150529-73-0

Basic information

• Product Name: (3-BROMOPHENYL)ACETIC ACID METHYL ESTER
• Synonyms: METHYL 2-(3-BROMOPHENYL)ACETATE;(3-BROMOPHENYL)ACETIC ACID METHYL ESTER;Methyl 3-bromophenylacetate 98%;Methyl 3-bromophenylacetate;3-Bromophenylacetic acid methyl ester, Methyl 2-(3-bromophenyl)ethanoate;Methyl3-bromophenylacetate98%
• CAS NO: 150529-73-0
• Molecular Formula: C₉H₉BrO₂
• Molecular Weight: 229.07
• Product Categories: blocks;Bromides;Carboxes;pharmacetical
• Mol File: 150529-73-0.mol

Chemical Properties

• Boiling Point: 268.639 °C at 760 mmHg
• Flash Point: 116.269 °C
• Appearance: /
• Density: 1.446 g/cm³
• Vapor Pressure: 0.008mmHg at 25°C
• Refractive Index: 1.5440 to 1.5480
• Storage Temp.: Keep Cold
• CAS DataBase Reference: (3-BROMOPHENYL)ACETIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (3-BROMOPHENYL)ACETIC ACID METHYL ESTER(150529-73-0)
• EPA Substance Registry System: (3-BROMOPHENYL)ACETIC ACID METHYL ESTER(150529-73-0)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 150529-73-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
(3-BROMOPHENYL)ACETIC ACID METHYL ESTER is used as a reagent for the synthesis of the methyl ester derivative of (R)-Flurbiprofen (F598730). (3-BROMOPHENYL)ACETIC ACID METHYL ESTER is a nonsteroidal anti-inflammatory drug (NSAID) that is known for its anti-inflammatory, analgesic, and antipyretic properties. It is commonly used to treat various conditions such as arthritis, ankylosing spondylitis, and soft tissue rheumatism.
Additionally, (R)-Flurbiprofen has potential applications in the treatment of patients with Alzheimer's Disease. The compound has been shown to modulate the activity of the enzyme cyclooxygenase-1 (COX-1), which is involved in the production of amyloid-beta peptides, a hallmark of Alzheimer's Disease. By inhibiting COX-1, (R)-Flurbiprofen may help reduce the formation of amyloid-beta peptides and slow down the progression of the disease.

InChI:InChI=1/C9H9BrO2/c1-12-9(11)6-7-3-2-4-8(10)5-7/h2-5H,6H2,1H3

Upstream product

• 67-56-1 methanol 
• 35065-86-2 3-bromophenyl acetate 
• 1878-67-7 3-Bromophenylacetic acid 
• 74-88-4 methyl iodide 
• 186581-53-3 diazomethane 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 124-41-4 sodium methylate 
• 1360789-08-7 2-(3-bromophenyl)-1-(2,2,6,6-tetramethylpiperidin-1-yl)ethanone 
• 18698-97-0 ortho-bromophenylacetic acid 
• 75-36-5 acetyl chloride 

Downstream Products

• 1026707-56-1 (3-{3-[3-(Tetrahydro-pyran-2-yloxy)-propyl]-benzyl}-phenyl)-acetic acid methyl ester 
• 859232-71-6 4-bromo-2-(methoxycarbonylmethyl)benzenesulfonamide 
• 109347-40-2 2-(3-bromophenyl)acetaldehyde 
• 944924-92-9 4-(3-bromo-phenyl)-tetrahydro-pyran-4-carboxylic acid methyl ester 
• 852470-84-9 methyl 2-(3-bromophenyl)acrylate 
• 89723-25-1 (3-ethyl-phenyl)-acetic acid 
• 494222-23-0 4-[(2-{(2R)-2-[(1E,3S)-3-hydroxy-4-(3-n-propylphenyl)but-1-enyl]-5-oxopyrrolidin-1-yl}ethyl)sulfanyl]butanoic acid 
• 1365392-05-7 C₂₄H₃₅NO₄S 
• 494221-85-1 7-{(2R)-2-[(1E,3S)-3-hydroxy-4-(3-propylphenyl)but-1-enyl]-5-oxopyrrolidin-1-yl}heptanoic acid 
• 1365391-83-8 ethyl 7-{(2R)-2-[(1E,3S)-3-hydroxy-4-(3-n-propylphenyl)-1-buten-1-yl]-5-oxo-1-pyrrolidinyl}heptanoate 
• 1357177-82-2 dimethyl [3-(3-n-propylphenyl)-2-oxopropane]phosphonate 
• 18698-76-5 C₁₁H₁₄O₂ 
• 494221-81-7 7-{(2R)-2-[(1E,3S)-3-hydroxy-4-(3-ethylphenyl)but-1-enyl]-5-oxopyrrolidin-1-yl}heptanoic acid 
• 1365391-79-2 ethyl 7-{(2R)-2-[(1E,3S)-3-hydroxy-4-(3-ethylphenyl)-1-buten-1-yl]-5-oxo-1-pyrrolidinyl}heptanoate 

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