126-84-1

Basic information

• Product Name: 2,2-Diethoxypropane
• Synonyms: 2,2-diethoxy-propan;Acetone diethyl ketal;acetonediethylketal;2,2-DIETHOXYPROPANE;ACETONE DIETHYL ACETAL;2,2-DIETHOXYPROPANE, TECH., 85%;Propane, 2,2-diethoxy-;2,2-DIETHOXYPROPANE 95+%
• CAS NO: 126-84-1
• Molecular Formula: C7H16O2
• Molecular Weight: 132.2
• EINECS: 204-808-6
• Product Categories: Acetals/Ketals/Ortho Esters;Building Blocks;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds
• Mol File: 126-84-1.mol

Chemical Properties

• Boiling Point: 116-117 °C(lit.)
• Flash Point: 46 °F
• Appearance: /
• Density: 0.82 g/mL at 25 °C(lit.)
• Vapor Pressure: 24mmHg at 25°C
• Refractive Index: n20/D 1.389(lit.)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2,2-Diethoxypropane(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-Diethoxypropane(126-84-1)
• EPA Substance Registry System: 2,2-Diethoxypropane(126-84-1)

Safety Data

• Hazard Codes: F
• Statements: 11
• Safety Statements: 16-29-33
• RIDADR: UN 3271 3/PG 2
• WGK Germany: 3
• RTECS: AL4900000
• TSCA: Yes
• HazardClass: 3.1
• PackingGroup: II
• Hazardous Substances Data: 126-84-1(Hazardous Substances Data)

Usage

Preparation

To a flask equipped as in Preparation 2-11 and containing 1725 gm (37.5 moles) of ethanol, 18.4 gm (0.058 mole) of mercuric acetate, and 28 ml of 26% boron fluoride etherate (26%) at 30°C is added dropwise over a 15 min period at 45-50°C, 1250 gm (12.5 moles) of isopropenyl acetate. After the reaction 2200 gm of 25% sodium hydroxide is added, the organic layer separated, washed first with 400 ml of 0.01 Ν sodium hydroxide, dried, and distilled to afford 1140 gm (69%), b.p. 110-113 C (760 mm Hg).

Safety Profile

Poison by intraperitoneal route.When heated to decomposition it emits acrid smoke.

InChI:InChI=1/C7H16O2/c1-5-8-7(3,4)9-6-2/h5-6H2,1-4H3

Upstream product

• 108-22-5 Isopropenyl acetate 
• 64-17-5 ethanol 
• 122-51-0 orthoformic acid triethyl ester 
• 67-64-1 acetone 
• 78-10-4 tetraethoxy orthosilicate 
• 16694-46-5 ethyl formimidate hydrochloride 
• 5442-34-2 ethyl 2-phenylacetimidate hydrochloride 
• 77-76-9 2,2-dimethoxy-propane 
• 5447-97-2 2-bromo-2-nitropropane 
• 141-52-6 sodium ethanolate 
• 74-99-7 prop-1-yne 
• 7647-01-0 hydrogenchloride 
• 698-91-9 2-phenoxypropene 
• 926-66-9 2-ethoxyprop-1-ene 

Downstream Products

• 35219-73-9 2,2-bis-allyloxy-propane 
• 87384-19-8 2-ethoxy-2-allyloxy-propane 
• 100-79-8 (R,S)-2,2-dimethyl-1,3-dioxolane-4-methanol 
• 78-79-5 isoprene 
• 504-60-9 penta-1,3-diene 
• 1712-74-9 ethyl cumyl ether 
• 972-46-3 3-ethoxyandrosta-3,5-dien-17-one 
• 72727-64-1 ethyl-(1-cyclohexyl-1-methyl-ethyl)-ether 
• 141-72-0 acetone-dibutylacetal 
• 90724-77-9 2-ethoxy-2-butoxy-propane 
• 926-66-9 2-ethoxyprop-1-ene 
• 16647-04-4 6-methylhepta-3,5-dien-2-one 
• 10076-57-0 2,2-bis-pentyloxy-propane 
• 96976-79-3 2,2-Dilauryloxy-propan 

Relevant articles and documents

Solvent-free synthesis of unsaturated ketones by the Saucy-Marbet reaction using simple ammonium ionic liquid as a catalyst

Simple ammonium ionic liquids are efficient catalysts in promoting Saucy-Marbet reactions of unsaturated alcohols with unsaturated ethers to afford the corresponding unsaturated ketones, eliminating the need for volatile organic solvents. The effect of th

Influence of Solvent and Counterion in the Reactions of Alkoxide Ions with the 2-Nitropropan-2-yl Radical

Photostimulated free radical chain reactions between alkoxide ions derived from primary alcohols and XCMe2NO2 (X= Cl, Br, NO2, PhSO2, N3, or p-ClC6H4S) occur to produce Me2C(OR)2 by reaction involving the trapping of Me2C(NO2). by RO-, the decomposition of ROCMe2NO2.- to ROCMe2., and the oxidation of ROCMe2. to Me2C=OR+ by XCMe2NO2.

Method for synthesizing 2,2-dialkoxyl propane

The invention provides a method for synthesizing 2,2-dialkoxyl propane and co-produced 2-alkoxyl propane. Acetone, alcohol and tetraethyl orthosilicate serve as the raw materials and can be highly selectively synthesized into 2,2-dialkoxyl propane under certain conditions or react to generate 2,2-dialkoxyl propane and 2-alkoxyl propane at the same time. The method has the advantages that the synthesis process is simple, safe and environmentally friendly, product separation is easy, energy consumption is low, and product purity and yield are high.

Synthesis of biodiesel without formation of free glycerol

A new approach to the synthesis of biodiesel has been developed on the basis of alcoholysis of a triglyceride in combination with acetalization of glycerol with lower carbonyl compounds or acetals derived therefrom. A model synthesis of biodiesel not involving free glycerol has been accomplished using rapeseed oil and acid catalysts, as well as without a catalyst under generation of ethanol supercritical fluid; in the latter case, monoalkyl glycerol ethers are formed in addition to the expected cyclic ketals.

Alkylation and acetal formation using supercritical alcohol without catalyst

The aromatic ring alkylation of phenols, N-alkylation of aniline, O-alkylation of phenols and acetal formation from acetaldehyde or acetone were examined using supercritical (SC) alcohol without any catalyst. Highly selective syntheses of monoalkylated compounds were achieved for the aromatic ring alkylation and N-alkylation. The O-alkylation proceeded more preferentially than the aromatic ring alkylation for phenols which have a deactivating group. The acetal formation went on in more than 96% selectivity.

Manufacture of dialkyl-ketals

Dialkyl-ketals are manufactured by reacting ketones with alkanols in the presence of an acid condensing agent and of an at least equivalent amount, based on the ketone, of anhydrous calcium sulfate.