18457-79-9Relevant articles and documents
Graphene oxide as an active carbocatalyst for cyanation of quinoline and isoquinoline N-Oxides
Huang, Panpan,Peng, Xiangjun,Qiu, Genhong,Yu, Keyang,Li, Hong,Kong, Lingting,Hu, Jiaming,Chen, Zhengwang,Huang, Qing,Liu, Liangxian
, (2021/02/16)
Graphene oxide was found to be a highly efficient and cost-effective heterogeneous catalyst for the direct metal-free transformation of quinoline and isoquinoline N-oxides into the corresponding nitriles under mild conditions. This method is simple, econo
Palladium(II)-mediated nucleophilic cyanation of 4-substituted quinoline 1-oxide in tue presence of trimethylsilyl cyanide and an oxidant
Tagawa, Yoshinobu,Higuchi, Yoshitaka,Yamagata, Kenji,Shibata, Kazuhiko,Teshima, Daisuke
, p. 2859 - 2862 (2007/10/03)
Reaction of 4-substituted (electron-releasing group) quinoline 1-oxides (1) with trimethylsilyl cyanide in the presence of palladium(II) acetate and DDQ gave 2-cyano-4-substituted quinoline 1-oxides (2) in THF in moderate yields. It was reasoned that this