34810-62-3

Basic information

• Product Name: 4H-1-Benzopyran-4-one, 2-(4-hydroxy-3-methoxyphenyl)-5,6,7,8-tetramethoxy-
• CAS NO: 34810-62-3
• Molecular Formula: C20H20O8
• Molecular Weight: 388.374
• Mol File: 34810-62-3.mol

Chemical Properties

• CAS DataBase Reference: 4H-1-Benzopyran-4-one, 2-(4-hydroxy-3-methoxyphenyl)-5,6,7,8-tetramethoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1-Benzopyran-4-one, 2-(4-hydroxy-3-methoxyphenyl)-5,6,7,8-tetramethoxy-(34810-62-3)
• EPA Substance Registry System: 4H-1-Benzopyran-4-one, 2-(4-hydroxy-3-methoxyphenyl)-5,6,7,8-tetramethoxy-(34810-62-3)

Safety Data

• Hazardous Substances Data: 34810-62-3(Hazardous Substances Data)

Upstream product

• 1228255-36-4 (1H-benzo[d][1,2,3]triazol-1-yl)(4-(benzyloxy)-3-methoxyphenyl)methanone 
• 121-34-6 3-methoxy-4-hydroxybenzoic acid 
• 1486-53-9 4-(benzyloxy)-3-methoxybenzoic acid 
• 3162-28-5 2-hydroxy-3,4,5,6-tetramethoxyacetophenone 
• 34810-60-1 2-(3-Methoxy-4-benzyloxy-benzoyloxy)-3,4,5,6-tetramethoxyacetophenon 
• 7169-08-6 2,3,4,5,6-Pentamethoxy-benzoylchlorid 
• 92157-76-1 methyl 2,3,4,5,6-pentamethoxybenzoate 
• 91556-09-1 2,3,4,5,6-pentamethoxybenzoic acid 
• 14786-40-4 1-(2,3,4,5,6-pentamethoxyphenyl)ethan-1-one 
• 29201-96-5 C₂₇H₂₈O₉ 
• 2426-87-1 3-methoxy-4-(phenylmethoxy)benzaldehyde 
• 938041-78-2 4'-benzyloxy-3',5,6,7,8-pentamethoxyflavanone 
• 29201-97-6 4'-benzyloxy-3',5,6,7,8-pentamethoxyflavone 

Downstream Products

• 478-01-3 nobiletin 
• 16520-78-8 8-methoxycirsilineol 
• 121-34-6 3-methoxy-4-hydroxybenzoic acid 
• 2174-59-6 5-hydroxy-6,7,8,3',4'-pentamethoxyflavone 

Relevant articles and documents

Concise synthesis of polymethoxyflavone sudachitin and its derivatives, and biological evaluations

We accomplished a divergent synthesis of sudachitin (2), a polymethoxyflavone isolated from citrus fruits, and six derivatives from acetophenone 9, which was an intermediate in our previous synthesis of nobiletin (1). Compound 2 enhanced glucose-induced i

Synthetic studies of fisetin, myricetin and nobiletin analogs and related probe molecules

We synthesized a series of analogs of fisetin, myricetin and nobiletin, as well as related fluorescein- and biotin-based flavone-probe molecules, on a suitable scale for biological and structure-activity relationship studies.

Nobiletin metabolites: Synthesis and inhibitory activity against matrix metalloproteinase-9 production

A divergent synthesis of nobiletin metabolites was developed through highly oxygenated acetophenone derivative. We used commercially available methyl 3,4,5-trimethoxybenzoate as a starting material for concise preparation of the key intermediate, 2′-hydro

Isolation and syntheses of polymethoxyflavones and hydroxylated polymethoxyflavones as inhibitors of HL-60 cell lines

Fifteen polymethoxyflavones (PMFs) and hydroxylated PMFs were isolated from sweet orange (Citrus sinensis) peel extract and synthesized to investigate their biological activity. All obtained compounds were tested in HL-60 cancer cell proliferation and apoptosis induction assays. While some PMFs and hydroxylated PMFs had moderate anti-carcinogenic activities, 5-hydroxy-6,7,8,3′,4′-pentamethoxyflavone and 5-hydroxy-3,6,7,8,3′,4′-hexamethoxyflavone showed strong inhibitory activities against the proliferation and induced apoptosis of HL-60 cell lines.

The Structure and Synthesis of Sudachiin A, a New Flavone Glucoside from Citrus Sudachi

Sudachiin A was isolated from the green peels of Citrus sudachi Hort. ex Shirai.This structure was deduced to be sudachitin 4'-β-D-glucoside by means of its spectra and degradation; this was confirmed by the synthesis of the one from sudachitin 7-benzyl ether and α-acetobromoglucose via several steps. 4',5,7-Trihydroxy-3',6,8-trimethoxyflavone 7-glucoside (sudachitin 7-β-D-glucoside), which was isolated from Sideritis leucantha Cavanilles, was also synthesized from sudachitin and α-acetobromoglucose in a similar manner.