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2-Aminopyridin-4-ol is an organic compound with the molecular formula C5H6N2O. It is a white crystalline solid and is used as an important intermediate in various fields due to its unique chemical properties.

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  • 33631-05-9 Structure
  • Basic information

    1. Product Name: 2-Aminopyridin-4-ol
    2. Synonyms: 2-Aminopyridin-4-ol, 4-Hydroxypyridin-2-amine;2-Amino-4-hydroxypyridine,98%;2-Amino-4-hydroxypyridine 2-Aminopyridin-4-ol;2-Aminopyridin-4-ol AldrichCPR;2-AMINO-PYRIDIN-4-OL;2-AMINO-4-HYDROXYPYRIDINE;2-Amino-4-hydroxypyridine97%;4-HYDROXY-2-AMINOPYRIDINE
    3. CAS NO:33631-05-9
    4. Molecular Formula: C5H6N2O
    5. Molecular Weight: 110.11
    6. EINECS: -0
    7. Product Categories: C5;Chemical Synthesis;Heterocyclic Building Blocks;New Products for Chemical Synthesis;Heterocyclic Series;pharmacetical;Pyridine;Pyridines;Amines;Building Blocks
    8. Mol File: 33631-05-9.mol
  • Chemical Properties

    1. Melting Point: 85 °C
    2. Boiling Point: 253.9 °C at 760 mmHg
    3. Flash Point: 107.4 °C
    4. Appearance: Pale yellow/Solid
    5. Density: 1.208 g/cm3
    6. Vapor Pressure: 0.0178mmHg at 25°C
    7. Refractive Index: 1.555
    8. Storage Temp.: Room temperature.
    9. Solubility: N/A
    10. PKA: 5.30±0.18(Predicted)
    11. Water Solubility: Slightly soluble in water.
    12. CAS DataBase Reference: 2-Aminopyridin-4-ol(CAS DataBase Reference)
    13. NIST Chemistry Reference: 2-Aminopyridin-4-ol(33631-05-9)
    14. EPA Substance Registry System: 2-Aminopyridin-4-ol(33631-05-9)
  • Safety Data

    1. Hazard Codes: Xn
    2. Statements: 36/37/38-41-22
    3. Safety Statements: 26-36/37/39
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 33631-05-9(Hazardous Substances Data)

33631-05-9 Usage

Uses

Used in Organic Synthesis:
2-Aminopyridin-4-ol is used as a key intermediate for the synthesis of various organic compounds. Its presence in the molecule allows for further functionalization and the creation of a wide range of products.
Used in Agrochemical Industry:
In the agrochemical industry, 2-Aminopyridin-4-ol is used as a vital intermediate for the development of new pesticides and other agricultural chemicals. Its unique structure contributes to the effectiveness of these products in controlling pests and diseases.
Used in Pharmaceutical Industry:
2-Aminopyridin-4-ol is employed as a crucial intermediate in the pharmaceutical industry for the synthesis of various drugs. Its versatile chemical properties enable the development of new therapeutic agents with potential applications in treating different medical conditions.
Used in Dyestuff Field:
2-Aminopyridin-4-ol is used as an essential intermediate for the production of dyes and pigments in the dyestuff industry. Its incorporation into dye molecules enhances their color properties and stability, leading to improved performance in various applications.

Check Digit Verification of cas no

The CAS Registry Mumber 33631-05-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,3,6,3 and 1 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 33631-05:
(7*3)+(6*3)+(5*6)+(4*3)+(3*1)+(2*0)+(1*5)=89
89 % 10 = 9
So 33631-05-9 is a valid CAS Registry Number.
InChI:InChI=1/C5H6N2O/c6-5-3-4(8)1-2-7-5/h1-3H,(H3,6,7,8)

33631-05-9 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
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  • Detail
  • Alfa Aesar

  • (H64836)  2-Amino-4-hydroxypyridine, 98%   

  • 33631-05-9

  • 1g

  • 309.0CNY

  • Detail
  • Alfa Aesar

  • (H64836)  2-Amino-4-hydroxypyridine, 98%   

  • 33631-05-9

  • 5g

  • 1235.0CNY

  • Detail
  • Aldrich

  • (L510793)  2-Aminopyridin-4-ol  AldrichCPR

  • 33631-05-9

  • L510793-1G

  • 644.67CNY

  • Detail

33631-05-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Aminopyridin-4-ol

1.2 Other means of identification

Product number -
Other names 2-amino-1H-pyridin-4-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:33631-05-9 SDS

33631-05-9Relevant articles and documents

Chemoselective Demethylation of Methoxypyridine

Makino, Kosho,Hasegawa, Yumi,Inoue, Takahide,Araki, Koji,Tabata, Hidetsugu,Oshitari, Tetsuta,Ito, Kiyomi,Natsugari, Hideaki,Takahashi, Hideyo

, p. 951 - 954 (2019/05/10)

A chemoselective demethylation method for various methoxypyridine derivatives has been developed. Treatment of 4-methoxypyridine with L-selectride in THF for 2 h at reflux temperature afforded 4-hydroxypyridine in good yield; no reaction to anisole occurred. The utility of our method was demonstrated by the efficient synthesis of the metabolic substances of the antiulcer agent omeprazole. Chemoselective demethylation at the site of 3,5-dimethyl-4-methoxypyridine in the presence of 4-methoxybenzimidazole was achieved.

Discovery of novel antileishmanial agents in an attempt to synthesize pentamidine - Aplysinopsin hybrid molecule

Porwal, Sharad,Chauhan, Shikha S.,Chauhan, Prem M. S.,Shakya, Nishi,Verma, Aditya,Gupta, Suman

supporting information; experimental part, p. 5793 - 5802 (2010/03/24)

In an attempt to synthesize pentamidine-aplysinopsin hybrid molecule 25, a lead molecule 8 (containing Z-configured aplysinopsin moiety) was identified for antileishmanial activity. Optimization of lead 8 provided 24 (containing E-configured aplysinopsin)

CNS active compounds

-

, (2008/06/13)

Compounds of the formula STR1 wherein R may be hydrogen or a straight or branched chain alkyl radical of from 1 to 10 carbon atoms, aryl of from 6 to 10 carbon atoms, or aralkyl of from 7 to 10 carbon atoms; Y may be hydrogen, alkyl of from 1 to 4 carbons, CF3, F, Cl, or Br; and Z may be hydrogen or as defined hereinafter. These compounds are useful as central nervous system stimulants or more specifically in enhancing performance or as mood elevators.

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