26543-05-5

Basic information

• Product Name: (S)-3-HYDROXY-2-METHYL-PROPIONIC ACID
• Synonyms: Sodium (S)-3-hydroxy-2-methylpropionate;Sodium (S)-β-hydroxyisobutyrate;(2S)-3-hydroxy-2-methylpropanoic acid;(S)-3-Hydroxy-2-Methylpropanoic acid;(S)-3-Hydroxy-2-methylpropionic acid sodium salt;(S)-β-Hydroxy-isobutyric acid sodium salt;S-HIBA
• CAS NO: 26543-05-5
• Molecular Formula: C₄H₈O₃
• Molecular Weight: 104.1
• Mol File: 26543-05-5.mol

Chemical Properties

• Boiling Point: 252.9°Cat760mmHg
• Flash Point: 121°C
• Appearance: /
• Density: 1.195g/cm³
• Vapor Pressure: 0.00292mmHg at 25°C
• Refractive Index: 1.455
• Storage Temp.: 2-8°C
• PKA: 4.46±0.10(Predicted)
• CAS DataBase Reference: (S)-3-HYDROXY-2-METHYL-PROPIONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-HYDROXY-2-METHYL-PROPIONIC ACID(26543-05-5)
• EPA Substance Registry System: (S)-3-HYDROXY-2-METHYL-PROPIONIC ACID(26543-05-5)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 26543-05-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(S)-3-Hydroxy-2-methyl-propionic acid is used as an active pharmaceutical ingredient for its potential therapeutic properties, such as lowering cholesterol levels. It is valued for its role in energy metabolism, which can contribute to the development of treatments for metabolic disorders.
Used in Chemical Intermediates:
In the chemical industry, (S)-3-HIBA serves as a crucial intermediate in the synthesis of various compounds. Its unique structure and functional groups make it a versatile building block for creating a range of chemical products, including specialty chemicals and performance materials.
Used in Food Industry:
Although not explicitly mentioned in the provided materials, given its natural occurrence in certain foods, (S)-3-Hydroxy-2-methyl-propionic acid could potentially be used as a natural preservative or flavor enhancer in the food industry, leveraging its inherent properties to improve food quality or extend shelf life.

InChI:InChI=1/C4H8O3/c1-3(2-5)4(6)7/h3,5H,2H2,1H3,(H,6,7)/t3-/m0/s1

Upstream product

• 535-11-5 Ethyl 2-bromopropionate 
• 909803-25-4 kaempferol 3-O-β-D-(6-O-3-hydroxyisobutyryl)glucopyranosyl-(1->4)-α-L-rhamnopyaranosyl-7-O-β-D-glucopyranoside 
• 89534-52-1 3-hydroxy-2-methyl-propionic acid ethyl ester 
• 67-56-1 methanol 
• 2163-42-0 2-methyl-1.3-propanediol 
• 56850-57-8 3-benzyloxy-2-methylpropionic acid 

Downstream Products

• 53009-01-1 β-phenylcarbamoyloxy-isobutyric acid 
• 80657-57-4 3-hydroxy-(2S)-methylpropionate 
• 72657-23-9 methyl (R)-3-hydroxy-2-methylpropionate 
• 7623-10-1 2-methyl-3-chloropropionyl chloride 
• 16837-14-2 2,2,5-trimethyl-1,3-dioxane-5-carboxylic acid 
• 91796-44-0 Benzyl 3-(phenylmethoxy)-2-methylpropanoate 
• 63930-49-4 (R)-3-(benzyloxy)-2-methylpropan-1-ol 
• 59965-08-1 (S)-(+)-3-N-Phenylcarbamoyloxy-2-methyl-propansaeure 
• 79-41-4 poly(methacrylic acid) 
• 1360106-01-9 methyl (S)-3-(3-(4-chlorobenzyl)-4-(ethylthio)-2,6-dioxo-3,6-dihydro-1,3,5-triazin-1(2H)-yl)-2-methylpropanoate 

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