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2-tert-butyl 5-methyl isoindoline-2,5-dicarboxylate is a chemical compound with the molecular formula C15H21NO4. It is a tertiary butyl ester of isoindoline-2,5-dicarboxylic acid, known for its potential as a bioactive molecule and its applications in the synthesis of pharmaceuticals and agrochemicals. 2-tert-butyl 5-methyl isoindoline-2,5-dicarboxylate exhibits anti-inflammatory and antioxidant properties, making it a promising candidate for the development of new drugs. Furthermore, it serves as a building block in the synthesis of various organic compounds and is utilized in organic reactions for the preparation of new chemical entities.

368441-44-5

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  • 2H-Isoindole-2,5-dicarboxylic acid, 1,3-dihydro-, 2-(1,1-dimethylethyl) 5-methyl ester

    Cas No: 368441-44-5

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368441-44-5 Usage

Uses

Used in Pharmaceutical Industry:
2-tert-butyl 5-methyl isoindoline-2,5-dicarboxylate is used as an intermediate in the synthesis of pharmaceuticals for its potential as a bioactive molecule. Its anti-inflammatory and antioxidant properties contribute to the development of new drugs with therapeutic benefits.
Used in Agrochemical Industry:
In the agrochemical industry, 2-tert-butyl 5-methyl isoindoline-2,5-dicarboxylate is used as an intermediate in the synthesis of agrochemicals, leveraging its bioactive properties to create compounds with potential applications in agriculture.
Used in Organic Synthesis:
2-tert-butyl 5-methyl isoindoline-2,5-dicarboxylate is used as a building block in the synthesis of various organic compounds. Its versatility in organic reactions allows for the preparation of new chemical entities with potential applications in various fields.
Used in Research and Development:
2-tert-butyl 5-methyl isoindoline-2,5-dicarboxylate is utilized in research and development for the exploration of its anti-inflammatory and antioxidant properties, as well as its potential applications in drug development and other industries.

Check Digit Verification of cas no

The CAS Registry Mumber 368441-44-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,6,8,4,4 and 1 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 368441-44:
(8*3)+(7*6)+(6*8)+(5*4)+(4*4)+(3*1)+(2*4)+(1*4)=165
165 % 10 = 5
So 368441-44-5 is a valid CAS Registry Number.

368441-44-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-O-tert-butyl 5-O-methyl 1,3-dihydroisoindole-2,5-dicarboxylate

1.2 Other means of identification

Product number -
Other names 2-tert-butyl 5-methyl isoindoline-2,5-dicarboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:368441-44-5 SDS

368441-44-5Relevant articles and documents

ISOINDOLINE DERIVATIVES WHICH BIND TO AN ATP BINDING SITE

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Paragraph 00150-00151, (2021/07/31)

The present invention relates to novel probe compounds of formulae I and II defined herein. The present invention also relates to methods of synthesising these novel probe compounds and to their use in assays and screens for determining the binding of a test molecule to the ATP-binding site of a target protein, such as, for example, the Mismatch Repair (MMR) component proteins PMS2 and MLH1, or for determining the location and/or quantity of such target proteins in a biological sample.

2-Amino-2,3-dihydro-1 H-indene-5-carboxamide-Based Discoidin Domain Receptor 1 (DDR1) Inhibitors: Design, Synthesis, and in Vivo Antipancreatic Cancer Efficacy

Zhu, Dongsheng,Huang, Huocong,Pinkas, Daniel M.,Luo, Jinfeng,Ganguly, Debolina,Fox, Alice E.,Arner, Emily,Xiang, Qiuping,Tu, Zheng-Chao,Bullock, Alex N.,Brekken, Rolf A.,Ding, Ke,Lu, Xiaoyun

, p. 7431 - 7444 (2019/08/20)

A series of 2-amino-2,3-dihydro-1H-indene-5-carboxamides were designed and synthesized as new selective discoidin domain receptor 1 (DDR1) inhibitors. One of the representative compounds, 7f, bound with DDR1 with a Kd value of 5.9 nM and suppre

HETEROCYCLIC COMPOUND

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, (2017/08/01)

The problem of the present invention is to provide a compound having a superior RORγt inhibitory action, and useful as a prophylactic or therapeutic agent for psoriasis, inflammatory bowel disease, ulcerative colitis, Crohn's disease, rheumatoid arthritis, multiple sclerosis, uveitis, asthma, ankylopoietic spondylarthritis, systemic lupus erythematosus, chronic obstructive pulmonary disease or the like. The present invention relates to a compound represented by the formula (I): [wherein each symbol is as described in the DESCRIPTION] or a salt thereof, which has an RORγt inhibitory action, and useful as a prophylactic or therapeutic agent for psoriasis, inflammatory bowel disease, ulcerative colitis, Crohn's disease, rheumatoid arthritis, multiple sclerosis, uveitis, asthma, ankylopoietic spondylarthritis, systemic lupus erythematosus, chronic obstructive pulmonary disease or the like.

Benzenesulfonyl-Asymmetric Ureas and Medical Uses Thereof

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, (2017/10/10)

Benzenesulfonyl-asymmetric ureas are provided for the treatment of conditions modulated by the ghrelin receptor.

HETERO-HALO INHIBITORS OF HISTONE DEACETYLASE

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Paragraph 618, (2017/01/26)

This invention provides compounds that are inhibitors of HDAC2. The compounds (e.g., compounds according to Formula I, II or any of Compounds 100-128 or any of those in Tables 2 or 3) accordingly are useful for treating, alleviating, or preventing a condition in a subject such as a neurological disorder, memory or cognitive function disorder or impairment, extinction learning disorder, fungal disease or infection, inflammatory disease, hematological disease, or neoplastic disease, or for improving memory or treating, alleviating, or preventing memory loss or impairment.

MACROCYCLIC CARBOXYLIC ACIDS AND ACYLSULFONAMIDES AS INHIBITORS OF HCV REPLICATION

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Page/Page column 202, (2008/06/13)

The present invention provides compounds of the general formulas I-IX, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The present invention further provides treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.

Macrocyclic compounds as inhibitors of viral replication

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, (2008/06/13)

The embodiments provide compounds of the general formulas I-XIX, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating flaviviral infection, including hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.

BICYCLIC BENZAMIDE COMPOUNDS AS HISTAMINE H3 RECEPTOR LIGAND USEFUL IN THE TREATMENT OF NEUROLOGICAL DISEASES

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Page 15, (2008/06/13)

The present invention relates to novel bicyclic benzamide derivatives having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of neurological and psychiatric disorders.

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