29817-35-4

Basic information

• Product Name: N'-methylacetohydrazide
• Synonyms: N'-methylacetohydrazide;1-Acetyl-2-methylhydrazine;Acetic acid N'-methyl hydrazide;N-Methylacetohydrazonic acid
• CAS NO: 29817-35-4
• Molecular Formula: C₃H₈N₂O
• Molecular Weight: 88.10842
• EINECS: 249-876-8
• Mol File: 29817-35-4.mol

Chemical Properties

• Boiling Point: 87.8°Cat760mmHg
• Flash Point: 29.4°C
• Appearance: /
• Density: 0.949g/cm³
• CAS DataBase Reference: N'-methylacetohydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: N'-methylacetohydrazide(29817-35-4)
• EPA Substance Registry System: N'-methylacetohydrazide(29817-35-4)

Safety Data

• Hazardous Substances Data: 29817-35-4(Hazardous Substances Data)

Upstream product

• 79-20-9 acetic acid methyl ester 
• 60-34-4 methylhydrazine 

Downstream Products

• 115231-22-6 1-acetyl-2-methyl-4-phenyl thiosemicarbazide 
• 75-89-8 2,2,2-trifluoroethanol 
• 76441-36-6 3,5-Dimethyl-Δ⁴-1,3,4-oxadiazolin-2-imin 
• 126134-51-8 2-(2-acetyl-1-methylhydrazino)-3-(benzoylmethyl)pyrido<1,2-b>-as-triazinium perchlorate 
• 108-95-2 phenol 
• 115-20-8 1,1,1-trichloroethanol 
• 1146526-00-2 Methyl 5-(2-acetyl-1-methylpyrazolidin-3-yl)-8-[(4-methoxybenzyl)oxy]-[1,6]-naphthyridine-7-carboxylate 
• 6233-04-1 N',N'-dimethylacetohydrazide 
• 57-14-7 N,N-Dimethylhydrazine 

Relevant articles and documents

Evidence of an nN(amide) → π*ArInteraction in N-Alkyl- N, N′-diacylhydrazines

1,2-Dibenzoyl-1-tert-butylhydrazine (RH-5849) and related N-alkyl-N,N′-diacylhydrazines are environmentally benign insect growth regulators. Herein, we show that an unusual nN(amide) → π*Ar interaction mediated by a hydrazide amide nitrogen atom plays a crucial role in stabilizing their biologically active trans-cis (t-c) rotameric conformations. We provide NMR and IR spectroscopic evidence for the presence of these interactions, which is also supported by X-ray crystallographic and computational studies.

A Four-Component Reaction for the Synthesis of Dioxadiazaborocines

A four-component reaction for the synthesis of heterocyclic boronates is reported. Readily available hydrazides, α-hydroxy aldehydes, and two orthogonally reactive boronic acids are combined in a single step to give structurally distinct bicyclic boronates, termed dioxadiazaborocines (DODA borocines). In this remarkable process, one boronic acid reacts as a carbon nucleophile and the other as a boron electrophile to provide enantio- and diastereomerically pure heterocyclic boronates with multiple stereocenters in high yields.