340774-74-5Relevant articles and documents
1-(PIPERIDIN-4-YL)-1H-INDOLE DERIVATIVE
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Page/Page column 34-35, (2010/11/28)
The present invention provides a compound represented by the formula (1) or a pharmacologically acceptable salt thereof, or a hydrate thereof (provided that a compound in which all of R4a, R4b, and R4c are hydrogen atoms is excluded.): [wherein R1 represents a hydrogen atom, R2 represents a hydrogen atom, R3 represents the formula: wherein R4a, R4b, and R4c are the same as or different from each other and each represents a hydrogen atom, a C1-6 alkyl group or a C1-6 alkoxy group, etc.]
Synthesis of 7-methoxybenzolactam-V8 using a diastereoselective Strecker synthesis
Sakamuri,Kozikowski
, p. 475 - 476 (2007/10/03)
7-Methoxybenzolactam-V8 (4) was synthesized using a diastereoselective Strecker reaction as the key step employing an ortho-substituted phenylacetaldehyde and (R)-phenylglycinol as the chiral auxiliary.