2403-50-1

Basic information

• Product Name: p-Anisaldehyde ethylene acetal
• Synonyms: 2-(p-Methoxyphenyl)-1,3-dioxolane;4-Methoxybenzaldehyde ethylene acetal;p-Anisaldehyde (ethane-1,2-diyl)acetal;p-Anisaldehyde ethylene acetal
• CAS NO: 2403-50-1
• Molecular Formula: C₁₀H₁₂O₃
• Molecular Weight: 180.2
• Mol File: 2403-50-1.mol

Chemical Properties

• Boiling Point: 281.1°C at 760 mmHg
• Flash Point: 93.1°C
• Appearance: /
• Density: 1.133g/cm³
• Vapor Pressure: 0.00619mmHg at 25°C
• Refractive Index: 1.517
• CAS DataBase Reference: p-Anisaldehyde ethylene acetal(CAS DataBase Reference)
• NIST Chemistry Reference: p-Anisaldehyde ethylene acetal(2403-50-1)
• EPA Substance Registry System: p-Anisaldehyde ethylene acetal(2403-50-1)

Safety Data

• Hazardous Substances Data: 2403-50-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H12O3/c1-11-9-4-2-8(3-5-9)10-12-6-7-13-10/h2-5,10H,6-7H2,1H3

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 107-21-1 ethylene glycol 
• 13807-89-1 2-(4-methoxybenzyloxy)ethanol 
• 122-51-0 orthoformic acid triethyl ester 
• 105-13-5 4-Methoxybenzyl alcohol 
• 646-06-0 1,3-DIOXOLANE 
• 623-12-1 4-chloromethoxybenzene 
• 7381-30-8 2,2,7,7-tetramethyl-3,6-dioxa-2,7-disilaoctane 
• 74733-99-6 2-<2-(2-methoxyethoxy)ethoxy>-1,3-dioxolan 
• 13139-86-1 4-methoxyphenyl magnesium bromide 

Downstream Products

• 3526-43-0 N-(4-methoxybenzyl)aniline 
• 57479-35-3 8-(4-methoxyphenyl)quinoline 
• 2017-87-0 ethyl (2E)-2-cyano-3-(4-methoxyphenyl)acrylate 
• 24588-72-5 2-(4-methoxyphenyl)-1,3-dithiane 
• 1449315-82-5 2-(tert-butylperoxy)-2-(4-methoxyphenyl)-1,3-dioxolane 
• 105-13-5 4-Methoxybenzyl alcohol 
• 6712-20-5 2-(4-methoxyphenyl)-[1,3]dithiolane 
• 7143-95-5 p-Methylbenzoesaeure-β-bromethylester 
• 24165-60-4 1-(4-methoxyphenyl)but-3-en-1-ol 
• 107-21-1 ethylene glycol 
• 121-98-2 methyl 4-methoxybenzoate 
• 23837-15-2 1-(bis(ethylthio)methyl)-4-methoxybenzene 
• 13807-89-1 2-(4-methoxybenzyloxy)ethanol 

Relevant articles and documents

Formation of dioxolane on the surface of silica-sulphuric acid in dry media - Chemoselective protection of aryl aldehydes

Chemoselective protection of aryl aldehydes can be accomplished through the formation of dioxolane on the surface of silica-sulphuric acid under solvent-free conditions where aliphatic aldehydes, dialkyl ketones, aryl alkyl ketones, and diaryl ketones rem

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Structure and surface properties of Ni-Al hydrotalcite-like compounds and their catalytic application in highly selective acetalization at room temperature

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The synthesis of a new fulleropyrrolidine-(tricarbonyl)chromium complex: 1-methyl-2-(4-methoxyphenyl)-3,4-[60]fulleropyrrolidine-(tricarbonyl)chromium is described together with its characterization by IR, NMR and cyclic voltammetry. IR spectro-electroche

Inhibition by Water during Heterogeneous Br?nsted Acid Catalysis by Three-Dimensional Crystalline Organic Salts

