl ethers.

Method for preparing aryl trifluoroethoxyl ether

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Paragraph 0057; 0058; 0059; 0060;, (2016/10/07)

The invention relates to a method for preparing aryl trifluoroethoxyl ether. The method includes the steps that aryl boron compounds and trifluoroethanol are added to organic solvent, a copper salt catalyst, a ligand and an oxidizing agent are added, a reaction is conducted in a stirring mode for 1-40 hours at the temperature of 0-60 DEG C, filtering is conducted, column chromatography isolation is conducted, and the aryl trifluoroethoxyl ether is obtained. The method is simple in operation, raw materials are easy to obtain, the reaction condition is mild, the substrate universality is wide, the environmental friendliness is achieved, and the method is applicable to industrial application.

HETEROCYCLIC SULFONAMIDE DERIVATIVE AND MEDICINE COMPRISING SAME

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Paragraph 0576; 0577, (2016/12/01)

The present invention provides a compound represented by the formula (I): wherein each symbol is as defined in the DESCRIPTION, or a pharmaceutically acceptable salt thereof. The compound has a superior TRPA1 antagonist activity, and can provide a medicament useful for the prophylaxis or treatment of diseases involving TRPA1 antagonist and TRPA1.

METALLOENZYME INHIBITOR COMPOUNDS

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Page/Page column 43, (2013/07/31)

The present disclosure describes compounds having agricultural fungicidal activity.

METALLOENZYME INHIBITOR COMPOUNDS

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Page/Page column 41, (2013/07/31)

The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.

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