31980-12-8

Basic information

• Product Name: 2,2-DIMETHYL-2H-1,3-BENZIMIDAZOLEDIIUM-1,3-DIOLATE
• Synonyms: 2,2-DIMETHYL-2H-1,3-BENZIMIDAZOLEDIIUM-1,3-DIOLATE;2,2-dimethyl-2H-1,3-benzodiazole-1,3-diium-1,3-bis(olate)
• CAS NO: 31980-12-8
• Molecular Formula: C9H10N2O2
• Molecular Weight: 178.19
• Mol File: 31980-12-8.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,2-DIMETHYL-2H-1,3-BENZIMIDAZOLEDIIUM-1,3-DIOLATE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-DIMETHYL-2H-1,3-BENZIMIDAZOLEDIIUM-1,3-DIOLATE(31980-12-8)
• EPA Substance Registry System: 2,2-DIMETHYL-2H-1,3-BENZIMIDAZOLEDIIUM-1,3-DIOLATE(31980-12-8)

Safety Data

• Hazardous Substances Data: 31980-12-8(Hazardous Substances Data)

Usage

Type of Compound

Benzimidazole derivative

Class of Compound

Organic compounds

Potential Applications

Biomedicine

Anti-inflammatory Properties

BID has been shown to possess properties that can help reduce inflammation in the body.

Antioxidant Properties

BID can help neutralize harmful free radicals, protecting cells from oxidative stress-related damage.

Potential Drug Development

Due to its anti-inflammatory and antioxidant properties, BID is a potential candidate for the development of new drugs for the treatment of inflammatory and oxidative stress-related diseases.

Unique Chemical Structure

BID's chemical structure is unique, which contributes to its biological activity and potential therapeutic applications.

Promising Candidate for Further Study

The combination of its chemical structure and biological activity make BID a promising candidate for further research and potential therapeutic applications in biomedicine.

Upstream product

• 14208-17-4 o-benzoquinone-1,2-dioxime 
• 67-64-1 acetone 
• 71-23-8 propan-1-ol 
• 480-96-6 benzofurazan oxide 
• 67-63-0 isopropyl alcohol 
• 75-26-3 isopropyl bromide 
• 79-46-9 2-nitropropane 
• 109-89-7 diethylamine 
• 66927-19-3 2,2-dimethyl-4,5,6,7-tetrahydro-2H-benzimidazole 1,3-dioxide 
• 27992-37-6 1-hydroxy-2,2-dimethyl-4,5,6,7-tetrahydrobenzimidazoline 3-oxide 
• 492-99-9 1,2-cyclohexanedionedioxime 
• 75257-99-7 4,7-dibromo-2,2-dimethyl-4,5,6,7-tetrahydro-2H-benzimidazole 1,3-dioxide 
• 127-08-2 potassium acetate 
• 75258-00-3 4,7-dibromo-2,2-dimethylcyclohepta-2H-imidazole 1,3-dioxide 

Relevant articles and documents

Photochromism of 3H-2,1,4-benzoxadiazine 4-oxides with heterocyclic substituents on the benzene ring

2H-Benzimidazole 1,3-dioxides undergo thermal isomerization to 3H-2,1,4-benzoxadiazine 4-oxides which are converted to 2H-benzimidazole 1-oxides on further heating. Irradiation of 3H-2,1,4-benzoxadiazine 4-oxides with sunlight induces their transformation

Synthesis and some properties of 2H-benzimidazole 1,3-dioxides

Abstract The synthesis of novel 2H-benzimidazole 1,3-dioxides on the basis of benzofuroxans interaction with alcohols in acids is described. The formation of a stable secondary carbocation from alcohol is necessary for formation of 2H-benzimidazole 1,3-di

Synthesis of 2H-benzimidazole 1,3-dioxides, separase inhibitors, by reaction of o-benzoquinone dioximes with ketones

The synthesis of novel 2H-benzimidazole 1,3-dioxides on the basis of o-benzoquinone dioximes interaction with ketones in the presence of acids is described. Nitration of these compounds by nitric acid in acetic acid yields the 5-nitro derivatives of 2H-benzimidazole 1,3-dioxide.

