74976-84-4

Basic information

• Product Name: ETHYL 2-(TRIMETHYLSILYLMETHYL)ACRYLATE
• Synonyms: 2-(TRIMETHYLSILYLMETHYL)ACRYLIC ACID ETHYL ESTER;ETHYL 2-(TRIMETHYLSILYLMETHYL)ACRYLATE;ETHYL 2-(TRIMETHYLSILYLMETHYL)PROPENOATE;2-(Trimethylsilylmethyl)acrylic acid ethyl ester, Ethyl 2-(trimethylsilylmethyl)propenoate;2-Ethoxycarbonylallyltrimethylsilane
• CAS NO: 74976-84-4
• Molecular Formula: C₉H₁₈O₂Si
• Molecular Weight: 186.32
• Mol File: 74976-84-4.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 70-72 °C10 mm Hg(lit.)
• Flash Point: 140 °F
• Appearance: /
• Density: 0.897 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.596mmHg at 25°C
• Refractive Index: n20/D 1.438(lit.)
• Storage Temp.: 2-8°C
• BRN: 4658894
• CAS DataBase Reference: ETHYL 2-(TRIMETHYLSILYLMETHYL)ACRYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 2-(TRIMETHYLSILYLMETHYL)ACRYLATE(74976-84-4)
• EPA Substance Registry System: ETHYL 2-(TRIMETHYLSILYLMETHYL)ACRYLATE(74976-84-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• RIDADR: 1993
• WGK Germany: 3
• F: 10-21
• HazardClass: 3.2
• PackingGroup: III
• Hazardous Substances Data: 74976-84-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H18O2Si/c1-6-11-9(10)8(2)7-12(3,4)5/h2,6-7H2,1,3-5H3

Upstream product

• 50-00-0 formaldehyd 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 2344-80-1 Chloromethyltrimethylsilane 
• 13170-43-9 (trimethylsilyl)methylmagnesium chloride 
• 4755-77-5 Ethyl oxalyl chloride 
• 105-53-3 diethyl malonate 
• 17962-38-8 diethyl<(trimethylsilyl)methyl>malonate 
• 84681-39-0 ethyl 2-(hydroxymethyl)-3-(trimethylsilyl)propionate 
• 110481-61-3 3-trimethylsilyl-2-diethylphosphonopropionic acid ethyl ester 
• 75-77-4 chloro-trimethyl-silane 
• 17435-72-2 ethyl 2-bromomethyl-2-propenoate 
• 84681-40-3 ethyl 2-(((methylsulfonyl)oxy)methyl)-3-(trimethylsilyl)propionate 
• 100548-24-1 Ethyl 2-hydroxy-2,2-bis-acetate 
• 18027-74-2 bromomethyl-trimethylsilanylmethyl-malonic acid diethyl ester 

Downstream Products

• 1220349-95-0 ethyl 4-(((benzyloxy)carbonyl)amino)-2-methyleneoct-7-enoate 
• 1266145-53-2 C₁₂H₁₈O₃ 
• 1266145-64-5 C₁₂H₁₈O₃ 
• 287935-00-6 Phenylselanyl-acetic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 
• 75366-42-6 4-Methoxy-2-methylene-4-phenyl-butyric acid ethyl ester 

Relevant articles and documents

A Novel Approach to Complex Terpenoid Methylenecyclohexanes

Allylic alcohols 3 and 4 have been prepared and activated toward formation of allyl cations, giving 3-methylenebicyclooct-6-enes 7 and 9, respectively, in the presence of cyclopentadiene; with furan, not only the products of conventional electrophilic substitution 11 and 13 are formed, but also 3-methylene-8-oxabicyclooct-6-enes 12 and 14.

Rhodium(III)-catalyzed olefinic C-H alkynylation of acrylamides using tosyl-imide as directing group

The Rh(III)-catalyzed C-H alkynylation of acrylamide derivative is realized using a hypervalent alkynyl iodine reagent. The use of a weakly coordinating directing group proved to be of critical importance. This reaction displays broad functional group tolerance and high efficiency, which opens a new synthetic pathway to access functionalized 1,3-enyne skeletons.

HIGH YIELD SYNTHESIS OF α PROPARGYLIC ACRYLIC ESTER : A GENERAL ACCESS TO α SUBSTITUTED ACRYLIC ESTERS

A heterogeneous mediated, high yield, monopropargylation of ethyl benzoylacetate followed by a methylenation reaction using a formaldehyde addition-benzoyl elimination mechanism is described.This useful method is extended to the synthesis of α substituted acrylic esters.

ISOLEMENT DU "REACTIF DE REFORMATSKY" DERIVE DE L'α-(BROMOMETHYL) ACRYLATE D'ETHYLE

The organozinc reagent derived from ethyl α-(bromomethyl) acrylate is prepared at 17 deg C T 20 deg C (duplication 10percent) and then coupled efficiently with nucleophilic imines to give α-methylene γ-lactames with high yields.