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2',5'-Dibromoacetophenone, a chemical compound with the molecular formula C8H6Br2O, is a yellow crystalline solid. It serves as an essential intermediate in the synthesis of pharmaceuticals and organic compounds. Known for its role as a reagent in organic synthesis, particularly in the preparation of complex molecules, it has also garnered interest for its potential as an antibacterial agent and anti-inflammatory properties. Due to its moderate toxicity, it requires careful handling in laboratory settings.

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  • 32937-55-6 Structure
  • Basic information

    1. Product Name: 2',5'-DIBROMOACETOPHENONE
    2. Synonyms: 2',5'-DIBROMOACETOPHENONE;1-(2,5-dibromophenyl)ethanone;Ethanone, 1-(2,5-dibromophenyl)-
    3. CAS NO:32937-55-6
    4. Molecular Formula: C8H6Br2O
    5. Molecular Weight: 277.94
    6. EINECS: N/A
    7. Product Categories: Aromatic Acetophenones & Derivatives (substituted);Adehydes, Acetals & Ketones;Bromine Compounds
    8. Mol File: 32937-55-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2',5'-DIBROMOACETOPHENONE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2',5'-DIBROMOACETOPHENONE(32937-55-6)
    11. EPA Substance Registry System: 2',5'-DIBROMOACETOPHENONE(32937-55-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 32937-55-6(Hazardous Substances Data)

32937-55-6 Usage

Uses

Used in Pharmaceutical Industry:
2',5'-Dibromoacetophenone is used as a key intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents. Its unique chemical structure allows for the creation of a wide range of organic compounds with potential medicinal applications.
Used in Organic Synthesis:
In the field of organic synthesis, 2',5'-Dibromoacetophenone is employed as a valuable reagent, facilitating the preparation of complex molecules. Its versatility in chemical reactions makes it an indispensable tool for chemists working on the synthesis of novel organic compounds.
Used in Antibacterial Applications:
2',5'-Dibromoacetophenone has been studied for its potential as an antibacterial agent, demonstrating effectiveness against certain types of bacteria. Its ability to inhibit bacterial growth makes it a promising candidate for the development of new antimicrobial agents to combat drug-resistant infections.
Used in Anti-inflammatory Applications:
The anti-inflammatory properties of 2',5'-Dibromoacetophenone have been investigated, with potential applications in the treatment of inflammation-related conditions. Its capacity to reduce inflammation could lead to the development of new therapeutic agents for various inflammatory diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 32937-55-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,9,3 and 7 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 32937-55:
(7*3)+(6*2)+(5*9)+(4*3)+(3*7)+(2*5)+(1*5)=126
126 % 10 = 6
So 32937-55-6 is a valid CAS Registry Number.

32937-55-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2,5-dibromophenyl)ethanone

1.2 Other means of identification

Product number -
Other names 2,5-Dibrom-acetophenon

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:32937-55-6 SDS

32937-55-6Relevant articles and documents

An Improved Process for the Enantioselective Synthesis of HCV NS5A Inhibitor Elbasvir (MK-8742) Chiral Amine Intermediate

Chapala, Vijaya Lakshmi,Katari, Naresh Kumar,Kerru, Nagaraju,Malavattu, Giri Prasad,Marisetti, Vishnu Murthy,Reddy, Pedavenkatagari Narayana

, p. 932 - 938 (2021/06/26)

Abstract: Large-scale enantioselective synthesis of the chiral amine unit of HCV NS5A inhibitor Elbasvir has been accomplished in six steps, with 55% overall yield. The process includes a highly enantioselective reduction of the NH imine using R-(+)-diphe

Organic boron luminescent material, preparation method thereof and application

-

Paragraph 0037-0041, (2019/05/22)

The invention discloses an organic boron luminescent material, and belongs to the technical field of organic optoelectronic materials. The organic boron luminescent material is structurally characterized in that two organic boron units are introduced onto phenyl quinoline, B on one organic boron unit and N on adjacent quinoline can form intramolecular coordination, so that the organic boron unit has four-coordination boron properties, and the other organic boron unit has three-coordination boron properties at the adjacent position and meta-position or para-position of the quinoline, so that aPi conjugate organic boron luminescent compound is formed. The organic boron luminescent material can emit strong yellow light in a solid state. A preparation method of the organic boron luminescent material is simple in synthetic step, the prepared organic boron luminescent material can be used for luminescent materials and electron transport materials, a triaryl boron unit in the material and fluorine ions can act, and p-pi conjugation between the B and an adjacent conjugate unit is interrupted, so that the luminescent material can be used for detection of the fluorine ions.

Facile synthesis of 1-naphthols through a copper-catalyzed arylation of methyl ketones with o-bromoacetophenones

Lou, Zhen-Bang,Pang, Xin-Long,Chen, Chao,Wen, Li-Rong,Li, Ming

supporting information, p. 1231 - 1235 (2015/12/30)

The coupling reactions of simple methyl ketones with o-bromoacetophenones and subsquential cyclization reactions were realized to produce a range of 1-naphthols. These cascade reactions were initiated by a rare Cu-catalyzed arylation reaction of methyl ketones with aromatic bromides.

Base-catalyzed synthesis of substituted indazoles under mild, transition-metal-free conditions

Thome, Isabelle,Besson, Claire,Kleine, Tillmann,Bolm, Carsten

, p. 7509 - 7513 (2013/07/26)

Back to basics: A transition-metal-free method developed for the synthesis of indazoles involves an inexpensive catalytic system composed of a diamine and K2CO3. Various (Z)-2-bromoacetophenone tosylhydrazones were converted into indazoles at room temperature in excellent yields (see example; Ts=p-toluenesulfonyl). The yield was improved by photoisomerization with UV light when E/Z isomeric mixtures of the starting material were used. Copyright

Synthesis and characterization of chiral benzylic ether-bridged periodic mesoporous organosilicas

Morell, Juergen,Chatterjee, Sangam,Klar, Peter J.,Mauder, Daniel,Shenderovich, Ilja,Hoffmann, Frank,Froeba, Michael

scheme or table, p. 5935 - 5940 (2009/05/31)

The first synthesis of a chiral periodic mesoporous organosilica (PMO) carrying benzylic ether bridging groups is reported. By hydrolysis and condensation of the new designed chiral organosilica precursor 1,4-bis(triethoxysilyl)-2-(1 -methoxyethyl)benzene

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