A new self-assembled and self-healing class of metal free, recyclable, heterogeneous Br?nsted acid catalysts has been developed by the protonation of aniline derivatives (tetrakis(4-aminophenyl)methane, leuco-crystal violet, benzidine, and p-phenylenediamine) with aromatic sulfonic acids (tetrakis(phenyl-4-sulfonic acid)methane, and 2,6-naphthalenedisulfonic acid). As a result, five three-dimensional crystalline organic salts (F-1a, F-1b, F-1c, F-2, and F-3) were obtained, linked by hydrogen bonds and additionally stabilized by the opposite charges of the components. Frameworks F-2 and F-3 were prepared for the first time and characterized by elemental analysis, X-ray structural analysis (for F-2), thermogravimetry, SEM, and FTIR spectroscopy. The catalytic activities of crystalline organic salts F-1-3 have been explored in industrially important epoxide ring-opening and acetal formation reactions. The presence of encapsulated water inside frameworks F-1a and F-2 had an inhibitory effect on the performance of the catalysts. X-ray diffraction analysis of hydrated and dehydrated samples of F-1a and F-2 indicated that water of crystallization served as a cross-linking agent, diminishing the substrate induced "breathing"affinities of the frameworks.

Application of poly(Vinylbenzyltrimethylammonium tribromide) resin as an efficient polymeric catalyst in the acetalization and diacetylation of benzaldehydes

The applications of a new supported tribromide reagent (poly(vinylbenzyltrimethylammonium tribromide) resin) were reported. This supported tribromide resin was used as a catalyst in the acetalization and diacetylation of benzaldehydes under mild conditions with high efficiency. The effects of solvents, and amount of the supported tribromide resin on the reactions were investigated. Under the optimal conditions, most of acetal and 1,1-diacetates of benzaldehydes were selectively obtained in excellent yields.

Alcohol Etherification via Alkoxy Radicals Generated by Visible-Light Photoredox Catalysis

A mechanistically divergent method is described that, employing a commercially available hypervalent iodine(III) reagent, generates alkoxy radicals from 1°, 2°, and 3° alcohols and allows their use in the functionalization of C(sp3)-H and C(sp2)-H bonds. This visible-light photoredox catalysis produces alkyl ethers via 1,5/6-hydrogen atom transfer or aryl ethers via 1,5-addition. This mild methodology provides a practical strategy for the synthesis of acetals, orthoesters, tetrahydrofurans, and chromanes.

Chemoselective Nucleophilic Functionalizations of Aromatic Aldehydes and Acetals via Pyridinium Salt Intermediates

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Highly regioselective α-formylation and α-acylation of BODIPY dyes via tandem cross-dehydrogenative coupling with in situ deprotection

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Utilization of 1,3-Dioxolanes in the Synthesis of α-branched Alkyl and Aryl 9-[2-(Phosphonomethoxy)Ethyl]Purines and Study of the Influence of α-branched Substitution for Potential Biological Activity

Syntheses of α-branched alkyl and aryl substituted 9-[2-(phosphonomethoxy)ethyl]purines from substituted 1,3-dioxolanes have been developed. Key synthetic precursors, α-substituted dialkyl [(2-hydroxyethoxy)methyl]phosphonates were prepared via Lewis acid mediated cleavage of 1,3-dioxolanes followed by reaction with dialkyl or trialkyl phosphites. The best preparative yields were achieved under conditions utilizing tin tetrachloride as Lewis acid and triisopropyl phosphite. Attachment of purine bases to dialkyl [(2-hydroxyethoxy)methyl]phosphonates was performed by Mitsunobu reaction. Final α-branched 9-[2-(phosphonomethoxy)ethyl]purines were tested for antiviral, cytostatic and antiparasitic activity, the latter one determined as inhibitory activity towards Plasmodium falciparum enzyme hypoxanthine-guanine-xanthine phosphoribosyltransfesase. In most cases biological activity was only marginal.