143139-14-4

Basic information

• Product Name: TRIFLUORO-METHANESULFONIC ACID 3,4-DIHYDRO-NAPHTHALEN-2-YL ESTER
• Synonyms: TRIFLUORO-METHANESULFONIC ACID 3,4-DIHYDRO-NAPHTHALEN-2-YL ESTER;3,4-Dihydronaphthalen-2-yl trifluoromethanesulfonate
• CAS NO: 143139-14-4
• Molecular Formula: C₁₁H₉F₃O₃S
• Molecular Weight: 278.25
• Mol File: 143139-14-4.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: TRIFLUORO-METHANESULFONIC ACID 3,4-DIHYDRO-NAPHTHALEN-2-YL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: TRIFLUORO-METHANESULFONIC ACID 3,4-DIHYDRO-NAPHTHALEN-2-YL ESTER(143139-14-4)
• EPA Substance Registry System: TRIFLUORO-METHANESULFONIC ACID 3,4-DIHYDRO-NAPHTHALEN-2-YL ESTER(143139-14-4)

Safety Data

• Hazardous Substances Data: 143139-14-4(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis Industry:
TRIFLUORO-METHANESULFONIC ACID 3,4-DIHYDRO-NAPHTHALEN-2-YL ESTER is used as a catalyst in organic synthesis reactions for its enhanced reactivity and stability. It facilitates various chemical transformations, improving the efficiency and selectivity of the reactions.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, TRIFLUORO-METHANESULFONIC ACID 3,4-DIHYDRO-NAPHTHALEN-2-YL ESTER is used as a catalyst for the synthesis of various pharmaceutical compounds. Its reactivity and stability contribute to the production of high-quality and efficient drugs.
Used in Agrochemical Industry:
TRIFLUORO-METHANESULFONIC ACID 3,4-DIHYDRO-NAPHTHALEN-2-YL ESTER is employed as a catalyst in the synthesis of agrochemicals, such as pesticides and herbicides. Its ability to enhance the reactivity and stability of chemical reactions aids in the development of effective and environmentally friendly agrochemicals.
Used in Material Science:
In the field of material science, TRIFLUORO-METHANESULFONIC ACID 3,4-DIHYDRO-NAPHTHALEN-2-YL ESTER is utilized as a catalyst for the synthesis of advanced materials, including polymers and composites. Its reactivity and stability contribute to the development of materials with improved properties and performance.

Upstream product

• 358-23-6 trifluoromethylsulfonic anhydride 
• 530-93-8 1,2,3,4-tetrahydronaphthalen-2-one 
• 456-64-4 phenyl trifluoromethanesulfonamide 
• 140-29-4 phenylacetonitrile 
• 555-21-5 4-Nitrophenylacetonitrile 
• 100-47-0 benzonitrile 
• 104-85-8 para-methylbenzonitrile 
• 2947-61-7 (4-methylphenyl)acetonitrile 
• 3218-49-3 3,4-dichloro-benzeneacetonitrile 
• 75-05-8 acetonitrile 
• 22364-68-7 2-tolylmethylnitrile 
• 140-53-4 p-chlorobenzyl cyanide 
• 37595-74-7 N,N-phenylbistrifluoromethane-sulfonimide 
• 38553-85-4 β-tetralone 

Downstream Products

• 20669-52-7 3-phenyl-1,2-dihydronaphthalene 
• 92013-27-9 3-bromo-1,2-dihydroxynaphthalene 
• 126745-32-2 1,2-dihydro-3-(phenylthio)naphthalene 
• 1361131-99-8 C₁₇H₁₆O 
• 1361132-00-4 C₁₇H₁₈O 
• 1361132-01-5 C₁₇H₁₆O 
• 1361132-12-8 1,3-dimethyl-5-(2-(1,2,3,4-tetrahydronaphthalen-2-yl)benzylidene)pyrimidine-2,4,6(1H,3H,5H)-trione 
• 1402012-54-7 1,1'-biphenyl-4-yl 3,4-dihydronaphthalene-2-carboxylate 
• 1402012-56-9 4-chlorophenyl 3,4-dihydronaphthalene-2-carboxylate 
• 1402012-57-0 4-trifluoromethylphenyl 3,4-dihydronaphthalene-2-carboxylate 
• 1402012-58-1 2,4,6-trichlorophenyl 3,4-dihydronaphthalene-2-carboxylate 
• 1402012-60-5 2,6-difluorophenyl 3,4-dihydronaphthalene-2-carboxylate 
• 1397263-67-0 phenyl 3,4-dihydronaphthalene-2-carboxylate 
• 1449115-43-8 4-(3,4-dihydronaphthalen-2-yl)-1-tosyl-1H-1,2,3-triazole 

