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2-Dimethylaminobutan-1-ol, also known as 2-Dimethylamino-1-butanol, is a chemical compound with the molecular formula C6H15NO. It is a tertiary amine and primary alcohol that is commonly used as a chemical intermediate in the production of pharmaceuticals, cosmetics, and dyes. It is known for its ability to act as a pH-regulator and emulsifying agent in various industrial processes. Additionally, 2-Dimethylaminobutan-1-ol exhibits mild amine-like odors and is considered to be a mild skin and eye irritant, with potential for respiratory irritation if inhaled in high concentrations.

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  • 17199-17-6 Structure
  • Basic information

    1. Product Name: 2-dimethylaminobutan-1-ol
    2. Synonyms: 2-dimethylaminobutan-1-ol;(R)-2-Dimethylamino-butan-1-ol;2-(dimethylamino)-1-butanol(SALTDATA: FREE)
    3. CAS NO:17199-17-6
    4. Molecular Formula: C6H15NO
    5. Molecular Weight: 117.19
    6. EINECS: N/A
    7. Product Categories: Chiral Alcohols
    8. Mol File: 17199-17-6.mol
  • Chemical Properties

    1. Melting Point: 178-180 °C
    2. Boiling Point: 157.8 °C at 760 mmHg
    3. Flash Point: 42.9 °C
    4. Appearance: /
    5. Density: 0.883 g/cm3
    6. Vapor Pressure: 0.965mmHg at 25°C
    7. Refractive Index: 1.441
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. PKA: 14.69±0.10(Predicted)
    11. CAS DataBase Reference: 2-dimethylaminobutan-1-ol(CAS DataBase Reference)
    12. NIST Chemistry Reference: 2-dimethylaminobutan-1-ol(17199-17-6)
    13. EPA Substance Registry System: 2-dimethylaminobutan-1-ol(17199-17-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 17199-17-6(Hazardous Substances Data)

17199-17-6 Usage

Uses

Used in Pharmaceutical Industry:
2-Dimethylaminobutan-1-ol is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its ability to act as a pH-regulator and emulsifying agent makes it suitable for use in the development of medications and other healthcare products.
Used in Cosmetics Industry:
In the cosmetics industry, 2-Dimethylaminobutan-1-ol is used as a chemical intermediate for the production of various cosmetic products. Its properties as a pH-regulator and emulsifying agent contribute to the formulation and stability of these products.
Used in Dyes Industry:
2-Dimethylaminobutan-1-ol is used as a chemical intermediate in the production of dyes. Its versatility in chemical reactions allows for the creation of a wide range of dyes for various applications.
Used as a pH-Regulator:
2-Dimethylaminobutan-1-ol is used as a pH-regulator in various industrial processes. Its ability to maintain a stable pH level is essential for the proper functioning and effectiveness of certain products and processes.
Used as an Emulsifying Agent:
In addition to its use as a pH-regulator, 2-Dimethylaminobutan-1-ol also serves as an emulsifying agent. This property allows it to help mix and stabilize different substances, improving the overall performance and quality of various products.
It is important to handle and store 2-Dimethylaminobutan-1-ol with proper safety precautions to minimize potential health and environmental risks due to its mild skin and eye irritant properties and potential for respiratory irritation if inhaled in high concentrations.

Check Digit Verification of cas no

The CAS Registry Mumber 17199-17-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,1,9 and 9 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 17199-17:
(7*1)+(6*7)+(5*1)+(4*9)+(3*9)+(2*1)+(1*7)=126
126 % 10 = 6
So 17199-17-6 is a valid CAS Registry Number.
InChI:InChI=1/C6H15NO/c1-4-6(5-8)7(2)3/h6,8H,4-5H2,1-3H3

17199-17-6Relevant articles and documents

Hemilabile Ligands in Organolithium Chemistry: Substituent Effects on Lithium Ion Chelation

Ramirez, Antonio,Lobkovsky, Emil,Collum, David B.

, p. 15376 - 15387 (2003)

The lithium diisopropylamide-mediated 1,2-elimination of 1-bromocyclooctene to provide cyclooctyne is investigated using approximately 50 potentially hemilabile polyethers and amino ethers. Rate laws for selected ligands reveal chelated monomer-based pathways. The dependence of the rates on ligand structure shows that anticipated rate accelerations based on the gem-dimethyl effect are nonexistent and that substituents generally retard the reaction. With the aid of semiempirical and DFT computational studies, the factors influencing chelation are discussed. It seems that severe buttressing within chelates of the substitutionally rich ligands precludes a net stabilization of the chelates relative to nonchelated (η 1-solvated) forms. One ligand-MeOCH2CH2NMe 2-appears to promote elimination uniquely by a higher-coordinate monomer-based pathway.

Stereospecific Palladium-Promoted Oxyamination of Alkenes

Baeckvall, Jan E.,Bjoerkman, Eva E.

, p. 2893 - 2898 (2007/10/02)

A method for direct oxyamination of olefins to vicinal amino alcohol derivatives is described. The reaction proceeds via an aminopalladation-oxidation sequence.Terminal olefins give good yields (60-80percent) whereas internal olefins give lower yields (20-60percent).The oxyamination reaction is stereospecific as shown by reaction of (Z)- and (E)-2-butene and (E)-1-deuterio-1-decene and proceeds by overall cis stereochemistry.The stereochemical outcome is a result of a trans aminopalladation followed by an oxidative cleavage of the palladium carbon bond with inversion of configuration at carbon.Oxidation of the organopalladium ? complex to give an oxidized palladium intermediate, which could be a Pd(IV) intermediate, followed by SN2-type nucleophilic displacement of palladium is the most likely mechanism for the oxidative cleavage reaction.

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