17962-38-8 Usage
Uses
Used in Organic Synthesis:
DIETHYL(TRIMETHYLSILYLMETHYL)MALONATE is used as a reagent for the synthesis of various organic compounds due to its trimethylsilyl-protected methyl group, which facilitates the formation of carbon-carbon bonds and the creation of complex molecular structures.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, DIETHYL(TRIMETHYLSILYLMETHYL)MALONATE is utilized as a building block for the synthesis of complex molecules with potential therapeutic applications, contributing to the development of new drugs.
Used in Agricultural Industry:
Similarly, in agriculture, DIETHYL(TRIMETHYLSILYLMETHYL)MALONATE is employed in the synthesis of molecules with pesticidal or herbicidal properties, thereby aiding in the production of more effective crop protection agents.
Used as a Cross-Coupling Reagent:
DIETHYL(TRIMETHYLSILYLMETHYL)MALONATE is also used as a cross-coupling reagent in organic reactions, particularly for the formation of carbon-carbon bonds, which is crucial in assembling larger and more complex organic molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 17962-38-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,9,6 and 2 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 17962-38:
(7*1)+(6*7)+(5*9)+(4*6)+(3*2)+(2*3)+(1*8)=138
138 % 10 = 8
So 17962-38-8 is a valid CAS Registry Number.
InChI:InChI=1/C7H10N2/c1-2-3-7-6-8-4-5-9-7/h4-6H,2-3H2,1H3
17962-38-8Relevant articles and documents
Synthesis of rac-2′-(trimethylsilyl)isovaline: A novel silicon-containing α,α-dialkylated α-amino acid
Falgner, Steffen,Buchner, Ginka,Tacke, Reinhold
, p. 2614 - 2617 (2010)
An efficient, convenient, and reliable multi-step synthesis of rac-2′-(trimethylsilyl)isovaline (rac-3) that uses inexpensive reagents in all steps has been developed, starting from diethyl malonate (overall yield 28%). Compound rac-3 is the first α-ethyl
β-silyl effects on the stabilities of carbanions and carbon-centered radicals derived from ethyl thionacetates, diethyl malonates, and ethyl acetoacetates
Zhang, Shizhong,Bordwell, Frederick G.
, p. 51 - 54 (2007/10/03)
The effects of an α-Me3SiCH2 group on the equilibrium acidities in DMSO of the acidic C-H bonds in esters, including ethyl thionacetate, diethyl malonate, and ethyl acetoacetate, were found to differ from that of an α-MeCH2/sub
2-ALKOXYCARBONYLALLYLTRIMETHYLSILANES AS NEW REAGENTS OF 2-ALKOXYCARBONYLALLYLATION OF ELECTROPHILES
Hosomi, Akira,Hashimoto, Hidehiko,Sakurai, Hideki
, p. 951 - 954 (2007/10/02)
2-Alkoxycarbonylallylsilanes are useful for 2-alkoxycarbonylallylation of acetals and carbonyl compounds with an aid of a Lewis acid; the products can be readily converted to α-methylene-γ-butyrolactones.
