166398-41-0Relevant articles and documents
A palladium/norbornene cooperative catalysis to access N-containing bridged scaffolds
Gao, Qianwen,Liu, Ze-Shui,Hua, Yu,Li, Lisha,Cheng, Hong-Gang,Cong, Hengjiang,Zhou, Qianghui
supporting information, p. 8816 - 8819 (2019/07/31)
A palladium/norbornene cooperative catalysis promoted annulation involving an ortho-C-H amination and intramolecular Heck cascade between aryl iodides and functionalized amination reagents is reported, thereby providing a highly convergent access to the u
CRYSTALLINE FORMS
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Page/Page column 20, (2017/04/05)
The invention relates to a crystalline form of (S)-2-(8-((5-chloropyrimidin-2-yl)(methyl)amino)- 2-fluoro-6,7,8,9-tetrahydro-5H-pyrido[3,2-b]indol-5-yl)acetic acid, processes for the preparation thereof, pharmaceutical compositions comprising said crystal
AZAINDOLE ACETIC ACID DERIVATIVES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR MODULATORS
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Page/Page column 15, (2015/11/10)
The present invention relates to azaindole acetic acid derivatives of formula (I), (I) wherein R1 and R2 are as described in the description and their use as prostaglandin receptor modulators, most particularly as prostaglandin D2 receptor modulators, in the treatment of various prostaglandin-mediated diseases and disorders, to pharmaceutical compositions containing these compounds and to processes for their preparation.
AZAINDOLE ACETIC ACID DERIVATIVES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR MODULATORS
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Page/Page column 19; 20, (2016/01/26)
The present invention relates to azaindole acetic acid derivatives of formula (I), wherein R1 and R2 are as described in the description, and their use as prostaglandin receptor modulators, most particularly as prostaglandin D2
N,N-Dimethyl-[9-(arylsulfonyl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl]amines as novel, potent and selective 5-HT6 receptor antagonists
Nirogi, Ramakrishna V. S.,Konda, Jagadishu Babu,Kambhampati, Ramasastry,Shinde, Anil,Bandyala, Thrinath Reddy,Gudla, Parandhama,Kandukuri, Kiran Kumar,Jayarajan, Pradeep,Kandikere, Vishwottam,Dubey, P. K.
supporting information, p. 6980 - 6985,6 (2020/09/02)
The design, synthesis and SAR of novel tetrahydrocarbazole derivatives having 5-HT6 receptor antagonist activity is presented. The racemic compound 15e was found to possess desirable pharmacokinetic properties, adequate brain penetration and activity in animal models of cognition.
Substituted Benzamide Compounds
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Page/Page column 139, (2012/04/04)
Substituted benzamide compounds corresponding to formula (I) in which R5, R6, R7, R8, a, b, c, d, t, D and X have defined meanings, a process for their preparation, pharmaceutical compositions comprising such compounds, and a method of using such compounds to treat pain and other conditions mediated at least in part via the bradykinin 1 receptor.
Biotin tethered homotryptamine derivatives: High affinity probes of the human serotonin transporter (hSERT)
Tomlinson, Ian D.,Iwamoto, Hideki,Blakely, Randy D.,Rosenthal, Sandra J.
experimental part, p. 1678 - 1682 (2011/05/05)
Quantum dot conjugates of compounds capable of inhibiting the serotonin transporter (SERT) could form the basis of fluorescent probes for live cell imaging of membrane bound SERT. Additionally, quantum dot-SERT antagonist conjugates may be amenable to flu
CYCLOALKANE[B]AZAINDOLE ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS
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Page/Page column 10, (2010/05/13)
Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions that include the compounds described herein, and methods of using such antagonists of PGD2 receptors, alone or in c
MEDICAMENTS
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Page/Page column 63, (2009/06/27)
A compound of formula (I) is described: wherein R1 and R2 are as defined in the text and wherein the compounds are intended for use in treating medical conditions characterized by an imbalance in dopamine receptor activity.
Novel 2,4-Dianilinopyrimidine Derivatives, the Preparation Thereof, Their Use as Medicaments, Pharmaceutical Compositions and, in Particular, as IKK Inhibitors
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Page/Page column 56, (2008/12/04)
The disclosure relates to compounds of formula (I): wherein R1-R5, A and Y are as defined in the disclosure, to compositions comprising said compounds, and to processes for making and methods of using the same.