22826-55-7

Basic information

• Product Name: (N,N-DiMethylaMinoMethyl)styrene
• Synonyms: 2-Vinyl-N,N-dimethylbenzylamine;2-(Dimethylaminomethyl)styrene;N,N-DIMETHYL-2-VINYLBENZYLAMINE;(N,N-DiMethylaMinoMethyl)styrene;N,N-Dimethyl-1-(2-vinylphenyl)methanamine
• CAS NO: 22826-55-7
• Molecular Formula: C₁₁H₁₅N
• Molecular Weight: 161.2435
• EINECS: -0
• Product Categories: Chloromethy styrene
• Mol File: 22826-55-7.mol

Chemical Properties

• Boiling Point: 212.9℃
• Flash Point: 74.7℃
• Appearance: /
• Density: 0.937
• Storage Temp.: 2-8°C
• PKA: 8.69±0.28(Predicted)
• CAS DataBase Reference: (N,N-DiMethylaMinoMethyl)styrene(CAS DataBase Reference)
• NIST Chemistry Reference: (N,N-DiMethylaMinoMethyl)styrene(22826-55-7)
• EPA Substance Registry System: (N,N-DiMethylaMinoMethyl)styrene(22826-55-7)

Safety Data

• Hazardous Substances Data: 22826-55-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(N,N-DiMethylaMinoMethyl)styrene is used as a pharmaceutical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential therapeutic benefits.
Used in Pharmaceutical Experimental Research:
(N,N-DiMethylaMinoMethyl)styrene is utilized in pharmaceutical experimental research to explore its potential applications and properties. This research can lead to a better understanding of its role in drug development and the discovery of new therapeutic agents.

InChI:InChI=1S/C11H15N/c1-4-10-7-5-6-8-11(10)9-12(2)3/h4-8H,1,9H2,2-3H3

Upstream product

• 24489-94-9 2,2-dimethyl-1,2,3,4-tetrahydro-isoquinolinium; chloride 
• 1637-45-2 2,2-dimethyl-1,2,3,4-tetrahydroisoquinolinium iodide 
• 83781-70-8 2,2-dimethyl-4-(trimethylsilyl)-1,2,3,4-tetrahydroisoquinolinium iodide 
• 134753-82-5 2-methyl-2-<(trimethylsilyl)methyl>-1,2,3,4-tetrahydroisoquinolinium iodide 
• 74-85-1 ethene 
• 1612-65-3 2-methyl-1,2,3,4-tetrahydroisoquinoline 
• 83781-69-5 2-methyl-4-(trimethylsilyl)-1,2,3,4-tetrahydroisoquinoline 
• 119-65-3 isoquinoline 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 19886-78-3 1-formyl-2-[(dimethylamino)methyl]benzene 
• 52728-16-2 2-(dimethylaminomethylphenyl)ethylbenzene 
• 90031-80-4 trimethyl-(2-vinyl-benzyl)-ammonium; iodide 
• 14761-82-1 2-(2-dimethylaminomethylphenyl)ethanol 
• 52728-18-4 1-(2-dimethylaminomethylphenyl)ethanol 
• 1467-79-4 NCNMe₂ 
• 22570-84-9 2-chloromethylstyrene 
• 6196-39-0 1-(2-benzylphenyl)-N,N-dimethylmethanamine 
• 6969-97-7 2--benzhydrol 

Relevant articles and documents

Hoveyda–Grubbs catalysts with an N→Ru coordinate bond in a six-membered ring. Synthesis of stable, industrially scalable, highly efficient ruthenium metathesis catalysts and 2-vinylbenzylamine ligands as their precursors

A novel and efficient approach to the synthesis of 2-vinylbenzylamines is reported. This involves obtaining 2-vinylbenzylamine ligands from tetrahydroisoquinoline by alkylation and reduction followed by the Hofmann cleavage. The resultant 2-vinylbenzyl-amines allowed us to obtain new Hoveyda–Grubbs catalysts, which were thoroughly characterised by NMR, ESIMS, and X-ray crystallography. The utility of this chemistry is further demonstrated by the tests of the novel catalysts (up to 10?2 mol %) in different metathesis reactions such as cross metathesis (CM), ring-closing metathesis (RCM) and ring-opening cross metathesis (ROCM).

GROUP 8 TRANSITION METAL CATALYSTS AND METHOD FOR MAKING SAME AND PROCESS FOR USE OF SAME IN OLEFIN DISPROPORTIONATION REACTIONS

These catalyst compounds are represented by the formula (I and VI): wherein M is a Group 8 metal; X is an anionic ligand; L is a neutral two-electron donor ligand; A is a monotopic or ditopic chelating ligand. The present invention also relates to an easy applicable catalyst synthesis and the application in different olefin metathesis processes, e.g. Reaction Injection Molding (RIM), rotational molding, vacuum infusion, vacuum forming, process for conversion of fatty acids and fatty acid esters or mixtures thereof, in -olefins, dicarboxylic acids or dicarboxylic esters, etc.

Determining the scope of the lanthanide mediated, sequential hydroamination/C-C cyclization reaction: Formation of tricyclic and tetracyclic aromatic nitrogen heterocycles

The scope of the lanthanide mediated, sequential hydroamination/C-C cyclization reaction was determined for the formation of tricyclic and tetracyclic aromatic nitrogen heterocycles. An array of ring sizes was explored to determine the diastereoselectivity. The electronic characteristics of the aromatic ring was also varied to determine how it affected the cascade reaction. It was found that the benzo[a]quinolizine and the pyrido[2,1,a]isoindolizine ring systems formed with the highest diastereoselectivity (>20:1), regardless of the electronic characteristics of the aromatic ring. Additionally, a tetracyclic indole nitrogen heterocycle was formed with a 2.3:1 diastereomeric ratio. A novel procedure for substrate preparation is also presented.

Cycloruthenated tertiary amines and ethylene: Further insight to the Ru- mediated olefin-aryl coupling reaction

The reaction between cycloruthenated N,N-dimethylbenzylamine and ethylene under very mild conditions afforded 2-vinyl-N,N-dimethylbenzylamine and an organometallic Ru derivative resulting from the overall insertion of one carbon atom in the Ru-C bond of t

Rearrangements of 1,6,7-Trisubstituted 2-Methyl-1,2,3,4-tetrahydroisoquinolinium 2-Methylides

Chemical behavior of 1,6,7-trisubstituted 2-methy-1,2,3,4-tetrahydroisoquinolinium 2-methylides 4 was investigated in fluoride-ion induced desilation reaction of 1,6,7-trisubstituted 2-methyl-2-(trimethylsilyl)methyl-1,2,3,4-tetrahydroisoquinolinium iodid

HYDROBORATION OF N,N-DIMETHYL(2-VINYLBENZYL)AMINE

Hydroboration of N,N-dimethyl(2-vinylbenzyl)amine followed by oxidation afforded a mixture of primary and secondary alcohol, i.e. 2-(2-dimethylaminomethylphenyl)ethanol and 1-(2-dimethylaminomethylphenyl)ethanol, together with the reduction product - 2-et