18650-13-0

Basic information

• Product Name: 2,15-HEXADECANEDIONE
• Synonyms: HEXADECANE-2,15-DIONE;2,15-HEXADECANEDIONE
• CAS NO: 18650-13-0
• Molecular Formula: C₁₆H₃₀O₂
• Molecular Weight: 254.41
• EINECS: 242-588-3
• Mol File: 18650-13-0.mol

Chemical Properties

• Melting Point: 84-88 °C
• Boiling Point: 353.107 °C at 760 mmHg
• Flash Point: 132.487 °C
• Appearance: /
• Density: 0.887 /cm³
• Vapor Pressure: 1.57E-05mmHg at 25°C
• Refractive Index: 1.634
• CAS DataBase Reference: 2,15-HEXADECANEDIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,15-HEXADECANEDIONE(18650-13-0)
• EPA Substance Registry System: 2,15-HEXADECANEDIONE(18650-13-0)

Safety Data

• Safety Statements: 22-24/25
• Hazardous Substances Data: 18650-13-0(Hazardous Substances Data)

Usage

Uses

Used in Food Industry:
2,15-Hexadecanedione is used as a flavoring agent for enhancing the taste and aroma of food products, particularly in the production of butter and cream flavors. Its creamy, buttery scent adds richness and depth to a variety of culinary creations.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 2,15-Hexadecanedione is utilized for its pleasant odor and flavoring properties, potentially improving the palatability of certain medications and contributing to a better patient experience.
Used in Cosmetic Industry:
The cosmetic industry also leverages 2,15-Hexadecanedione as a component in fragrances and scented products, capitalizing on its appealing aroma to create more attractive and enjoyable consumer products.

InChI:InChI=1/C18H18/c1-18(2,3)17-9-8-15-10-13-6-4-5-7-14(13)11-16(15)12-17/h4-12H,1-3H3

Upstream product

• 872308-32-2 1,16-dichlorohexadecane-2,15-dione 
• 141-97-9 ethyl acetoacetate 
• 4101-68-2 1,10-dibromodecane 
• 1007476-32-5 sodium ethyl acetylacetate enolate 
• 23560-06-7 hexadecane-2,15-diol 
• 78-94-4 methyl vinyl ketone 
• 3710-30-3 1,7-Octadiene 
• 23548-86-9 (S,S)-hexadecane-2,15-diol 
• 110073-90-0 2,15-dihydroxy-2,15-di(1-methy-1H-imidazol-2-yl)hexadecane 
• 3922-28-9 1,12-dichlorododecane 
• 75-36-5 acetyl chloride 
• 33965-97-8 tetradec-13-en-2-one 
• 13483-31-3 Acetone dimethylhydrazone 
• 60419-54-7 hexadeca-6t,10t-diene-2,15-dione 

Downstream Products

• 22442-01-9 3-methylcyclopentadecenone 
• 956-82-1 3-methylcyclopentadecanone 
• 22442-02-0 dehydromuscone 
• 10403-00-6 (R)-3-methyl-1-cyclopentadecanone 
• 94561-99-6 3-methylidene-cyclopentadecan-1-one 
• 58643-71-3 (Z)-3-methyl-2-cyclopentadecen-1-one 
• 58643-70-2 (E)-3-methyl-2-cyclopentadecenone(E)-3-methyl-2-cyclopentadecenone 
• 22442-02-0 (Z)-3-methylcyclopentadec-3-en-1-one 
• 58643-72-4 (E)-3-methylcyclopentadec-3-en-1-one 

Relevant articles and documents

METHOD FOR PRODUCING 3-METHYLCYCLOALKENONE COMPOUND

The present invention relates to a method for producing a 3-methylcycloalkenone compound and a method for producing muscone. In the presence of a zirconium oxide catalyst, a diketone represented by the following general formula (1): wherein in formula (1), n represents 8, 9, 10, 11 or 12, is subjected to a vapor-phase intramolecular condensation reaction, whereby a 3-methylcycloalkenone compound can be produced with high reaction efficiency. When a 3-methylcyclopentadecenone compound produced by this method is hydrogenated in a known manner, muscone can be produced efficiently.

