119313-12-1

Basic information

• Product Name: 2-Benzyl-2-(dimethylamino)-4'-morpholinobutyrophenone
• Synonyms: IHT-PI 910;1-(4-Morpholinophenyl)-2-(dimethylamino)-2-benzyl-1-butanone;IC-369;Irgacure 369;N,N-Dimethyl-α-ethyl-α-benzyl-β-oxo-4-(4-morpholinyl)benzeneethanamine;α-(Dimethylamino)-α-benzyl-4'-morpholinobutyrophenone;2-Benzyl-2-(dimethylamino)-4'-morpholinobutyrophenone ,97%;2-(dimethylamino)-1-[4-(4-morpholinyl)phenyl]-2-(phenylmethyl)-1-butanone
• CAS NO: 119313-12-1
• Molecular Formula: C₂₃H₃₀N₂O₂
• Molecular Weight: 366.5
• EINECS: 404-360-3
• Product Categories: chemical additive;Acetophenone;Organic Photoinitiators;Polymerization Initiators
• Mol File: 119313-12-1.mol

Chemical Properties

• Melting Point: 116-119 °C(lit.)
• Boiling Point: 528.8 °C at 760 mmHg
• Flash Point: >230 °F
• Appearance: /
• Density: 1.094 g/cm³
• Vapor Pressure: 0-0.01Pa at 25-95℃
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: 3240 in mg/100g standard fat at 20 ℃
• PKA: 7.04±0.50(Predicted)
• Water Solubility: 5.9mg/L at 20℃
• CAS DataBase Reference: 2-Benzyl-2-(dimethylamino)-4'-morpholinobutyrophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Benzyl-2-(dimethylamino)-4'-morpholinobutyrophenone(119313-12-1)
• EPA Substance Registry System: 2-Benzyl-2-(dimethylamino)-4'-morpholinobutyrophenone(119313-12-1)

Safety Data

• Hazard Codes: N
• Statements: 50/53
• Safety Statements: 60-61
• RIDADR: UN 3077 9/PG 3
• WGK Germany: 2
• RTECS: EL7755000
• HazardClass: 9
• PackingGroup: III
• Hazardous Substances Data: 119313-12-1(Hazardous Substances Data)

Usage

Chemical Properties

Light yellow solid

Uses

Different sources of media describe the Uses of 119313-12-1 differently. You can refer to the following data:
1. DBMP can be used as a dopant to dope silicone elastomer for the formation of 3D biocompatible scaffolds. It can also be used in two photon polymerization for the micro-fabrication of 3D hydrogels for potential biomedical and tissue engineering applications.
2. UV solidify ink and coating

General Description

2-Benzyl-2-(dimethylamino)-4′-morpholinobutyrophenone (DBMP) is a photoinitiator that acts at near UV and visible range. It can be incorporated into the polymeric matrix, which upon UV irradiation forms radicals by radical chain polymerization.

Upstream product

• 110-91-8 morpholine 
• 119312-61-7 2-benzyl-2-(dimethylamino)-1-(4-fluorophenyl)-butan-1-one 
• 584-08-7 potassium carbonate 
• 199109-90-5 2-dimethylamino-1-(4-morpholinylphenyl)-1-butanone 
• 108-90-7 chlorobenzene 
• 4981-63-9 4-n-butanoylchlorobenzene 
• 1011-26-3 2-bromo-1-(4-chlorophenyl)-1-butanone 
• 100-44-7 benzyl chloride 
• 582-83-2 1-(4-fluorophenyl)butan-1-one 
• 462-06-6 fluorobenzene 

Downstream Products

• 141888-26-8 4-morpholinobenzoyl radical 
• 225512-42-5 1-phenyl-2-(dimethylamino)but-2-yl radical 

