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P-cyclohexylbenzaldehyde is a chemical compound characterized by a benzene ring with a cyclohexyl group and an aldehyde functional group. It is known for its strong, sweet, and floral odor, which makes it a popular ingredient in the production of fragrances and flavors. Additionally, it serves as a precursor in the synthesis of other organic compounds and has been studied for its potential anti-inflammatory and antioxidant properties, highlighting its significance in various industries.

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  • 27634-89-5 Structure
  • Basic information

    1. Product Name: p-cyclohexylbenzaldehyde
    2. Synonyms: p-cyclohexylbenzaldehyde;4-Cyclohexylbenzaldehyde;Benzaldehyde, 4-cyclohexyl-
    3. CAS NO:27634-89-5
    4. Molecular Formula: C13H16O
    5. Molecular Weight: 188.26554
    6. EINECS: 248-582-7
    7. Product Categories: N/A
    8. Mol File: 27634-89-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 309.1°Cat760mmHg
    3. Flash Point: 122.2°C
    4. Appearance: /
    5. Density: 1.032g/cm3
    6. Vapor Pressure: 0.000651mmHg at 25°C
    7. Refractive Index: 1.559
    8. Storage Temp.: 2-8°C
    9. Solubility: N/A
    10. CAS DataBase Reference: p-cyclohexylbenzaldehyde(CAS DataBase Reference)
    11. NIST Chemistry Reference: p-cyclohexylbenzaldehyde(27634-89-5)
    12. EPA Substance Registry System: p-cyclohexylbenzaldehyde(27634-89-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 27634-89-5(Hazardous Substances Data)

27634-89-5 Usage

Uses

Used in Fragrance and Flavor Industry:
P-cyclohexylbenzaldehyde is used as a key ingredient in the creation of perfumes and scented products due to its strong, sweet, and floral aroma. Its unique scent profile contributes to the development of various fragrances and flavorings in consumer products.
Used in Pharmaceutical Industry:
P-cyclohexylbenzaldehyde is used as a precursor in the synthesis of pharmaceutical compounds. Its potential anti-inflammatory and antioxidant properties make it a subject of interest in pharmaceutical research, with the aim of developing new drugs that can benefit from these characteristics.
Used in Agrochemical Industry:
In the agrochemical sector, p-cyclohexylbenzaldehyde is utilized in the production of various agrochemicals. Its chemical properties allow it to be a valuable component in the development of products used in agriculture to protect crops and enhance yields.
Used in Organic Synthesis:
P-cyclohexylbenzaldehyde is employed as a versatile building block in organic synthesis. Its reactivity and structural features make it suitable for the preparation of a wide range of organic compounds, contributing to the advancement of chemical research and the development of new materials.

Check Digit Verification of cas no

The CAS Registry Mumber 27634-89-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,6,3 and 4 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 27634-89:
(7*2)+(6*7)+(5*6)+(4*3)+(3*4)+(2*8)+(1*9)=135
135 % 10 = 5
So 27634-89-5 is a valid CAS Registry Number.
InChI:InChI=1/C13H16O/c14-10-11-6-8-13(9-7-11)12-4-2-1-3-5-12/h6-10,12H,1-5H2

27634-89-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-cyclohexylbenzaldehyde

1.2 Other means of identification

Product number -
Other names Benzaldehyde,4-cyclohexyl

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:27634-89-5 SDS

27634-89-5Relevant articles and documents

Alkyl-GeMe3: Neutral Metalloid Radical Precursors upon Visible-Light Photocatalysis

Wei, Li-Pu,Xiao, Bin,Xu, Qing-Hao

supporting information, (2022/02/17)

Single-electron transfer (SET) oxidation of ionic hypervalent complexes, in particular alkyltrifluoroborates (Alkyl-BF3?) and alkylbis(catecholato)silicates (Alkyl-Si(cat)2?), have contributed substantially to alkyl radical generation compared to alkali or alkaline earth organometallics because of their excellent activity–stability balance. Herein, another proposal is reported by using neutral metalloid compounds, Alkyl-GeMe3, as radical precursors. Alkyl-GeMe3 shows comparable activity to that of Alkyl-BF3? and Alkyl-Si(cat)2? in radical addition reactions. Moreover, Alkyl-GeMe3 is the first successful group 14 tetraalkyl nucleophile in nickel-catalyzed cross-coupling. Meanwhile, the neutral nature of these organogermanes offset the limitation of ionic precursors in purification and derivatization. A preliminary mechanism study suggests that an alkyl radical is generated from a tetraalkylgermane radical cation with the assistance of a nucleophile, which may also result in the development of more non-ionic alkyl radical precursors with a metalloid center.