METHOD FOR CONVERTING HYDROXYL GROUP OF ALCOHOL

The present invention relates to: a method for converting a hydroxyl group of an alcohol; and a catalyst which makes the method possible. A method for converting a hydroxyl group of an alcohol according to the present invention is characterized by producing a compound represented by CH(R1)(R2)Nu (wherein R1, R2 and Nu are as defined below) by reacting an alcohol represented by CH(R1)(R2)OH (wherein each of R1 and R2 represents a hydrogen atom, an optionally substituted alkyl group, or the like) and a compound having an active proton, which is represented by H-Nu (wherein Nu represents a group represented by —CHX1-EWG1 or —NR3R4; X1 represents a hydrogen atom or the like; EWG1 represents an electron-withdrawing group; and each of R3 and R4 represents a hydrogen atom, an optionally substituted alkyl group, or the like), with each other in the presence of a complex of a group 7-11 metal of the periodic table and at least one solid base that is selected from the group consisting of layered double hydroxides, composite oxides and calcium hydroxide.

Highly productive α-alkylation of ketones with alcohols mediated by an Ir-oxalamidato/solid base catalyst system

An Ir-oxalamidato complex in combination with a solid base (e.g., magnesium aluminometasilicate/Ca(OH)2) significantly improved the catalyst productivity in α-alkylation of methyl ketones with primary alcohols. Optimization through systematic variation of the oxalamidato ligand led to a practical turnover number (TON) of 10 000.40 000.

2, 15 - 3 - And production of purification of hexadecane dione [...]

2, 15 - Hexadecane dione [to] with high yield, high-purity purification method for purifying 2, 15 - hexadecane dione, moreover, 3 - [...] allyl, high yield production of 3 - can be [...]. The present invention is method for purifying 2, 15 - [solution] hexadecane dione, acetoacetic ester is reacted with an alkali metal salt of 1, 10 - [...] then, sulfuric acid produced by the method of purification of 2, 15 - hexadecane dione decarboxylation, 1.0 mass % or less at a rate of 10.0% by mass including water, methanol and water by using a mixed solvent, wherein 2, 15 - hexadecane dione characterized by recrystallizing. [Drawing] no

Synthesis method of long-chain diketone

The invention discloses a synthesis method of long-chain diketone. The method comprises the following steps: by taking alpha, omega-diol as an alkylating agent, under the catalysis of a metal carriedby a carrier and a metal oxide, alkylating acetone, thus obtaining a long-chain diketone product. According to the synthesis method, a ruthenium-sodium oxide catalyst carried by silicon oxide is used,and the catalyst also has the catalytic activities such as dehydrogenation, aldol condensation and hydrogenization, so that the synthesis of the diketone is realized by one step; no extra alkali is added into the system; the catalyst is high in activity and can be recycled and reused. Compared with a known synthesis method, the synthesis method disclosed by the invention is simple and efficient in reaction by taking the alpha, omega-diol and the acetone which are low in cost as starting raw materials, and only water which is a byproduct is produced, so that the synthesis method is economical,environmentally friendly and suitable for scale-up synthesis of the long-chain diketone.

METHOD FOR PRODUCING ALKALI SALT OF ACETOACETIC ESTER AND METHOD FOR PRODUCING ALIPHATIC DIKETONE

PROBLEM TO BE SOLVED: To provide a method for producing an alkali salt of acetoacetic ester that can produce an alkali salt of acetoacetic ester in a high yield. SOLUTION: In producing an alkali salt of acetoacetic ester represented by the formula of (CH3COCHCOOR)-M+, provided that in the formula, R is a methyl group or an ethyl group; and M is sodium or potassium, firstly a nonprotonic organic solvent optionally miscible with water and an acetoacetic ester are mixed. In a state the nonprotonic organic solvent and the acetoacetic ester being mixed, an alkali hydroxide compound is added and reacted. As the nonprotonic organic solvent optionally miscible with water, at least one kind of acetone, tetrahydrofuran and acetonitrile is preferably used. SELECTED DRAWING: None COPYRIGHT: (C)2018,JPOandINPIT

