18243-41-9

Basic information

• Product Name: (BROMOMETHYL)TRIMETHYLSILANE
• Synonyms: (bromomethyl)trimethyl-silan;(BROMOMETHYL)TRIMETHYLSILANE;(TRIMETHYLSILYL)METHYL BROMIDE;Bromo(trimethylsilyl)methane
• CAS NO: 18243-41-9
• Molecular Formula: C₄H₁₁BrSi
• Molecular Weight: 167.12
• Product Categories: Si (Classes of Silicon Compounds);Si-(C)4 Compounds;Silicon Compounds (for Synthesis);Synthetic Organic Chemistry
• Mol File: 18243-41-9.mol

Chemical Properties

• Boiling Point: 115.5 °C742 mm Hg(lit.)
• Flash Point: 61 °F
• Appearance: /
• Density: 1.17 g/mL at 25 °C(lit.)
• Vapor Pressure: 21.6mmHg at 25°C
• Refractive Index: n20/D 1.444(lit.)
• BRN: 1731484
• CAS DataBase Reference: (BROMOMETHYL)TRIMETHYLSILANE(CAS DataBase Reference)
• NIST Chemistry Reference: (BROMOMETHYL)TRIMETHYLSILANE(18243-41-9)
• EPA Substance Registry System: (BROMOMETHYL)TRIMETHYLSILANE(18243-41-9)

Safety Data

• Hazard Codes: F,C
• Statements: 11-34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 2924 3/PG 2
• WGK Germany: 3
• F: 21
• TSCA: Yes
• HazardClass: 3.1
• PackingGroup: II
• Hazardous Substances Data: 18243-41-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Production:
(BROMOMETHYL)TRIMETHYLSILANE is used as a reagent in the synthesis of pharmaceuticals for its ability to introduce specific functional groups into organic molecules, which can enhance the properties and effectiveness of the resulting drugs.
Used in Polymer Modification:
In the polymer industry, (BROMOMETHYL)TRIMETHYLSILANE serves as a reagent for modifying polymers, allowing for the alteration of their chemical and physical properties to meet specific application requirements.
Used in Organosilicon Compound Synthesis:
(BROMOMETHYL)TRIMETHYLSILANE is utilized as a starting material or intermediate in the synthesis of other organosilicon compounds, which have a wide range of applications in various industries due to their unique properties.
It is crucial to handle (BROMOMETHYL)TRIMETHYLSILANE with caution due to its high reactivity and potential toxicity if not used properly.

InChI:InChI=1/C4H11BrSi/c1-6(2,3)4-5/h4H2,1-3H3

Upstream product

• 16532-02-8 bromomethyldimethylsilyl chloride 
• 75-16-1 methylmagnesium bromide 
• 109-65-9 1-bromo-butane 
• 4206-67-1 iodo(trimethylsilyl)methane 
• 18297-50-2 ((trimethylsilyl)methyl)trimethylstannane 
• 18143-91-4 dimethyl-(trimethylsilanyl-methyl)-tin ⁽¹⁺⁾; bromide 
• 75-76-3 tetramethylsilane 
• 7726-95-6 bromine 
• 186581-53-3 diazomethane 
• 2857-97-8 trimethylsilyl bromide 
• 2344-80-1 Chloromethyltrimethylsilane 
• 2612-42-2 (dibromomethyl)trimethylsilane 
• 542-69-8 1-iodo-butane 

Downstream Products

• 18752-91-5 triphenyl-(trimethylsilanyl-methyl)-phosphonium; bromide 
• 17962-38-8 diethyl<(trimethylsilyl)methyl>malonate 
• 17890-12-9 N-Phenyl-N-<(trimethylsilyl)methyl>amine 
• 51951-99-6 N-benzyl-N-methyl-1-(trimethylsilyl)methanamine 
• 55811-60-4 Furan-2-ylmethyl-trimethyl-silane 
• 1293988-75-6 rac-methylphenyl(piperidinomethyl)[(trimethylsilyl)methyl]silane 
• 1172-76-5 1,2-dimethyl-1,1,2,2-tetraphenyldisilane 
• 18057-47-1 Si,Si,Si,Si'-tetramethyl-Si',Si'-diphenyl-Si,Si'-methanediyl-bis-silane 
• 17988-20-4 (4-methoxy-benzyl)-trimethyl-silane 

Relevant articles and documents

Radical Silyldifluoromethylation of Electron-Deficient Alkenes

A reaction of bromo- and iododifluoromethyl-substituted silanes with electron-deficient alkenes in the presence of an N-heterocyclic carbene borane complex is described. The reaction is performed under irradiation with light-emitting diodes and proceeds v

Preparation of (Trimethylsilyl)methyl Halides and Trifluoromethanesulfonate by Methylene Insertion Using Diazomethane

(Trimethylsilyl)methyl halides (1,3) and trifluoromethanesulfonate (triflate) (2) were prepared by inserting a methylene group into the silicon-heteroatom bond of trimethylsilyl halides and triflate using diazomethane.

LEWIS ACID CATALYZED HALOGENATION OF ACTIVATED CARBON ATOMS

A practical and efficient method for halogenation of activated carbon atoms using readily available /V-haloimides and a Lewis acid catalyst has been disclosed. This methodology is applicable to a range of compounds and any halogen atom can be directly introduced to the substrate. The mild reaction conditions, easy workup procedure and simple operation make this method valuable from both an environmental and preparative point of view.

Electrophilic cleavages in (CH3)3SnCH2M(CH3)3 (M = Sn, Ge, Si, C). 1. Product distribution

The extent to which Sn-CH2 and/or Sn-CH3 cleavage occurs in (CH3)3SnCH2M(CH3)3 (M = Sn, Ge, Si) in reactions with several electrophiles has been determined. With iodine and with

STABILIZATION IN THE ORDER I>Br>Cl AMONG TRIMETHYLSILYLMETHYL HALIDES, COMPARED TO CARBON ANALOGS. POSSIBLE ROLE OF ELECTRONEGATIVITY IN ORGANOSILICON CHEMISTRY

Electronegativities may be used to rationalize the observation that the equilibrium, CH3(CH2)3I + (CH3)3SiCH2Cl CH3(CH2)3Cl + (CH3)3SiCH2I, lies to the right.