Relevant articles and documents

COMPOUNDS AS GLP-1R AGONISTS

The present application provides compounds that may be used as a glucagon-like peptide-1 receptors (GLP-1R) agonist, or stereoisomers, tautomers, or pharmaceutically acceptable salts of any of the foregoing. Also provided are pharmaceutical compositions containing such compounds, or stereoisomers, tautomers, or pharmaceutically acceptable salts of any of the foregoing. Methods of prepare these compounds and compositions and method of using them to treat or present a disease or a condition mediated by GLP-1R.

Iron-Catalyzed Tertiary Alkylation of Terminal Alkynes with 1,3-Diesters via a Functionalized Alkyl Radical

Direct oxidative C(sp)?H/C(sp3)?H cross-coupling offers an ideal and environmentally benign protocol for C(sp)?C(sp3) bond formations. As such, reactivity and site-selectivity with respect to C(sp3)?H bond cleavage have remained a persistent challenge. Herein is reported a simple method for iron-catalyzed/silver-mediated tertiary alkylation of terminal alkynes with readily available and versatile 1,3-dicarbonyl compounds. The reaction is suitable for an array of substrates and proceeds in a highly selective manner even employing alkanes containing other tertiary, benzylic, and C(sp3)?H bonds alpha to heteroatoms. Elaboration of the products enables the synthesis of a series of versatile building blocks. Control experiments implicate the in situ generation of a tertiary carbon-centered radical species.

Alkenylation and Arylation of Peptides via Ni-Catalyzed Reductive Coupling of α- C-Tosyl Peptides with Csp2Triflates/Halides

A Ni-catalyzed reductive cross-coupling between α-C-tosyl peptides and Csp2 triflates/halides has been developed. This protocol enables the formation of various unnatural di- and tripeptides containing vinyl and aryl side chains, and it expands the applications of Ni-catalyzed reductive cross-coupling in late-stage diversification of peptides.

GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE

Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with a defect in glyoxylate metabolism, for example a disease or disorder associated with the enzyme glycolate oxidase (GO) or alterations in oxalate metabolism. Such diseases or disorders include, for example, disorders of glyoxylate metabolism, including primary hyperoxaluria, that are associated with production of excessive amounts of oxalate.

A Stepwise Annulation for the Transformation of Cyclic Ketones to Fused 6 and 7-Membered Cyclic Enimines and Enones

The efficient construction of functionalized polycyclic structures is an important objective in organic synthesis. Herein, we disclose a three-step “[2 + n]” annulation method for the transformation of cyclic ketones to fused enimines and enones. The method relies on the Suzuki coupling reaction and the amide reductive alkenylation reaction. A series of fused bicyclic (6/6, 6/7, 8/7) and tricyclic (6/6/6; 6/6/7, 6/5/7) ring systems bearing an α,β-enimine or an α,β-enone functionality have been synthetized in good overall yields.

Cyclic Alkenylsulfonyl Fluorides: Palladium-Catalyzed Synthesis and Functionalization of Compact Multifunctional Reagents

A series of low-molecular-weight, compact, and multifunctional cyclic alkenylsulfonyl fluorides were efficiently prepared from the corresponding alkenyl triflates. Palladium-catalyzed sulfur dioxide insertion using the surrogate reagent DABSO effects sulfinate formation, before trapping with an F electrophile delivers the sulfonyl fluorides. A broad range of functional groups are tolerated, and a correspondingly large collection of derivatization reactions are possible on the products, including substitution at sulfur, conjugate addition, and N-functionalization. Together, these attributes suggest that this method could find new applications in chemical biology.

GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE

Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with the enzyme glycolate oxidase (GO). Such diseases or disorders include, for example, disorders of glyoxylate metabolism, including primary hyperoxaluria, that are associated with production of excessive amounts of oxalate.

One-Pot Relay Gold(I) and Br?nsted Acid Catalysis: Cyclopenta[b]annulation of Indoles via Hydroamination/Nazarov-Type Cyclization Cascade of Enynols

An expedient relay gold(I) and Br?nsted acid catalyzed hydroamination/Nazarov cyclization of 1-(2-aminophenyl)pent-4-en-2-ynols for the synthesis of various polyfunctionalized cyclopenta[b]indoles is described. The synthetic utility of this method has bee

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