125568-73-2

Basic information

• Product Name: Methyl 5-amino-2,4-difluorobenzoate
• Synonyms: Benzoic acid, 5-amino-2,4-difluoro-, methyl ester (9CI);Methyl 5-amino-2,4-difluorobenzoate
• CAS NO: 125568-73-2
• Molecular Formula: C₈H₇F₂NO₂
• Molecular Weight: 187.14
• Product Categories: AMINOACID
• Mol File: 125568-73-2.mol

Chemical Properties

• Boiling Point: 284.049 °C at 760 mmHg
• Flash Point: 125.589 °C
• Appearance: Reddish brown viscous liquid
• Density: 1.355 g/cm³
• Vapor Pressure: 0.003mmHg at 25°C
• Refractive Index: 1.524
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: Methyl 5-amino-2,4-difluorobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 5-amino-2,4-difluorobenzoate(125568-73-2)
• EPA Substance Registry System: Methyl 5-amino-2,4-difluorobenzoate(125568-73-2)

Safety Data

• Hazardous Substances Data: 125568-73-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Methyl 5-amino-2,4-difluorobenzoate is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs with specific therapeutic properties. Its unique structure allows for the creation of molecules with potential medicinal applications.
Used in Agrochemical Industry:
In the agrochemical sector, Methyl 5-amino-2,4-difluorobenzoate is utilized as an intermediate in the production of pesticides, leveraging its chemical structure to enhance the effectiveness of these products in agricultural settings.
Used in Chemical Research:
Methyl 5-amino-2,4-difluorobenzoate is employed as a research chemical in laboratories, where its distinctive attributes are explored for potential applications in organic synthesis and the development of novel chemical compounds.

InChI:InChI=1/C8H7F2NO2/c1-13-8(12)4-2-7(11)6(10)3-5(4)9/h2-3H,11H2,1H3

Upstream product

• 563-79-1 2,3-Dimethyl-2-butene 
• 125568-78-7 methyl 3-azido-4,6-difluorobenzoate 
• 125568-71-0 methyl 2,4-difluoro-5-nitrobenzoate 
• 109-89-7 diethylamine 
• 108-88-3 toluene 
• 1583-58-0 2,4-difluoro-benzoic acid 
• 639858-45-0 5-amino-2,4-difluorobenzoic acid 
• 67-56-1 methanol 

Downstream Products

• 125568-78-7 methyl 3-azido-4,6-difluorobenzoate 
• 125568-84-5 methyl N-benzyl-3-amino-4,6-difluorobenzoate 
• 125568-97-0 2,2,3,3-tetramethyl-1-(2,4-difluoro-5-carbomethoxyphenyl)aziridine 
• 125568-90-3 3,3'-dicarbomethoxy-4,4',6,6'-tetrafluoroazobenzene 
• 1500113-88-1 C₁₇H₁₂F₄N₂O₅ 
• 1500113-89-2 (R)-tert-butyl 4-(3-(2,4-difluoro-5-(methoxycarbonyl)phenyl)-1-(2-hydroxy-1-phenylethyl)ureido)piperidine-1-carboxylate 
• 1500113-90-5 (R)-tert-butyl 4-(3-(2,4-difluoro-5-(methoxycarbonyl)phenyl)-2-oxo-5-phenylimidazolidin-1-yl)piperidine-1-carboxylate 
• 1500113-91-6 (R,Z)-tert-butyl 4-(2-((2,4-difluoro-5-(methoxycarbonyl)phenyl)imino)-4-phenyloxazolidin-3-yl)piperidine-1-carboxylate 
• 1500113-92-7 (R)-5-(3-(1-(tert-butoxycarbonyl)piperidin-4-yl)-2-oxo-4-phenylimidazolidin-1-yl)-2,4-difluorobenzoic acid 

Relevant articles and documents

NON BRAIN PENETRANT A2A INHIBITORS AND METHODS FOR USE IN THE TREATMENT OF CANCERS

The present invention relates to compounds of Formula (I) or pharmaceutically acceptable salts thereof. The invention further relates to the use of the compounds of Formula (I) as A2A inhibitors. The invention also relates to the use of the compounds of F

2-OXO-THIAZOLE DERIVATIVES AS A2A INHIBITORS AND COMPOUNDS FOR USE IN THE TREATMENT OF CANCERS

The present invention relates to compounds of Formula (I) or pharmaceutically acceptable salts or solvates thereof. The invention further relates to the use of the compounds of Formula (I) as A2A inhibitors. The invention also relates to the use of the compounds of Formula (I) for the treatment and/or prevention of cancer. The invention also relates to a process for manufacturing compounds of Formula (I).

CCR5 ANTAGONISTS AS THERAPEUTIC AGENTS

The present invention relates to compounds useful in the treatment of CCR5-related diseases and disorders, for example, useful in the inhibition of HIV replication, the prevention or treatment of an HIV infection, and in the treatment of the resulting acq

CCR5 ANTAGONISTS AS THERAPEUTIC AGENTS

The present invention relates to compounds useful in the treatment of CCR5-related diseases and disorders, for example, useful in the inhibition of HIV replication, the prevention or treatment of an HIV infection, and in the treatment of the resulting acq

CCR5 ANTAGONISTS AS THERAPEUTIC AGENTS

The present invention relates to compounds useful in the treatment of CCR5-related diseases and disorders, for example, useful in the inhibition of HIV replication, the prevention or treatment of an HIV infection, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS).

Descriptive Photochemistry of Polyfluorinated Azide Derivatives of Methyl Benzoate

The photochemistry of several polyfluorinated azide derivatives of methyl benzoate have been studied in a variety of solvents.We have photolyzed methyl 3-azido-6-fluorobenzoate, methyl 3-azido-4-fluorobenzoate, methyl 4-azido-2-fluorobenzoate, methyl 3-azido-2,4-difluorobenzoate, methyl 3-azido-2,6-difluorobenzoate, methyl 3-azido-2,4,6-trifluorobenzoate, and methyl 4-azido-2,3,5,6-tetrafluorobenzoate in toluene, cyclopentane, tetramethylethylene, diethylamine, dimethyl sulfide, dimethyl disulfide, and methanol in an attempt to capture the photogenerated reactive intermediates.Adducts were not formed in cyclopentane, dimethyl disulfide, and methanol solvents.Adducts were formed, however, but in modest yields, in the other solvents.In general the yield of adducts increases with the number of fluorine substituents present, and ortho and para fluorine substituents relative to the azide group are more effective in enhancing the yield of adducts relative to meta fluorine substitution.