cas 18362-30-6, 2-CHLORO-6-HYDROXYBENZALDEHYDE

Articles about 18362-30-6Total 18 be found

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Bunnett et al.
p. 2512,2513
(1961)
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Resolution of 2,3-dihydro-benzofuran-3-ols
A new method for the preparation of enantiopure 2,2-disubstituted 2,3-dihydro-benzofuran-3-ols is described. A short synthesis is designed for obtaining various 2,2-disubstitued benzofuran-3-ols as racemic mixtures of the two possible syn and anti diastereoisomers, which can be separated after silylation. The major racemic anti isomers were transesterified using (R) -pentolactone, allowing separation of the pure enantiomers. Indian Academy of Sciences.
Charrier, Cedric,Bertrand, Philippe
p. 459 - 466
(2011)
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Postmus,C. et al.
p. 2693 - 2698
(1964)
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METHOD FOR PREPARING 3-SUBSTITUTED 2-VINYLPHENYL SULFONATES
The present invention relates to a method for preparing 3-substituted 2-vinylphenyl sulfonates.
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Paragraph 0080-0084

(2020/03/23)

PROCESS FOR PREPARING 3-CHLORO-2-VINYLPHENYLSULFONATES
The present invention relates to a new process for preparing 3-chloro-2-vinylphenylsulfonate derivatives.
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(2018/04/14)

A Strategy toward Icetexane Natural Products
Icetexane diterpenoids are richly complex polycyclic natural products that have been described with a variety of biological activities. We report here a general synthetic approach toward the 6-7-6 tricyclic core structure of these interesting synthetic ta
Moon, Daniel J.,Al-Amin, Mohammad,Lewis, Robert S.,Arnold, Kimberly M.,Yap, Glenn P. A.,Sims-Mourtada, Jennifer,Chain, William J.
supporting information
p. 3348 - 3351
(2018/07/13)

Pd-Catalyzed Ortho C-H Hydroxylation of Benzaldehydes Using a Transient Directing Group
The direct Pd-catalyzed ortho C-H hydroxylation of benzaldehydes was achieved using 4-chloroanthranilic acid as the transient directing group, 1-fluoro-2,4,6-trimethylpyridnium triflate as the bystanding oxidant, and p-toluenesulfonic acid as the putative oxygen nucleophile. The unusual C-H chlorination and polyfluoroalkoxylation reactions signaled the importance of external nucleophiles to the outcome of Pd(IV) reductive eliminations.
Chen, Xiao-Yang,Ozturk, Seyma,Sorensen, Erik J.
supporting information
p. 6280 - 6283
(2017/12/08)

Aldehyde-Assisted Ruthenium(II)-Catalyzed C-H Oxygenations
Versatile ruthenium(II) complexes allow for site-selective C-H oxygenations with weakly-coordinating aldehydes. The challenging C-H functionalizations proceed with high chemoselectivity by rate-determining C-H metalation. The new method features an ample substrate scope, which sets the stage for the step-economical preparation of various bioactive heterocycles.
Yang, Fanzhi,Rauch, Karsten,Kettelhoit, Katharina,Ackermann, Lutz
supporting information
p. 11285 - 11288
(2016/02/18)

2-CARBOXAMIDE-4-PIPERAZINYL-BENZOFURAN DERIVATIVE
The present invention relates to a compound of formula (I), and to pharmaceutical compositions containing said compound and to the use of said compound in therapy, for instance in treating cognitive disorders, as well as to intermediates useful in the preparation thereof.
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Page/Page column 14

(2012/07/13)

INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
Compounds of formula (I): wherein R4, R6 and R7 are defined herein, are useful as inhibitors of HIV replication.
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Page/Page column 72-73

(2009/06/27)

INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
Compounds of formula (I): wherein c, X, Y, R2, R4 and R5 are defined herein, are useful as inhibitors of HIV replication.
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Page/Page column 81; 83

(2009/06/27)

INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
The present invention relates to compounds of formula (I) wherein c, X, Y, R2, R3, R4 and R6 are as defined herein, compositions and uses thereof for treating human immunodeficiency virus (HIV) infection. In particular, the present invention provides novel inhibitors of HIV integrase, pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HIV infection
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Page/Page column 78; 80

(2009/06/27)

INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
Compounds of formula I : wherein c, R2, R3, R4, R5, R6, R7 and R8 are defined herein, are useful as inhibitors of HIV replication.
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Page/Page column 85; 86-87

(2009/06/27)

Certain pyrazoline derivatives with kinase inhibitory activity
The present invention provides certain pyrazoline compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutical compositions and methods of using the compositions in the treatment of various diseases.
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Page/Page column 89

(2008/12/06)

Non-metallocene compounds, method for the production thereof and use of the same for the polymerisation of olefins
The invention relates to a method for producing special transition metal compounds, to novel transition metal compounds and to the use of the same for the polymerisation of olefins.
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(2008/06/13)