Relevant articles and documents

A 1 - (4 - morpholino phenyl) -1 - butanone preparation method

The invention relates to a kind of α - amino ethyl ketone photoinitiator intermediate preparation method, in particular to photoinitiator 2 - benzyl - 2 - dimethylamino - 1 - (4 - morpholino phenyl) butanone and 2 - (4 - methyl benzyl) - 2 - dimethylamino - 1 - (4 - morpholino phenyl) butanone intermediate 1 - (4 - morpholino-phenyl) - 1 - butanone. To overcome the shortcomings of the prior art, provides a does not need to add the heavy metal catalyst, does not need high-temperature high-pressure feeding, after treatment is simple, the appearance of the product is good, is suitable for the industrial production of α - amino ethyl ketone photoinitiator preparation method of the midbody.

Synthetic method of 2-benzyl-2-dimethylamino-1-(4-morpholinophenyl) butanone

The invention discloses a synthetic method of 2-benzyl-2-dimethylamino-1-(4-morpholinophenyl) butanone. The synthetic method comprises the following steps: (1) carrying out a Friedel-Crafts reaction on chlorobenzene with n-butyryl chloride under the catalysis of aluminium trichloride to obtain a compound I; (2) carrying out a bromination reaction on the compound I with bromine under the action ofa catalytic oxidizing agent to obtain a compound II; (3) carrying out a substitution reaction on the compound II with dimethylamine to obtain a compound III; (4) carrying out a quaternization reactionon the compound III with benzyl chloride to obtain a compound IV; (5) carrying out a substitution reaction on the compound IV with morpholine under the action of a composite catalyst to obtain a compound V; and (6) carrying out a rearrangement reaction on the compound V under the action of an alkali so as to obtain the 2-benzyl-2-dimethylamino-1-(4-morpholinophenyl) butanone. The synthetic methodprovided by the invention has the advantages of mild technological condition, simple operation, high selectivity and high total yield.

Alpha-amino acetophenone photoinitiator preparation method

The present invention relates to an alpha-amino acetophenone photoinitiator preparation method, particularly to a preparation method of 2-benzyl-2-dimethylamino-1-(4-morpholinophenyl)butanone and 2-(4-methylbenzyl)-2-dimethylamino-1-(4-morpholinophenyl)butanone. According to the present invention, 1-p-fluorophenyl-1-butanone is adopted as the raw material, and only the safe and cheap solvent is used in the whole method to conveniently prepare 2-benzyl-2-dimethylamino-1-(4-morpholinophenyl)butanone and 2-(4-methylbenzyl)-2-dimethylamino-1-(4-morpholinophenyl)butanone; and the method has characteristics of cheap and readily available raw materials, high yield, no requirement of intermediate purification, and continuous reaction without solvent replacement, and is the preparation method with characteristics of low cost, environmental protection and easy operation and suitable for industrialization.

Oxygen-containing titanocenes, and the use thereof

Titanocenes of the formula I STR1 in which R1 are cyclopentadienyl? groups and R2 and R3 are aromatic radicals which are substituted in both ortho-positions by fluorine and, in addition, are substituted by an acyloxy group are suitable as photoinitiators for the photopolymerization of ethylenically unsaturated compounds.

Novel alpha-aminoacetophenones as photoinitiators

Compounds of the formula I, II, III and IIIa STR1 in which Ar1 is an unsubstituted or substituted aromatic radical and at least one of the radicals R1 and R2 is an alkenyl, cycloalkenyl or arylmethyl group, are effective photoinitiators for photopolymerization of unsaturated compounds. They are particularly suitable for photocuring of pigmented systems.

Novel nitrogen-containing titanocenes, and the use thereof

Titanocenes of the formula I STR1 in which R1 are cyclopentadienyl? groups and R2 and R3 are aromatic radicals which are substituted in both ortho-positions by fluorine and, in addition, are substituted by a pyrrylalkyl group, amidoalkyl group or imidoalkyl group, are suitable as photoinitiators for the photopolymerization of ethylenically unsaturated compounds.