22198-54-5Relevant articles and documents
Asymmetric reduction of α-thiocyanatoketones by Saccharomyces cerevisiae and Mortierella isabellina-a new route to optically active thiiranes
Lukowska, Edyta,Plenkiewicz, Jan
, p. 1202 - 1209 (2008/02/05)
A simple method for the preparation of optically active 1-aryloxy- and 1-arylsulphanyl-3-thiocyanatopropan-2-oles from racemic 1-chloro-3-aryloxy- and 1-chloro-3-arylsulphanyl-2-propanols via 1-aryloxy- and 1-arylsulphanyl-3-thiocyanatopropan-2-ones has been developed. The enantiomerically enriched β-hydroxythiocyanates were obtained by a microbiological reduction of the thiocyanatoketones with Saccharomyces cerevisiae or Mortierella isabellina and subsequently converted into optically active thiiranes on treatment with a lithium hydroxide solution.
Synthesis of Enantiomerically Pure (4S)-2-Alken-4-olides via (2S)-1-Phenylsulfonyl-2-alkanols
Tanikaga, Rikuhei,Hosoya, Ken,Kaji, Aritsune
, p. 389 - 390 (2007/10/02)
Reduction of 1-chloro-3-phenylsulfonyl-2-propanone with baker's yeast, followed by epoxidation and alkylation with Grignard reagents, yields enantiomerically pure (2S)-2-phenylsulfonyl-2-alkanols, which are converted into (4S)-2-alken-4-olides in 100perce
Synthesis of Enantiomerically Pure 2,5-Disubstituted Teterahydrofurans Using Readily Prepared (2S)-1-Phenylsulphonylalkan-2-ols
Tanikaga, Rikuhei,Hosoya, Ken,Kaji, Aritsune
, p. 1799 - 1804 (2007/10/02)
Enantiomerically pure (2S)-1-phenylsulphonylalkan-2-ols have been prepared from 1-chloro-3-phenylsulphonylpropan-2-one (2) by the folloving successive procedures: reduction with baker's yeast, epoxidation with silver(I) oxide, and alkylation with