Convenient Method for the ortho-Formylation of Phenols
Phenolic derivatives are formylated selectively ortho to the hydroxy group by paraformaldehyde with magnesium dichloride-triethylamine as base. With alkyl-substituted phenols excellent yields of the corresponding salicylaldehyde derivatives were obtained. Similar results were obtained with chloro-substituted phenols and with 3- and 4-methoxyphenol, while 2-methoxyphenol was unreactive. A good yield of methyl 3-formyl-4-hydroxybenzoate was obtained by this method as well, but generally phenols with electron-attracting groups reacted sluggishly; the long reaction times required caused the formation of by-products, particularly MOM-derivatives of the phenols.
Hofslokken, Nini U.,Skattebol, Lars
p. 258 - 262
(2007/10/03)

Enantiomeric Epoxidation of 4-Chlorostyrene with H2O2 catalysed by Robust Chloro Manganese(III) meso-5,10,15,20-Tetrakis Porphyrins
Three new chiral porphyrins bearing chloro and glucosyl groups are obtained by Lindsey's method; their chloro manganese(III) complexes are robust catalysts for the asymmetric epoxidation of 4-chlorostyrene with diluted hydrogen peroxide.
Vilain, Sandrine,Maillard, Philippe,Momenteau, Michel
p. 1697 - 1698
(2007/10/02)

Tailed Mn(III)-tetraarylporphyrins Bearing an Axial Ligand and/or a Carboxylic Group: Self-consistent Catalysts for H2O2 or NaOCl Alkene Epoxidation
Mn(III)-tetraarylprophyrins bearing either a heterocyclic nitrogen base axial ligand or a carboxylic acid group, covalently bonded to the porphyrin through a single flexible chain, have been synthesized.Their basic frame is that of the robust tetrakis(2,6-dichlorophenyl)porphyrin, and the chains are connected by ether or amido linkages to the ortho-positions of one meso-aryl group.Catalytic efficiency was tested in alkene epoxidations at 0 deg C under aqueous CH2Cl2 two-phase conditions in the presence of NaOCl (pH 10.5) or 30percent H2O2 (pH 4.5) as oxygen donors (ODs).Compound 4 bearing an imidazole ligand showed satisfactory catalytic activity in the presence of both ODs, whereas Mn(III)-porphyrins 5a-d bearing a covalently bonded carboxylate group are suitable for the activation of H2O2, and proved to be very efficient in the presence of an externally added axial ligand.Catalyst 6, featuring an imidazole ligand and a carboxylate group bonded on the 2,6-positions of the same meso-aryl group, is particularly efficient in alkene epoxidations promoted by 30percent H2O2 (initial rates up to 500 turnovers/min, overall turnovers up to 1200).A possible reaction mechanism for epoxidation catalysed by the bis-tailed Mn(III)-porphyrins is discussed.
Anelli, Pier Lucio,Banfi, Stefano,Legramandi, Francesco,Montanari, Fernando,Pozzi, Gianluca,Quici, Silvio
p. 1345 - 1358
(2007/10/02)

Herbicidal substituted benzoylsulfonamides
Compound of the formula STR1 in which A is O, S, or NR3 ; G is CH or N; R and R1 are independently alkyl, alkoxy, haloalkoxy or alkylamino; R2 is phenyl, substituted phenyl, alkyl, cycloalkyl, haloalkyl or --CH2 [(R4)C(R5)n --Z; R3 and R7 are, independently, hydrogen, alkyl, --C(O)NH2 or --C(O)alkyl; R4 and R5 are independently hydrogen, alkyl, or halogen; R6 is halogen, alkyl, alkoxy, haloalkoxy, NO2, amino, alkyl substituted amino, or acyl substituted amino; n is 0 to 5; Z is cyano, amino, alkylamino, dialkylamino, --NHCO2 alkyl, alkoxy, alkylthio, alkylsulfonyl, alkenyl, alkynyl, phenyl or substituted phenyl; and Q is hydrogen, halogen, alkyl, alkoxy, haloalkoxy, nitro, amino, haloalkyl, alkythio, alkylsulfonyl, phenyl, substituted phenyl or phenoxy; or a 5 or 6 membered aromatic heterocycle having the formula STR2 in which "m" is 0 or 1; A' is O, S, or NR7 ; and X, X', Y, Y', W, W', V, V', U and Z' are independently N, O, S, --CH-- or --CR6. Intermediates for preparation of the benzoylsulfonamides are also disclosed.
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(2008/06/13)

SYNTHESIS AND REACTIONS OF SOME CHLORO-2,2-DIMETHYLCHROMENS
5-, 6-, 7-, and 8-Chloro-2,2-dimethylchromens have been prepared from the corresponding chlorocumarin and their conversion into the 3,4-dihalogenochroman derivatives is described.The 4-halogen atom is shown to be the more susceptible to hydrolysis by conv
Hepworth, John D.,Jones, Terry K.,Livingstone, Robert
p. 2613 - 2616
(2007/10/02)