Dealkenylative Ni-Catalyzed Cross-Coupling Enabled by Tetrazine and Photoexcitation

Cao, Yuhui,Che, Jinteng,Chen, Han,Chen, Si-Cong,Fang, Xianhe,Guo, Yinliang,Guo, Zhixian,Kong, Lingran,Li, Chen,Lu, Jia-Tian,Luo, Tuoping,Zhang, Nan,Zhu, Qi

, p. 14046 - 14052 (2021/09/13)

A new and general method to functionalize the C(sp3)-C(sp2) bond of alkyl and alkene linkages has been developed, leading to the dealkenylative generation of carbon-centered radicals that can be intercepted to undergo Ni-catalyzed C(sp3)-C(sp2) cross-coupling. This one-pot protocol leverages the easily procured alkene feedstocks for organic synthesis with excellent functional group compatibility without the need for a photoredox catalyst.

Micelle enabled C(sp2)-C(sp3) cross-electrophile coupling in waterviasynergistic nickel and copper catalysis

Ye, Ning,Wu, Bin,Zhao, Kangming,Ge, Xiaobin,Zheng, Yu,Shen, Xiaodong,Shi, Lei,Cortes-Clerget, Margery,Regnier, Morgan Louis,Parmentier, Michael,Gallou, Fabrice

supporting information, p. 7629 - 7632 (2021/08/09)

A robust and sustainable C(sp2)-C(sp3) cross-electrophile coupling was developedvianickel/copper synergistic catalysis under micellar conditions. This protocol provided a general method to access alkylated arenes with good to excellent yields on a very large scale.

COMPOSITION FOR FORMING RESIST UNDERLAYER FILM AND METHOD FOR FORMING PATTERN

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Paragraph 0131-0133, (2020/04/29)

The invention provides a composition for forming a resist underlayer film, comprising a compound represented by the formula (I): [LxTe(OR 1 )y] (1) (in formula (1), L is a ligand other than OR 1 R 1 is any of hydrogen atom, substituted or unsubstituted linear alkyl having 1 to 20 carbon atom or substituted or unsubstituted branched or cyclic alkyl having 3 to 20 carbon atoms, substituted or unsubstituted aryl having 6 to 20 carbon atoms, and substituted or unsubstituted alkenyl having 2 to 20 carbon atoms x is an integer of 0 to 6 y is an integer of 0 to 6 the sum of x and y is 1 to 6 a plurality of L may be the same or different when x is 2 or more and a plurality of R 1 may be the same or different when y is 2 or more).

COMPOSITION FOR RESIST UNDERLAYER FILM FORMATION, UNDERLAYER FILM FOR LITHOGRAPHY, AND PATTERN FORMATION METHOD

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Paragraph 0561; 0563-0565, (2020/08/22)

The present invention provides a composition for resist underlayer film formation comprising a tellurium-containing compound or a tellurium-containing resin.

COMPOUNDS AND METHOD OF USE

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Paragraph 1198, (2019/09/06)

This present disclosure relates to compounds with ferroptosis inducing activity, a method of treating a subject with cancer with the compounds, and combination treatments with a second therapeutic agent.

Method for synthesizing aromatic aldehyde through iron catalyzed oxidation allyl aromatic compound

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Paragraph 0093-0095; 0150, (2019/06/27)

The invention discloses a method for synthesizing aromatic aldehyde through an iron catalyzed oxidation allyl aromatic compound. According to the specific method, under the promotion effect of hydrogen silane, with air or oxygen as the oxidant, the aromatic aldehyde compound is synthesized through the iron catalyzed oxidation allyl aromatic compound, the reaction temperature is 20-150 DEG C, and the time is 0.25-60 h. The method has the advantages that a catalyst source is wide, the price is low and the environment is protected; an oxidant source is wide, the price is low and no waste is generated; the reaction conditions are mild, selectivity is high and the yield is high; a substrate source is wide and stable; a substrate functional group is high in compatibility and a substrate is widein application range; complicated small molecules are compatible and can be well converted into aldehyde. The target product separation yield can reach up to 96% under the optimized reaction conditions.

Ni-catalyzed Reductive Deaminative Arylation at sp3 Carbon Centers

Martin-Montero, Raul,Yatham, Veera Reddy,Yin, Hongfei,Davies, Jacob,Martin, Ruben

, p. 2947 - 2951 (2019/04/30)

A Ni-catalyzed reductive deaminative arylation at unactivated sp3 carbon centers is described. This operationally simple and user-friendly protocol exhibits excellent chemoselectivity profile and broad substrate scope, thus complementing existing metal-catalyzed cross-coupling reactions to forge sp3 C-C linkages. These virtues have been assessed in the context of late-stage functionalization, hence providing a strategic advantage to reliably generate structure diversity with amine-containing drugs.

Palladium-Catalyzed para-Selective Alkylation of Electron-Deficient Arenes

Jiao, Zhiwei,Lim, Li Hui,Hirao, Hajime,Zhou, Jianrong Steve

supporting information, p. 6294 - 6298 (2018/05/30)

Intermolecular alkylations of electron-deficient arenes proceed with good para selectivity. Palladium catalysts were used to generate nucleophilic alkyl radicals from alkyl halides, which then directly add onto the arenes. The arene scope and the site of

FARNESOID X RECEPTOR AGONISTS AND USES THEREOF

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Paragraph 00401, (2017/04/11)

Described herein are compounds that are farnesoid X receptor agonists, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with farnesoid X receptor activity.

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