RUBBER COMPOSITION, TIRE, AMINE COMPOUND, AND ANTI-AGING AGENT

Provided is a rubber composition that has better weather resistance than conventional rubber compositions and can inhibit surface discoloration of a rubber article. The rubber composition contains at least one rubber component selected from natural rubber and diene-based synthetic rubbers and, blended therewith, at least one amine compound represented by formula (I) shown below. In formula (I), R1 and R2 each represent, independently of one another, an alkyl group having a carbon number of 1-10, an aralkyl group, or a phenyl group, and A represents an alkylene group having a carbon number of 6-30 that may include an interposed phenylene group.

METHOD FOR PRODUCING 3-METHYL CYCLOPENTADECENONES

PROBLEM TO BE SOLVED: To provide a method for producing 3-methyl cyclopentadecenones in which the 3-methyl cyclopentadecenones can efficiently be produced. SOLUTION: The 3-methylcyclopentadecenones is produced by an intramolecular condensation reaction of 2,15-hexadecanedione represented by the chemical formula of CH3CO(CH2)12 COCH3. And, in the intramolecular condensation reaction, by using a catalyst having a BET specific surface area of 10 m2/g or less, a decrease in yield due to an increase of the intermolecular condensation reaction on the catalyst can be suppressed as well as, because the deterioration of catalyst can be suppressed, 3-methylcyclopentadecenones can efficiently be produced by the intramolecular condensation reaction. Further, the catalyst is preferably at least one of magnesium oxide, calcium oxide and zinc oxide. SELECTED DRAWING: None COPYRIGHT: (C)2017,JPOandINPIT

PROCESS FOR PRODUCTION OF 3-METHYL-CYCLOPENTADECENONE, PROCESS FOR PRODUCTION OF R/S-MUSCONE, AND PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE MUSCONE

By intramolecular condensation reaction of 2,15-hexadecanedione in a gaseous phase with a compound of a Group II element of the Periodic Table as a catalyst, 3-methyl-cyclopentadecenones is generated. Magnesium oxide, calcium oxide, or zinc oxide is desirable as the catalyst for the intramolecular condensation reaction. (R)- and (S)-muscone is generated by subjecting 3-methyl-cyclopentadecenones obtained as above to hydrogenation by using a catalyst. Palladium catalyst is desirable as the hydrogenation catalyst. Optically active muscone is generated by separating 3-methyl-cyclopentadecenones into respective components thereof by means of precision distillation and subsequently subjecting the separated 3-methyl-cyclopentadecenones to asymmetric hydrogenation by using an optically active ruthenium complex catalyst. The production methods described above enable easy and economical production of 3-methyl-cyclopentadecenones, (R)-and (S)-muscone, and optically active muscone.

METHOD FOR PRODUCING 3-METHYL-CYCLOPENTADECENONES, METHOD FOR PRODUCING (R)- AND (S)- MUSCONE, AND METHOD FOR PRODUCING OPTICALLY ACTIVE MUSCONE

By intramolecular condensation reaction of 2,15-hexadecanedione in a gaseous phase with a compound of a Group II element of the Periodic Table as a catalyst, 3-methyl-cyclopentadecenones is generated. Magnesium oxide, calcium oxide, or zinc oxide is desirable as the catalyst for the intramolecular condensation reaction. (R)- and (S)-muscone is generated by subjecting 3-methyl-cyclopentadecenones obtained as above to hydrogenation by using a catalyst. Palladium catalyst is desirable as the hydrogenation catalyst. Optically active muscone is generated by separating 3-methyl-cyclopentadecenones into respective components thereof by means of precision distillation and subsequently subjecting the separated 3-methyl-cyclopentadecenones to asymmetric hydrogenation by using an optically active ruthenium complex catalyst. The production methods described above enable easy and economical production of 3-methyl-cyclopentadecenones, (R)- and (S)-muscone, and optically active muscone.