2H-benzimidazole 1,3-dioxide derivatives: A new family of water-soluble anti-trypanosomatid agents

Three series of benzimidazole N-oxide derivatives were developed and were examined for their activity against trypanosomatid parasites (Trypanosoma cruzi and Leishmania spp.). 2H-Benzimidazole 1,3-dioxides displayed remarkable in vitro activities against

FORMATION OF 2H-BENZIMIDAZOLE-1,3-DIOXIDES BY REACTION OF BENZOFUROXANS WITH ALCOHOLS AND ALKYL HALIDES IN THE PRESENCE OF ACIDS

Reaction of benzofuroxan and 5-nitrobenzofuroxan with alcohols and alkyl halides in concentrated sulfuric or perchloric acid leads to the formation of 2H-benzimidazole-1,3-dioxides.

Quinoxaline derivatives

The synthesis of quinoxaline and benzimidazole-N-oxides and of ester and amide derivatives of 3-hydroxy-2-quinoxalinecarboxylic acid by a novel process consisting of the reaction between a benzofuroxan and an activated methylene-containing compound under basic conditions.

REACTION OF DERIVATIVES OF 4,7-DIBROMO-2H-BENZIMIDAZOLE N-OXIDES WITH AMINES

The reaction of 4,7-dibromo-2,2-dimethyl-4,5,6,7-tetrahydro-2H-benzimidazole 1,3-dioxide with amines leads to 4,7-diamino-2,2-dimethyl-4,5,6,7-tetrahydro-2H-benzimidazole 1,3-dioxides, which are converted smoothly into 4,7-diamino-2,2-dimethyl-2H-benzimidazoles by the action of silica gel or aluminum oxide.Bromination of 2,2-dimethyl-4,5,6,7-tetrahydro-2H-benzimidazole 1,3-dioxide with an excess of N-bromosuccinimide gave 4,4,7,7-tetrabromo-2,2-dimethyl-4,5,6,7-tetrahydro-2H-benzimidazole 1,3-dioxide, dehydrobromination of which gave 4,7-dibromo-2,2-dimethyl-2H-benzimidazole 1,3-dioxide and 4,7-dibromo-2,2-dimethyl-2H-benzimidazole 1-oxid e.The reaction of these compounds with morpholine led to the formation of products from addition of morpholine at position 5 of the benzimidazole, and both elimination and retention of the N-oxide groups was observed.

PREPARATION AND SOME PROPERTIES OF 2H-IMIDAZOLE 1,3-DIOXIDES, DERIVATIVES OF ALICYCLIC 1,2-DIOXIMES

The corresponding 2H-imidazole 1,3-dioxides were obtained by the reaction of cyclohexanedione and cycloheptanedione 1,2-dioximes with acetone, cyclopentanone, and methyl ethyl ketone.The reactions of these compounds with hydroxylamine hydrochloride, NaBH4, a Grignard reagent, and acetic anhydride in the presence of H2SO4 were studied in the case of 2,2-dimethyl-4,5,6,7-tetrahydro-2H-benzimidazole 1,3-dioxide.Bromination of the latter and 2,2-dimethylcyclohepta-2H-imidazole 1,3-dioxide with N-bromosuccinimide gave the corresponding dibromo derivatives, the bromineatoms in which are replaced by acetoxy and hydroxy groups. 4,7-Dihydroxy-2,2-dimethyl-4,5,6,7-tetrahydro-2H-benzimidazole 1,3-dioxide, which was obtained by oxidation with MnO2, was converted to a quinone, viz., 2,2-dimethyl-4,7-dioxo-4,7-dihydro-2H-benzimidazole 1,3-dioxide.